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The map label for this gene is erpA [H]

Identifier: 121609596

GI number: 121609596

Start: 2985006

End: 2985371

Strand: Direct

Name: erpA [H]

Synonym: Veis_2642

Alternate gene names: 121609596

Gene position: 2985006-2985371 (Clockwise)

Preceding gene: 121609595

Following gene: 121609599

Centisome position: 53.62

GC content: 59.84

Gene sequence:

>366_bases
ATGAGCGCCGTTGCCGAAAACATCCAGACCGGAATGCCCGCACCCATCCTGTTCACCGACAGCGCAGCGGCCAAGGTGGC
GCAGCTGATTGCCGAGGAGGGCAACCCTGAGCTCAAACTGCGCGTGTTCGTGCAAGGCGGCGGCTGCTCGGGCTTTCAGT
ACGGTTTCACCTTCGATGAAATCACCAACGAAGACGACACCACGATGACCAAGAACGGTGTCTCGCTGCTGATCGATGCG
ATGAGCTACCAGTACCTGGTCGGCGCCGAGATCGACTACAAGGAAGACCTGCAGGGCGCGCAGTTCGTCATCAAGAACCC
GAACGCGACCACCACCTGCGGCTGCGGTTCGAGCTTTTCTGCATGA

Upstream 100 bases:

>100_bases
CAAAAGCCCCCACTGGAACTGGCGTCAAGCCGCCAGTGAGCGCAATTCCCGAGCAGTTTGCAGTAGTATTCCCGGCCATA
CCCTGAACCCGGAGTACCCC

Downstream 100 bases:

>100_bases
GCGCCGCACGGCCGCCCGAAGGCGCTCATACCGTAGCCGAAGGCGAAGGTACTCCAATGAGCGCCAGCGCCGGACCGGTT
CAGCGCGGGTACACCGCGCC

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSAVAENIQTGMPAPILFTDSAAAKVAQLIAEEGNPELKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDA
MSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFSA

Sequences:

>Translated_121_residues
MSAVAENIQTGMPAPILFTDSAAAKVAQLIAEEGNPELKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDA
MSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFSA
>Mature_120_residues
SAVAENIQTGMPAPILFTDSAAAKVAQLIAEEGNPELKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDAM
SYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFSA

Specific function: Required for insertion of 4Fe-4S clusters (Potential) [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=106, Percent_Identity=39.622641509434, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI52426768, Length=121, Percent_Identity=33.0578512396694, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=64.1509433962264, Blast_Score=152, Evalue=6e-39,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=34.9056603773585, Blast_Score=69, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=38.8888888888889, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=112, Percent_Identity=32.1428571428571, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=107, Percent_Identity=31.7757009345794, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=104, Percent_Identity=37.5, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649697, Length=82, Percent_Identity=48.780487804878, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642263, Length=108, Percent_Identity=32.4074074074074, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12848; Mature: 12717

Theoretical pI: Translated: 3.87; Mature: 3.87

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVAENIQTGMPAPILFTDSAAAKVAQLIAEEGNPELKLRVFVQGGGCSGFQYGFTFDE
CCCHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHH
ITNEDDTTMTKNGVSLLIDAMSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFS
HCCCCCCEEECCCCEEEEECCCCEEEECCCCCCHHCCCCCEEEEECCCCCEEECCCCCCC
A
C
>Mature Secondary Structure 
SAVAENIQTGMPAPILFTDSAAAKVAQLIAEEGNPELKLRVFVQGGGCSGFQYGFTFDE
CCHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHH
ITNEDDTTMTKNGVSLLIDAMSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFS
HCCCCCCEEECCCCEEEEECCCCEEEECCCCCCHHCCCCCEEEEECCCCCEEECCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA