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The map label for this gene is lytS [H]

Identifier: 120610715

GI number: 120610715

Start: 2217118

End: 2218233

Strand: Reverse

Name: lytS [H]

Synonym: Aave_2036

Alternate gene names: 120610715

Gene position: 2218233-2217118 (Counterclockwise)

Preceding gene: 120610723

Following gene: 120610714

Centisome position: 41.44

GC content: 73.39

Gene sequence:

>1116_bases
ATGCCGCCCACTACACCGCGCCACCTCGTCCGCCACGGCCTGCTCGTGGCCGCCTTCTGCTGCGCCATCGCCGCGATCCA
GGTGGCCTACGGCCGGGGGCCCTGGCATGCACAGGCGGTGTATTCGCTCTCGATCGGCCTGAGCAGCTGGCTGCTCATCG
AGGCGGGCCGGTTCTGGCTCACGCGCCGCAGCCCCATTCCCTGGCCGTTGGGCTGGCGCGGCTGGGCGCTGGTGGCCGCT
GGCGGCACGATCGGCTTCCAGGTCGGCTCGGCCATCGGCGACGCCTACTGCAGCGCCATCGGCCTGACGCGACCGGTCTC
TCCGTCGCCGGGCGCCCCGGGCCCGGCGGTCATCACGACGATGCTCGCCTGCCTGGCGATCTCGCTCTTCTTCTACGCGC
AGGGCAAGGCGCGCTACCTGGAAGGCCGCATCGCCGAGGCGCAGCGGGACGCGGCCGAGGCGCGGCTGCGGCTGCTGCAG
ACGCAGCTGGAGCCGCACATGATGTTCAACACCCTGGCCAACCTGCGCATGCTCATCGCGGCCGACCCATTGCGCGCACA
GGCCATGCTGGACCACTTCATCGCCTACCTGCGCGCCACCCTGGGCGCTTCGCGCGCGACCGCGCATCCGCTGGTCGACG
AGTTCGAACTGCTGCGCGATTACCTGGAACTCATGTCCGTGCGCATGGGCGCGCGGCTGGCGTACACAATCGACCTGCCC
GCGCCGCTGCGCGACGTGCCCGTGCCGCCCCTGCTGCTGCAGCCGCTGGTGGAAAACGCCATCCGCCACGGGCTGGAGCC
GCAGGTGGAAGGCGGACGCATCACGGTGGCCGCGCGCACGCTGCCCGGCGCGCCCGACCGGCTGGAGCTGGCCGTCCACG
ACACCGGCGCGGGGCTGGGCGAGCTTCCCGTGCAGCCCGGCAGCCGCTTCGGCCTCGCCCAGGTGCGCGAACGCCTCGCC
ACACTGCGGGGACCGGCGGCCATGCTGGAGCTGGGCCCGGGCGACGGCGGCCGCGGCACGCGGGTGCGCATCGTCCTTCC
GCTGGAAAGGTCGGCCGCGGCCGCATCCACCACCCCTTTGACCGGACCGCCGCCATGCACGCCCCCCGCGCCCTGA

Upstream 100 bases:

>100_bases
CGAACCTCTACCGCCGCCTGCTGGAACGCGAACGCGCCGCGCTGCGCCGCCGCGTGTGACCGGCACCACGGCCGGGGCGC
ACAATCGGGGCGGAGTGCCC

Downstream 100 bases:

>100_bases
TCGCCGAAGACGAACCGCTGCTGGCGCAAGCCCTGCGCCAGGAACTCGCGCGGGCCTGGCCCGGGCTGCAGATCGCCGCG
ACCGTCGGCGACGGCCGCAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MPPTTPRHLVRHGLLVAAFCCAIAAIQVAYGRGPWHAQAVYSLSIGLSSWLLIEAGRFWLTRRSPIPWPLGWRGWALVAA
GGTIGFQVGSAIGDAYCSAIGLTRPVSPSPGAPGPAVITTMLACLAISLFFYAQGKARYLEGRIAEAQRDAAEARLRLLQ
TQLEPHMMFNTLANLRMLIAADPLRAQAMLDHFIAYLRATLGASRATAHPLVDEFELLRDYLELMSVRMGARLAYTIDLP
APLRDVPVPPLLLQPLVENAIRHGLEPQVEGGRITVAARTLPGAPDRLELAVHDTGAGLGELPVQPGSRFGLAQVRERLA
TLRGPAAMLELGPGDGGRGTRVRIVLPLERSAAAASTTPLTGPPPCTPPAP

Sequences:

>Translated_371_residues
MPPTTPRHLVRHGLLVAAFCCAIAAIQVAYGRGPWHAQAVYSLSIGLSSWLLIEAGRFWLTRRSPIPWPLGWRGWALVAA
GGTIGFQVGSAIGDAYCSAIGLTRPVSPSPGAPGPAVITTMLACLAISLFFYAQGKARYLEGRIAEAQRDAAEARLRLLQ
TQLEPHMMFNTLANLRMLIAADPLRAQAMLDHFIAYLRATLGASRATAHPLVDEFELLRDYLELMSVRMGARLAYTIDLP
APLRDVPVPPLLLQPLVENAIRHGLEPQVEGGRITVAARTLPGAPDRLELAVHDTGAGLGELPVQPGSRFGLAQVRERLA
TLRGPAAMLELGPGDGGRGTRVRIVLPLERSAAAASTTPLTGPPPCTPPAP
>Mature_370_residues
PPTTPRHLVRHGLLVAAFCCAIAAIQVAYGRGPWHAQAVYSLSIGLSSWLLIEAGRFWLTRRSPIPWPLGWRGWALVAAG
GTIGFQVGSAIGDAYCSAIGLTRPVSPSPGAPGPAVITTMLACLAISLFFYAQGKARYLEGRIAEAQRDAAEARLRLLQT
QLEPHMMFNTLANLRMLIAADPLRAQAMLDHFIAYLRATLGASRATAHPLVDEFELLRDYLELMSVRMGARLAYTIDLPA
PLRDVPVPPLLLQPLVENAIRHGLEPQVEGGRITVAARTLPGAPDRLELAVHDTGAGLGELPVQPGSRFGLAQVRERLAT
LRGPAAMLELGPGDGGRGTRVRIVLPLERSAAAASTTPLTGPPPCTPPAP

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=252, Percent_Identity=30.1587301587302, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788446, Length=191, Percent_Identity=31.413612565445, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39605; Mature: 39474

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTTPRHLVRHGLLVAAFCCAIAAIQVAYGRGPWHAQAVYSLSIGLSSWLLIEAGRFWL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEHHCCHHEEEEECCCEEE
TRRSPIPWPLGWRGWALVAAGGTIGFQVGSAIGDAYCSAIGLTRPVSPSPGAPGPAVITT
EECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
MLACLAISLFFYAQGKARYLEGRIAEAQRDAAEARLRLLQTQLEPHMMFNTLANLRMLIA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEE
ADPLRAQAMLDHFIAYLRATLGASRATAHPLVDEFELLRDYLELMSVRMGARLAYTIDLP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
APLRDVPVPPLLLQPLVENAIRHGLEPQVEGGRITVAARTLPGAPDRLELAVHDTGAGLG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCC
ELPVQPGSRFGLAQVRERLATLRGPAAMLELGPGDGGRGTRVRIVLPLERSAAAASTTPL
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCC
TGPPPCTPPAP
CCCCCCCCCCC
>Mature Secondary Structure 
PPTTPRHLVRHGLLVAAFCCAIAAIQVAYGRGPWHAQAVYSLSIGLSSWLLIEAGRFWL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEHHCCHHEEEEECCCEEE
TRRSPIPWPLGWRGWALVAAGGTIGFQVGSAIGDAYCSAIGLTRPVSPSPGAPGPAVITT
EECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
MLACLAISLFFYAQGKARYLEGRIAEAQRDAAEARLRLLQTQLEPHMMFNTLANLRMLIA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEE
ADPLRAQAMLDHFIAYLRATLGASRATAHPLVDEFELLRDYLELMSVRMGARLAYTIDLP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
APLRDVPVPPLLLQPLVENAIRHGLEPQVEGGRITVAARTLPGAPDRLELAVHDTGAGLG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCC
ELPVQPGSRFGLAQVRERLATLRGPAAMLELGPGDGGRGTRVRIVLPLERSAAAASTTPL
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCC
TGPPPCTPPAP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]