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The map label for this gene is yagE [H]

Identifier: 121610471

GI number: 121610471

Start: 3916745

End: 3917656

Strand: Direct

Name: yagE [H]

Synonym: Veis_3541

Alternate gene names: 121610471

Gene position: 3916745-3917656 (Clockwise)

Preceding gene: 121610470

Following gene: 121610472

Centisome position: 70.36

GC content: 68.09

Gene sequence:

>912_bases
ATGCAGAAATACCGGCCCGAAGACCTGCACGGCATCCACGCCATCGTCTACGCCTTGTTCGACGCCGACGAGCGACTGGA
CCGCGCAGCCATGCGGCGCCAGGTGCAGGCTTGTTTGTCCTGCGGGGTCCACGGCATGGCAGCGCTCGGACTGGCCACCG
AGGTGTCCAAGCTCACCGAAGCCGAGCGCCGCACGGTCATGGACTGGGTGGCCGAAGACACTGCGGGCAAGGTGCCGCTG
GCGTTCACCATCTTCGGCGCCTCGGTCGCCGAGCAGACGGCCCAACTGCGGCATGCCCAGCAGGCCGGCGCAGATTGGGT
GATCCTGCAACCACCGACGGTTGGCACGTTCAGCGCCGCAGAGTACATCCGCTTCTTTGGTCGCGTCGCCCAGGCCACCA
CCCTTCCCGTGGCGATACAGAACGCGCCCGCCTTCCTCGGTCGCGGTCTGTCGGCGGACGAAATCCGCGAACTCGTCGAG
CAACAGCCGAACATCCGATTGATCAAGGGCGAAGGGCCGGTGGTGGAAATTGCCGGGCTGCTGGAACGCACCGCAGGCCG
CGTGTCCGTCTTCAACGGCCGTGGCGGGCTGGAACTGGTGGACAACCTGCGCGCCGGTTGCCGCGGGATGATTCTGGCGC
CCGACTGCATCGACTACGCAGTCAGCGCCTACGAGGCTTGGCGCAGCGGCGACGAAGCGCGCGCCGAATGCCAGTACCGC
GAGATGCTGCCGGCCGTCGTCTTCGTGATGCAAGGCGTGGAAAACCTGCTGTGCTACGGCAAACGCCTGTTCGGCGCGCG
CGCGGGCATCGCCATCCACGACCGCGCCCCGGCGCAGCGCGCCACGCCGGCCGGCGCGGCCATGGTCGAGCGTTTCGCAG
CGGCACTGGGGGCCTTGGGTGATGCGCGCTGA

Upstream 100 bases:

>100_bases
ACGTCGAGCGCGTGATGCAGGCCGACAGCGGCGCCGACCTGGACTTCCTGGTCGGTTGTCGCGGCCATGCCATCCCGCGT
GAAAGCCATTGAGAGCGGCC

Downstream 100 bases:

>100_bases
CGCACCGGCGGCCTGCGGTCAGCGCCGGTGACCGCAGGTCAGGCACGAACCCCCGGCCACGCCCGGCAGATGCCGCGATG
AATGCATCCAACCCCGGCCA

Product: dihydrodipicolinate synthetase

Products: dihydrodipicolinate; H2O

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MQKYRPEDLHGIHAIVYALFDADERLDRAAMRRQVQACLSCGVHGMAALGLATEVSKLTEAERRTVMDWVAEDTAGKVPL
AFTIFGASVAEQTAQLRHAQQAGADWVILQPPTVGTFSAAEYIRFFGRVAQATTLPVAIQNAPAFLGRGLSADEIRELVE
QQPNIRLIKGEGPVVEIAGLLERTAGRVSVFNGRGGLELVDNLRAGCRGMILAPDCIDYAVSAYEAWRSGDEARAECQYR
EMLPAVVFVMQGVENLLCYGKRLFGARAGIAIHDRAPAQRATPAGAAMVERFAAALGALGDAR

Sequences:

>Translated_303_residues
MQKYRPEDLHGIHAIVYALFDADERLDRAAMRRQVQACLSCGVHGMAALGLATEVSKLTEAERRTVMDWVAEDTAGKVPL
AFTIFGASVAEQTAQLRHAQQAGADWVILQPPTVGTFSAAEYIRFFGRVAQATTLPVAIQNAPAFLGRGLSADEIRELVE
QQPNIRLIKGEGPVVEIAGLLERTAGRVSVFNGRGGLELVDNLRAGCRGMILAPDCIDYAVSAYEAWRSGDEARAECQYR
EMLPAVVFVMQGVENLLCYGKRLFGARAGIAIHDRAPAQRATPAGAAMVERFAAALGALGDAR
>Mature_303_residues
MQKYRPEDLHGIHAIVYALFDADERLDRAAMRRQVQACLSCGVHGMAALGLATEVSKLTEAERRTVMDWVAEDTAGKVPL
AFTIFGASVAEQTAQLRHAQQAGADWVILQPPTVGTFSAAEYIRFFGRVAQATTLPVAIQNAPAFLGRGLSADEIRELVE
QQPNIRLIKGEGPVVEIAGLLERTAGRVSVFNGRGGLELVDNLRAGCRGMILAPDCIDYAVSAYEAWRSGDEARAECQYR
EMLPAVVFVMQGVENLLCYGKRLFGARAGIAIHDRAPAQRATPAGAAMVERFAAALGALGDAR

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1786463, Length=241, Percent_Identity=29.8755186721992, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082415, Length=267, Percent_Identity=26.5917602996255, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789620, Length=153, Percent_Identity=31.3725490196078, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: 4.2.1.52

Molecular weight: Translated: 32682; Mature: 32682

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKYRPEDLHGIHAIVYALFDADERLDRAAMRRQVQACLSCGVHGMAALGLATEVSKLTE
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
AERRTVMDWVAEDTAGKVPLAFTIFGASVAEQTAQLRHAQQAGADWVILQPPTVGTFSAA
HHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHH
EYIRFFGRVAQATTLPVAIQNAPAFLGRGLSADEIRELVEQQPNIRLIKGEGPVVEIAGL
HHHHHHHHHHHHHHCCEEECCCHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHH
LERTAGRVSVFNGRGGLELVDNLRAGCRGMILAPDCIDYAVSAYEAWRSGDEARAECQYR
HHHCCCCEEEECCCCCHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHH
EMLPAVVFVMQGVENLLCYGKRLFGARAGIAIHDRAPAQRATPAGAAMVERFAAALGALG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
DAR
CCC
>Mature Secondary Structure
MQKYRPEDLHGIHAIVYALFDADERLDRAAMRRQVQACLSCGVHGMAALGLATEVSKLTE
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
AERRTVMDWVAEDTAGKVPLAFTIFGASVAEQTAQLRHAQQAGADWVILQPPTVGTFSAA
HHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHH
EYIRFFGRVAQATTLPVAIQNAPAFLGRGLSADEIRELVEQQPNIRLIKGEGPVVEIAGL
HHHHHHHHHHHHHHCCEEECCCHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHH
LERTAGRVSVFNGRGGLELVDNLRAGCRGMILAPDCIDYAVSAYEAWRSGDEARAECQYR
HHHCCCCEEEECCCCCHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHH
EMLPAVVFVMQGVENLLCYGKRLFGARAGIAIHDRAPAQRATPAGAAMVERFAAALGALG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
DAR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate 4-semialdehyde; pyruvate

Specific reaction: L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]