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The map label for this gene is frr

Identifier: 120610506

GI number: 120610506

Start: 1980258

End: 1980818

Strand: Direct

Name: frr

Synonym: Aave_1826

Alternate gene names: 120610506

Gene position: 1980258-1980818 (Clockwise)

Preceding gene: 120610505

Following gene: 120610507

Centisome position: 36.99

GC content: 63.28

Gene sequence:

>561_bases
ATGACGATTGCCGACATCAAGAAAAACACCGAAGCCAAGATGGACCAGTCCATCGTGGCCTTCAAGAACAATCTCGCCAA
GATCCGCACCGGCCGTGCGAATCCGGCGCTGCTCGACTCCGTCCAGGTCGAGTACTACGGCTCCATGGTGCCGCTGTCGC
AGGTGGCGAACGTGTCGCTGATCGACGCGCGCACCATCAGCGTCCAGCCCTGGGAAAAGGGCATGGGCGCCAAGATCGAG
AAGGCCATCCGCGAAAGCGAGCTGGGCCTGAACCCCGCCTCCATGGGCGACCTCATCCGCGTGCCGATGCCGCCGATGAG
CGAGGAGCGCCGCAAGGAGATGACCAAGCTCGCGCGCAACGAAGGCGAGGGCGCCAAGGTGGCCGTGCGCAACCTGCGCC
GCGACGCCAACGAATCGGTCAAGAAGCTCGTGAAGGACAAGCTCGCTTCCGAGGACGAGCAGAAGCGCGCCGAAGCCGAC
ATCCAGAAGGTGACCGACAAGCACATCGCCGAAGTCGATGCGCTCGTGGCCGCCAAGGAACAGGAAATCATGGCGGTCTG
A

Upstream 100 bases:

>100_bases
GAGGACGAAGGAACGCTGGTGTACGCTTGACGCCCGACTGCACCGTGCCCGCGGCGGCTTGGCGCCGACCCGGGCGACGG
ATGCGCGCACAGGAGAACAC

Downstream 100 bases:

>100_bases
TCGGCCCGTTGCACGGGTTCGATCGATGCCTTCCATGTCCGCCGCCTCGCCAGCCGTCCCCCACCACGTCGCCATCGTCA
TGGATGGCAATGGCCGGTGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTIADIKKNTEAKMDQSIVAFKNNLAKIRTGRANPALLDSVQVEYYGSMVPLSQVANVSLIDARTISVQPWEKGMGAKIE
KAIRESELGLNPASMGDLIRVPMPPMSEERRKEMTKLARNEGEGAKVAVRNLRRDANESVKKLVKDKLASEDEQKRAEAD
IQKVTDKHIAEVDALVAAKEQEIMAV

Sequences:

>Translated_186_residues
MTIADIKKNTEAKMDQSIVAFKNNLAKIRTGRANPALLDSVQVEYYGSMVPLSQVANVSLIDARTISVQPWEKGMGAKIE
KAIRESELGLNPASMGDLIRVPMPPMSEERRKEMTKLARNEGEGAKVAVRNLRRDANESVKKLVKDKLASEDEQKRAEAD
IQKVTDKHIAEVDALVAAKEQEIMAV
>Mature_185_residues
TIADIKKNTEAKMDQSIVAFKNNLAKIRTGRANPALLDSVQVEYYGSMVPLSQVANVSLIDARTISVQPWEKGMGAKIEK
AIRESELGLNPASMGDLIRVPMPPMSEERRKEMTKLARNEGEGAKVAVRNLRRDANESVKKLVKDKLASEDEQKRAEADI
QKVTDKHIAEVDALVAAKEQEIMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=33.9080459770115, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=34, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=52.7472527472528, Blast_Score=207, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=26.5536723163842, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_ACIAC (A1TN72)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970184.1
- ProteinModelPortal:   A1TN72
- SMR:   A1TN72
- STRING:   A1TN72
- GeneID:   4665181
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1826
- NMPDR:   fig|397945.5.peg.1580
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   A1TN72
- ProtClustDB:   PRK00083
- BioCyc:   AAVE397945:AAVE_1826-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20570; Mature: 20439

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIADIKKNTEAKMDQSIVAFKNNLAKIRTGRANPALLDSVQVEYYGSMVPLSQVANVSL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHCCEEE
IDARTISVQPWEKGMGAKIEKAIRESELGLNPASMGDLIRVPMPPMSEERRKEMTKLARN
ECCEEEECCCHHCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHC
EGEGAKVAVRNLRRDANESVKKLVKDKLASEDEQKRAEADIQKVTDKHIAEVDALVAAKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEIMAV
HHHHCC
>Mature Secondary Structure 
TIADIKKNTEAKMDQSIVAFKNNLAKIRTGRANPALLDSVQVEYYGSMVPLSQVANVSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHCCEEE
IDARTISVQPWEKGMGAKIEKAIRESELGLNPASMGDLIRVPMPPMSEERRKEMTKLARN
ECCEEEECCCHHCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHC
EGEGAKVAVRNLRRDANESVKKLVKDKLASEDEQKRAEADIQKVTDKHIAEVDALVAAKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEIMAV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA