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The map label for this gene is ligD [H]

Identifier: 120611532

GI number: 120611532

Start: 3159130

End: 3160035

Strand: Reverse

Name: ligD [H]

Synonym: Aave_2868

Alternate gene names: 120611532

Gene position: 3160035-3159130 (Counterclockwise)

Preceding gene: 120611533

Following gene: 120611527

Centisome position: 59.04

GC content: 70.31

Gene sequence:

>906_bases
ATGATCGAAGACTTCCAGGGCAAGACCGCCGTGCTCACCGGCGCGGGATCGGGATTCGGACTCGAATGCGCCCGCATCGG
CGCGCGGCGCGGCATGCGCCTCGTGCTGGTCGATGTGCAGCAGGACGCGCTGGACCAGGCCGAGGCCGAGGTCCGGGCCG
CCGGTGCCGACGTGCTGGCCAGGCGCGTGGACGTGGCCGACGCCGGGCAGATGGAACGCCTCGCGTCCGACGTCCGGGAC
CGTTTCGGCGCACCGCATTTCGTCTTCAACAATGCCGGTGTGGGAGCCGGGGGCCTGGTCTGGGAGAACACCGTCGCCGA
CTGGAACTGGGTGCTCGGCGTGAACCTCATGGGCGTGGTGCATGGCGTGCGCCTCTTCACGCCCATGATGCTCGATGCCG
CGCGGCAGGATCCCGCCTGGCGCGGCCACATCGTCAACACCGCCAGCATGGCCGGCCTGCTCACGCCCCCGAACATGGGC
ATCTACAACGTGAGCAAGCACGCCGTGGTGAGCCTCACCGAAACCCTGTACCAGGACCTGGCCCTGGTCACGGACCAGGT
CGGCGCCAGCGTGCTCTGCCCGTATTTCGTCCCCACGGGCATCGGCCGCAGCGAGCGCAACCGGCCCGATGCGGTGGCCG
CGCCCCCCACGCGCAGCCAGCTCATCGGCCAGGCCATGACCGACAAGGCCGTGGGCAGCGGCAAGGTCACGGCCGCCGAG
GTGGCGCAGATGGTGTTCGACGGCATCTCCGCCAACCGCTTCTACCTCTTCAGCCACCCCCAGGCGCTGGGCAACGTGCA
AAGCCGCATGGAAAGCATCGTGGGCGTCCGCAACCCGCCGGACCCGTTCCTCGAGCGCCCCGACATCGGCCGGCGCCTGC
GCGAGCAGTTGCGCGCGCCGGCCTGA

Upstream 100 bases:

>100_bases
CGCGCTACACGCTGGCACGCACCGACCCGCGCGCGGGCACGCTCCACGTGCATTTCCCGCGCATCGGCTACACGCTCACT
TCCACGGAGACAACCACACC

Downstream 100 bases:

>100_bases
CTCCCGCACCCGGTGTTGCCCTGGCGGTTGCCGGGGCATGGGGAACGGGCAACCACGGTCAGACGGCGCGCAGCGGGACC
CCGCGCAGCCCCTTCAGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIEDFQGKTAVLTGAGSGFGLECARIGARRGMRLVLVDVQQDALDQAEAEVRAAGADVLARRVDVADAGQMERLASDVRD
RFGAPHFVFNNAGVGAGGLVWENTVADWNWVLGVNLMGVVHGVRLFTPMMLDAARQDPAWRGHIVNTASMAGLLTPPNMG
IYNVSKHAVVSLTETLYQDLALVTDQVGASVLCPYFVPTGIGRSERNRPDAVAAPPTRSQLIGQAMTDKAVGSGKVTAAE
VAQMVFDGISANRFYLFSHPQALGNVQSRMESIVGVRNPPDPFLERPDIGRRLREQLRAPA

Sequences:

>Translated_301_residues
MIEDFQGKTAVLTGAGSGFGLECARIGARRGMRLVLVDVQQDALDQAEAEVRAAGADVLARRVDVADAGQMERLASDVRD
RFGAPHFVFNNAGVGAGGLVWENTVADWNWVLGVNLMGVVHGVRLFTPMMLDAARQDPAWRGHIVNTASMAGLLTPPNMG
IYNVSKHAVVSLTETLYQDLALVTDQVGASVLCPYFVPTGIGRSERNRPDAVAAPPTRSQLIGQAMTDKAVGSGKVTAAE
VAQMVFDGISANRFYLFSHPQALGNVQSRMESIVGVRNPPDPFLERPDIGRRLREQLRAPA
>Mature_301_residues
MIEDFQGKTAVLTGAGSGFGLECARIGARRGMRLVLVDVQQDALDQAEAEVRAAGADVLARRVDVADAGQMERLASDVRD
RFGAPHFVFNNAGVGAGGLVWENTVADWNWVLGVNLMGVVHGVRLFTPMMLDAARQDPAWRGHIVNTASMAGLLTPPNMG
IYNVSKHAVVSLTETLYQDLALVTDQVGASVLCPYFVPTGIGRSERNRPDAVAAPPTRSQLIGQAMTDKAVGSGKVTAAE
VAQMVFDGISANRFYLFSHPQALGNVQSRMESIVGVRNPPDPFLERPDIGRRLREQLRAPA

Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=31.5, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI142976729, Length=199, Percent_Identity=30.1507537688442, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI210032110, Length=203, Percent_Identity=29.064039408867, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI25282469, Length=248, Percent_Identity=28.2258064516129, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI310128830, Length=206, Percent_Identity=27.1844660194175, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI310115468, Length=206, Percent_Identity=27.1844660194175, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=29.2929292929293, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=202, Percent_Identity=25.2475247524752, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI83715985, Length=182, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4758504, Length=182, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=201, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082160, Length=206, Percent_Identity=25.2427184466019, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787335, Length=215, Percent_Identity=24.6511627906977, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=27.5, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=199, Percent_Identity=29.6482412060301, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=201, Percent_Identity=29.3532338308458, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=26.9035532994924, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=228, Percent_Identity=28.0701754385965, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=249, Percent_Identity=28.1124497991968, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=269, Percent_Identity=25.2788104089219, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24581726, Length=216, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640492, Length=209, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281364892, Length=207, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364494, Length=209, Percent_Identity=28.2296650717703, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355631, Length=200, Percent_Identity=27.5, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644339, Length=179, Percent_Identity=28.4916201117318, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648944, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=176, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357041, Length=179, Percent_Identity=28.4916201117318, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571526, Length=181, Percent_Identity=27.6243093922652, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571387, Length=212, Percent_Identity=27.3584905660377, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859837, Length=216, Percent_Identity=28.7037037037037, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007236, Length=208, Percent_Identity=26.4423076923077, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32317; Mature: 32317

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEDFQGKTAVLTGAGSGFGLECARIGARRGMRLVLVDVQQDALDQAEAEVRAAGADVLA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
RRVDVADAGQMERLASDVRDRFGAPHFVFNNAGVGAGGLVWENTVADWNWVLGVNLMGVV
HHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
HGVRLFTPMMLDAARQDPAWRGHIVNTASMAGLLTPPNMGIYNVSKHAVVSLTETLYQDL
HHHHHHHHHHHHHHHCCCCCCCEEECHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHH
ALVTDQVGASVLCPYFVPTGIGRSERNRPDAVAAPPTRSQLIGQAMTDKAVGSGKVTAAE
HHHHHHHCHHEECHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
VAQMVFDGISANRFYLFSHPQALGNVQSRMESIVGVRNPPDPFLERPDIGRRLREQLRAP
HHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
A
C
>Mature Secondary Structure
MIEDFQGKTAVLTGAGSGFGLECARIGARRGMRLVLVDVQQDALDQAEAEVRAAGADVLA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
RRVDVADAGQMERLASDVRDRFGAPHFVFNNAGVGAGGLVWENTVADWNWVLGVNLMGVV
HHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
HGVRLFTPMMLDAARQDPAWRGHIVNTASMAGLLTPPNMGIYNVSKHAVVSLTETLYQDL
HHHHHHHHHHHHHHHCCCCCCCEEECHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHH
ALVTDQVGASVLCPYFVPTGIGRSERNRPDAVAAPPTRSQLIGQAMTDKAVGSGKVTAAE
HHHHHHHCHHEECHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
VAQMVFDGISANRFYLFSHPQALGNVQSRMESIVGVRNPPDPFLERPDIGRRLREQLRAP
HHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744051; 8495726; 7764263 [H]