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The map label for this gene is kup

Identifier: 120613174

GI number: 120613174

Start: 5056076

End: 5057944

Strand: Reverse

Name: kup

Synonym: Aave_4541

Alternate gene names: 120613174

Gene position: 5057944-5056076 (Counterclockwise)

Preceding gene: 120613175

Following gene: 120613173

Centisome position: 94.49

GC content: 64.31

Gene sequence:

>1869_bases
GTGCAACGCTCCAAATCCTCGCTTGCGGCGCTCACACTCGGCGCCATCGGCGTCGTATATGGCGACATCGGCACCAGCGT
GCTGTATGCCGTCAAGGAAGTCTTCGGCTCCGGCCACGTGGCCTTCACGCCCCAGAACGTCTACGGCGTCCTCTCCATCC
TTTTCTGGACGCTCACCACCATCGTCTCGCTGAAGTATGTCGTGCTCGTCCTGCGGGCGGACAACAACGGCGAAGGCGGG
CTCATCGCCATGCTGGCACTGGCCTCCCAGGCCGTGAAGGACAAACCGAGACTGCGCTCCGCGCTGCTGGGCATCGGCGT
CTTCGGAACCTCCCTGTTCTACGGCGACGGGGTCATCACGCCCGCCATATCCGTGCTCTCGGCGGTGGAAGGGCTCGAGG
TCGTTTCGCCGCACTTCGGCAAAGCCGTCATACCCCTGACGCTCATCGTGCTGTTCTGCCTGTTTGCCGTGCAAAAGCGC
GGCACCAGTGGCATCGGGCGCTACTTCGGCCCGGTCACGCTCGTGTGGTTCACCTCCATCGCCGCCCTGGGCGTGCCGCA
CATCGTGGGCCATCCGGAAATCCTGGGTGCCCTCAGCCCGCACCACGCCCTCGGCTTCATCTGGCGCAGCCCGGGAACGA
GCTTCATCATCCTCGGCGCCGTGGTCCTCTGCGTGACCGGTGCCGAAGCCCTCTACGCCGATCTCGGGCACTTCGGAAAG
AAGCCGATCCGCCTGGCATGGTTCAGCGTGGCCATGCCCGCCCTCACCATCAACTACTTCGGGCAGGGCGCCCTGCTGCT
CGCGGAGCCGGAAGCCGTCAAGAACCCTTTCTACATGATGGCTCCCGACTGGGCGCTCATTCCGCTCGTGATCATGGCCA
CGATGGCCACCGTCATCGCGTCCCAGGCCCTGATCACCGGAGCATTCAGCGTGACCAAGCAGGTCATCCAACTGGGCTAC
CTGCCACGGCTGAACATCCTGCACACCAGCGTGCGCGATACCGGCCAGATCTACATACCGTTCGTCAACTGGGCGCTGTT
CCTCGCCATCGTCCTGGCCGTAGTCATGTTCCGTTCCAGCAGCAATCTCGCGGCCGCCTATGGCATCGCCGTCACGCTGG
ACATGCTCATCACGACCGTGCTCACCTTCTTCGTCATCCGCTATGGCTGGCGGTATCCGCTGGCGCTGTGCATCGCGGCC
ACGGGCTTCTTCTTCCTCGTGGATCTCGCCTTCTTCGGCTCCAACCTGCTCAAGCTGCTGCAGGGCGGCTGGTTCCCGCT
GATGATCGGCTCCATCGTCTTCATGCTCATGATGACCTGGAAGCGCGGCCGCGAGCTCCTGAACGAGAAGCTGCGCGCCG
ATGCCATCGACCTGAGGGACTTCCTCACGGCGGTGTTCGTCAATCCCCCGACCCGCGTGGACGGCACGGCGGTCTTCCTG
ACGGCGGAGCCGGGAGCGGTGCCGAACGCGCTGCTCCACAACCTCAAGCACAACAAGGTCCTGCACCAGCAGAACCTTTT
CGTCACCGTACGCAACCACGAAGTCCCCTGGATCGGCCTCGACAAACGCCTGCAGGTCGAGGCGCTCGGCGGCGACTGCT
GGCAGGTCATGGTGCACTACGGCTTCAAGAACGACCCTGACCTCCCGGGCGCGCTGGCACTCATGCGCGGGCGCGGGTGC
GAACTGGAGTCGATGACCACCAGCTACTTCCTCTCCCGGGACGTGGTCACCCCGACGATCGGCAGCGGCATGGCACCCTG
GCGGGAAAAGCTCTTCGCCCAGATGCACCACAACGCGAGCGGCGCCGCAGGCTTTCTCAACCTCCCCAGCAATTCCGTGG
TGGAACTGGGCTCCAAGATCGAGATCTGA

Upstream 100 bases:

>100_bases
ACATGGAGCGGGCGGCCGGAGCGCTTTCCCTGCTCCTTGTCACAATAGCGGTCCCCCAATACCGGAACCCCGTCCGGCAC
GGTGCCGGAGGGACCCTGCA

Downstream 100 bases:

>100_bases
AAGTACAGGAAGGGGCAGCCCCGGGCAGCCCGGGGCCATCCTCATGGAGCAGGATGGACGCCCGTGCAGAGTGACAGAAT
CCTGCCCCTCATGCGCTCCT

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MQRSKSSLAALTLGAIGVVYGDIGTSVLYAVKEVFGSGHVAFTPQNVYGVLSILFWTLTTIVSLKYVVLVLRADNNGEGG
LIAMLALASQAVKDKPRLRSALLGIGVFGTSLFYGDGVITPAISVLSAVEGLEVVSPHFGKAVIPLTLIVLFCLFAVQKR
GTSGIGRYFGPVTLVWFTSIAALGVPHIVGHPEILGALSPHHALGFIWRSPGTSFIILGAVVLCVTGAEALYADLGHFGK
KPIRLAWFSVAMPALTINYFGQGALLLAEPEAVKNPFYMMAPDWALIPLVIMATMATVIASQALITGAFSVTKQVIQLGY
LPRLNILHTSVRDTGQIYIPFVNWALFLAIVLAVVMFRSSSNLAAAYGIAVTLDMLITTVLTFFVIRYGWRYPLALCIAA
TGFFFLVDLAFFGSNLLKLLQGGWFPLMIGSIVFMLMMTWKRGRELLNEKLRADAIDLRDFLTAVFVNPPTRVDGTAVFL
TAEPGAVPNALLHNLKHNKVLHQQNLFVTVRNHEVPWIGLDKRLQVEALGGDCWQVMVHYGFKNDPDLPGALALMRGRGC
ELESMTTSYFLSRDVVTPTIGSGMAPWREKLFAQMHHNASGAAGFLNLPSNSVVELGSKIEI

Sequences:

>Translated_622_residues
MQRSKSSLAALTLGAIGVVYGDIGTSVLYAVKEVFGSGHVAFTPQNVYGVLSILFWTLTTIVSLKYVVLVLRADNNGEGG
LIAMLALASQAVKDKPRLRSALLGIGVFGTSLFYGDGVITPAISVLSAVEGLEVVSPHFGKAVIPLTLIVLFCLFAVQKR
GTSGIGRYFGPVTLVWFTSIAALGVPHIVGHPEILGALSPHHALGFIWRSPGTSFIILGAVVLCVTGAEALYADLGHFGK
KPIRLAWFSVAMPALTINYFGQGALLLAEPEAVKNPFYMMAPDWALIPLVIMATMATVIASQALITGAFSVTKQVIQLGY
LPRLNILHTSVRDTGQIYIPFVNWALFLAIVLAVVMFRSSSNLAAAYGIAVTLDMLITTVLTFFVIRYGWRYPLALCIAA
TGFFFLVDLAFFGSNLLKLLQGGWFPLMIGSIVFMLMMTWKRGRELLNEKLRADAIDLRDFLTAVFVNPPTRVDGTAVFL
TAEPGAVPNALLHNLKHNKVLHQQNLFVTVRNHEVPWIGLDKRLQVEALGGDCWQVMVHYGFKNDPDLPGALALMRGRGC
ELESMTTSYFLSRDVVTPTIGSGMAPWREKLFAQMHHNASGAAGFLNLPSNSVVELGSKIEI
>Mature_622_residues
MQRSKSSLAALTLGAIGVVYGDIGTSVLYAVKEVFGSGHVAFTPQNVYGVLSILFWTLTTIVSLKYVVLVLRADNNGEGG
LIAMLALASQAVKDKPRLRSALLGIGVFGTSLFYGDGVITPAISVLSAVEGLEVVSPHFGKAVIPLTLIVLFCLFAVQKR
GTSGIGRYFGPVTLVWFTSIAALGVPHIVGHPEILGALSPHHALGFIWRSPGTSFIILGAVVLCVTGAEALYADLGHFGK
KPIRLAWFSVAMPALTINYFGQGALLLAEPEAVKNPFYMMAPDWALIPLVIMATMATVIASQALITGAFSVTKQVIQLGY
LPRLNILHTSVRDTGQIYIPFVNWALFLAIVLAVVMFRSSSNLAAAYGIAVTLDMLITTVLTFFVIRYGWRYPLALCIAA
TGFFFLVDLAFFGSNLLKLLQGGWFPLMIGSIVFMLMMTWKRGRELLNEKLRADAIDLRDFLTAVFVNPPTRVDGTAVFL
TAEPGAVPNALLHNLKHNKVLHQQNLFVTVRNHEVPWIGLDKRLQVEALGGDCWQVMVHYGFKNDPDLPGALALMRGRGC
ELESMTTSYFLSRDVVTPTIGSGMAPWREKLFAQMHHNASGAAGFLNLPSNSVVELGSKIEI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=628, Percent_Identity=47.7707006369427, Blast_Score=585, Evalue=1e-168,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_ACIAC (A1TVU0)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_972852.1
- ProteinModelPortal:   A1TVU0
- STRING:   A1TVU0
- GeneID:   4668383
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_4541
- NMPDR:   fig|397945.5.peg.3910
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   FVIRYSW
- PhylomeDB:   A1TVU0
- ProtClustDB:   CLSK951078
- BioCyc:   AAVE397945:AAVE_4541-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 67381; Mature: 67381

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16efb570)-; HASH(0x1869af84)-; HASH(0x18a20000)-; HASH(0x18b3e83c)-; HASH(0x18ae40b8)-; HASH(0x1803ec44)-; HASH(0x18a26148)-; HASH(0x13b432c8)-; HASH(0x17406fb0)-; HASH(0x185c4f9c)-; HASH(0x18bfd154)-; HASH(0x18be7184)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRSKSSLAALTLGAIGVVYGDIGTSVLYAVKEVFGSGHVAFTPQNVYGVLSILFWTLTT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHH
IVSLKYVVLVLRADNNGEGGLIAMLALASQAVKDKPRLRSALLGIGVFGTSLFYGDGVIT
HHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
PAISVLSAVEGLEVVSPHFGKAVIPLTLIVLFCLFAVQKRGTSGIGRYFGPVTLVWFTSI
HHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AALGVPHIVGHPEILGALSPHHALGFIWRSPGTSFIILGAVVLCVTGAEALYADLGHFGK
HHHCCCCCCCCHHHHHCCCCCHHEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCC
KPIRLAWFSVAMPALTINYFGQGALLLAEPEAVKNPFYMMAPDWALIPLVIMATMATVIA
CCCEEHHHHHHHHHHEEEECCCCEEEEECCHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
SQALITGAFSVTKQVIQLGYLPRLNILHTSVRDTGQIYIPFVNWALFLAIVLAVVMFRSS
HHHHHHHHHHHHHHHHHHCCCCCCHHHECCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCC
SNLAAAYGIAVTLDMLITTVLTFFVIRYGWRYPLALCIAATGFFFLVDLAFFGSNLLKLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGGWFPLMIGSIVFMLMMTWKRGRELLNEKLRADAIDLRDFLTAVFVNPPTRVDGTAVFL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
TAEPGAVPNALLHNLKHNKVLHQQNLFVTVRNHEVPWIGLDKRLQVEALGGDCWQVMVHY
EECCCCCHHHHHHHHHHHHEEEECCEEEEEECCCCCEEECCCCEEEEECCCHHHHHHHHC
GFKNDPDLPGALALMRGRGCELESMTTSYFLSRDVVTPTIGSGMAPWREKLFAQMHHNAS
CCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCC
GAAGFLNLPSNSVVELGSKIEI
CCCEEEECCCCHHHHCCCCCCH
>Mature Secondary Structure
MQRSKSSLAALTLGAIGVVYGDIGTSVLYAVKEVFGSGHVAFTPQNVYGVLSILFWTLTT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHH
IVSLKYVVLVLRADNNGEGGLIAMLALASQAVKDKPRLRSALLGIGVFGTSLFYGDGVIT
HHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
PAISVLSAVEGLEVVSPHFGKAVIPLTLIVLFCLFAVQKRGTSGIGRYFGPVTLVWFTSI
HHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AALGVPHIVGHPEILGALSPHHALGFIWRSPGTSFIILGAVVLCVTGAEALYADLGHFGK
HHHCCCCCCCCHHHHHCCCCCHHEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCC
KPIRLAWFSVAMPALTINYFGQGALLLAEPEAVKNPFYMMAPDWALIPLVIMATMATVIA
CCCEEHHHHHHHHHHEEEECCCCEEEEECCHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
SQALITGAFSVTKQVIQLGYLPRLNILHTSVRDTGQIYIPFVNWALFLAIVLAVVMFRSS
HHHHHHHHHHHHHHHHHHCCCCCCHHHECCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCC
SNLAAAYGIAVTLDMLITTVLTFFVIRYGWRYPLALCIAATGFFFLVDLAFFGSNLLKLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGGWFPLMIGSIVFMLMMTWKRGRELLNEKLRADAIDLRDFLTAVFVNPPTRVDGTAVFL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
TAEPGAVPNALLHNLKHNKVLHQQNLFVTVRNHEVPWIGLDKRLQVEALGGDCWQVMVHY
EECCCCCHHHHHHHHHHHHEEEECCEEEEEECCCCCEEECCCCEEEEECCCHHHHHHHHC
GFKNDPDLPGALALMRGRGCELESMTTSYFLSRDVVTPTIGSGMAPWREKLFAQMHHNAS
CCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCC
GAAGFLNLPSNSVVELGSKIEI
CCCEEEECCCCHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA