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The map label for this gene is blh [H]

Identifier: 120613349

GI number: 120613349

Start: 5263823

End: 5264749

Strand: Direct

Name: blh [H]

Synonym: Aave_4719

Alternate gene names: 120613349

Gene position: 5263823-5264749 (Clockwise)

Preceding gene: 120613344

Following gene: 120613355

Centisome position: 98.34

GC content: 72.06

Gene sequence:

>927_bases
ATGACATCCCTTTCCCTGCCCTCTTCCACCGGAGCGACCTCCACGGTGCAGCCGTTCTACGATGGCGCGACCGGAACCGT
GTCCTACGTGGTCTGGGACCATGCCACCCGCCAGGCGGCGGTGATCGATCCGGTGCTGGACTACGACCCCGATGCCGGAC
GCACGCACGGCGCTTCCGCGCGGCGGCTGCTGGACTACCTGCAGGCCGAGCGCCTGGTCGTGGAATGGATCCTGGAAACA
CATGCCCATGCGGACCACCTCTCCGCCGCCCGCCACATCCAGGCGGCCAAGGGCGGCAAGGTGGCCATCGGGGCAGCCAT
CCGCACGGTGCAGCGCACCTTCGGCCCGCTGTTCGGCATGGAGCCCTCCGCACAGGACGACAGTTTCGACCACCTGTTCG
AGGACGGCGAAGTGTTCCGCATCGGCGCCACCCGGGCGGAGGCGATCGGTGTGCCGGGCCATACGCCGGCGGACATGGCC
TACCGGATCGACGGGGCGGTGTTCGTGGGCGACACGCTGTTCCTGCCCGACGTGGGCACGGCCCGGGCGGACTTCCCCGG
CGGGGATGCCGCGGCCCTCTACCGCTCCATCCAGCGGCTGCTGGCACTGCCGGGGGACACGCGCATGTTCGTGTGCCACG
ACTACCCGCCCGCGGGCCGGGCGCCGGCCTGCGAGACGACGGTGGAGGCCCAGCGGCGGAGCAACATCCACGTGGGCCGG
CAGGCTGGCGAGCGCGCCTTCGTGGCGCTGCGCCAGGCGCGCGACGCCACCCTGGCCGTGCCGCGCCTGCTGCTGCCGTC
GATCCAGGTGAACGTCCGCGGCGGCCGGCTGCCGGACCCGGGGCCGGAAGGCATCGCGTACCTGCGCATACCGCTGAACG
TGTTCGGCAGCGCGGATGCCCTTTCCGGCGCCACGCCCGCCTCCTGA

Upstream 100 bases:

>100_bases
GGTGGAGGAAAGGGACGGCATGGAGGGGATGTCAGACGGCGTTGACATCAATATATCAAAAAACATAATATTTAAAAACA
TACTGATGGACGGAGCCGCC

Downstream 100 bases:

>100_bases
GGTGGCATGGCTGCTCTCCTACCCGCGTTCAGGCAGGGTGCCCACCGCCCCGCCGCCCCGGCTGCGCGATGCTGCAGGCA
TCGGCCAGCCCTCCGCCGGC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTSLSLPSSTGATSTVQPFYDGATGTVSYVVWDHATRQAAVIDPVLDYDPDAGRTHGASARRLLDYLQAERLVVEWILET
HAHADHLSAARHIQAAKGGKVAIGAAIRTVQRTFGPLFGMEPSAQDDSFDHLFEDGEVFRIGATRAEAIGVPGHTPADMA
YRIDGAVFVGDTLFLPDVGTARADFPGGDAAALYRSIQRLLALPGDTRMFVCHDYPPAGRAPACETTVEAQRRSNIHVGR
QAGERAFVALRQARDATLAVPRLLLPSIQVNVRGGRLPDPGPEGIAYLRIPLNVFGSADALSGATPAS

Sequences:

>Translated_308_residues
MTSLSLPSSTGATSTVQPFYDGATGTVSYVVWDHATRQAAVIDPVLDYDPDAGRTHGASARRLLDYLQAERLVVEWILET
HAHADHLSAARHIQAAKGGKVAIGAAIRTVQRTFGPLFGMEPSAQDDSFDHLFEDGEVFRIGATRAEAIGVPGHTPADMA
YRIDGAVFVGDTLFLPDVGTARADFPGGDAAALYRSIQRLLALPGDTRMFVCHDYPPAGRAPACETTVEAQRRSNIHVGR
QAGERAFVALRQARDATLAVPRLLLPSIQVNVRGGRLPDPGPEGIAYLRIPLNVFGSADALSGATPAS
>Mature_307_residues
TSLSLPSSTGATSTVQPFYDGATGTVSYVVWDHATRQAAVIDPVLDYDPDAGRTHGASARRLLDYLQAERLVVEWILETH
AHADHLSAARHIQAAKGGKVAIGAAIRTVQRTFGPLFGMEPSAQDDSFDHLFEDGEVFRIGATRAEAIGVPGHTPADMAY
RIDGAVFVGDTLFLPDVGTARADFPGGDAAALYRSIQRLLALPGDTRMFVCHDYPPAGRAPACETTVEAQRRSNIHVGRQ
AGERAFVALRQARDATLAVPRLLLPSIQVNVRGGRLPDPGPEGIAYLRIPLNVFGSADALSGATPAS

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=215, Percent_Identity=28.3720930232558, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1787158, Length=200, Percent_Identity=28.5, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=256, Percent_Identity=24.21875, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221330176, Length=260, Percent_Identity=28.0769230769231, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32773; Mature: 32642

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLSLPSSTGATSTVQPFYDGATGTVSYVVWDHATRQAAVIDPVLDYDPDAGRTHGASA
CCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCCCEEECHHHCCCCCCCCCCCHHH
RRLLDYLQAERLVVEWILETHAHADHLSAARHIQAAKGGKVAIGAAIRTVQRTFGPLFGM
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCC
EPSAQDDSFDHLFEDGEVFRIGATRAEAIGVPGHTPADMAYRIDGAVFVGDTLFLPDVGT
CCCCCCCCHHHHHCCCCEEEEECCHHHEECCCCCCCCCEEEEECCEEEECCEEECCCCCC
ARADFPGGDAAALYRSIQRLLALPGDTRMFVCHDYPPAGRAPACETTVEAQRRSNIHVGR
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCEECH
QAGERAFVALRQARDATLAVPRLLLPSIQVNVRGGRLPDPGPEGIAYLRIPLNVFGSADA
HCCHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECEECCCCCC
LSGATPAS
CCCCCCCC
>Mature Secondary Structure 
TSLSLPSSTGATSTVQPFYDGATGTVSYVVWDHATRQAAVIDPVLDYDPDAGRTHGASA
CCCCCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCCCEEECHHHCCCCCCCCCCCHHH
RRLLDYLQAERLVVEWILETHAHADHLSAARHIQAAKGGKVAIGAAIRTVQRTFGPLFGM
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCC
EPSAQDDSFDHLFEDGEVFRIGATRAEAIGVPGHTPADMAYRIDGAVFVGDTLFLPDVGT
CCCCCCCCHHHHHCCCCEEEEECCHHHEECCCCCCCCCEEEEECCEEEECCEEECCCCCC
ARADFPGGDAAALYRSIQRLLALPGDTRMFVCHDYPPAGRAPACETTVEAQRRSNIHVGR
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCEECH
QAGERAFVALRQARDATLAVPRLLLPSIQVNVRGGRLPDPGPEGIAYLRIPLNVFGSADA
HCCHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECEECCCCCC
LSGATPAS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]