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The map label for this gene is yfhA [H]

Identifier: 120609566

GI number: 120609566

Start: 947668

End: 949083

Strand: Reverse

Name: yfhA [H]

Synonym: Aave_0872

Alternate gene names: 120609566

Gene position: 949083-947668 (Counterclockwise)

Preceding gene: 120609567

Following gene: 120609565

Centisome position: 17.73

GC content: 71.26

Gene sequence:

>1416_bases
ATGCCCGCCACGCCCCCGACGAAAACCTCCGCGCCCCGTCCACGCATCCTCGTGGTGGACGACGATGCCGACATGCTGCG
GCTGCTGTCGCTGCGACTCAACGCGGCCGGCTACGAAATCACGGCCGTCCCCTCCGCCGAAGCCGCGCTCGCCCAGCTGG
AAACCAGCCGCCCGCAGCTCGTGCTGAGCGACGTGCGCCTGCCCGGCCGCGACGGCCTGGCCCTGTTCGACGAGGTGCGC
TCGCGCCATCCTTCGCTGCCCGTGATCCTGCTCACCGCGCACGGCACCATCCCCGACGCGGTCGAGGCCACGGCGCGCGG
CGTGTTCACCTACCTCACCAAGCCCTACGACGCCAAGGACCTGCTCGACAAGATCGCGCAGGCCCTGGCGCTGAGCGCGC
CCGCCACGCAGACGCCCCAGGCCGACAGCACCTGGCGCGCCGAGATCGTGAGCCGCTCCAACCGCATGGCCGACCTGCTC
GCCGAGGCCCGCATGGTGGCCCAGTCGGACGCCAGCGTGCTGCTGCTGGGCGACAGCGGCACCGGCAAGGAACTGCTGGC
GCGCGCCATCCACCGGGCCAGCCCGCGCGCGGCGCGGCCCTTCGTGGCCGTCAATTGCGGCGCCATCCCCGAGGCCCTGC
TGGAGTCCGAACTGTTCGGCCACATGAAGGGCGCCTTCACCGACGCGCACAGCAACCACAAGGGCCTGTTCCAGGCGGCC
GACGGCGGCACGCTGCTGCTCGACGAAATCGGCGACATGCCGCCCGCGCTGCAGGTCAAGCTGCTGCGCGTGCTGCAGGA
GCGCGCCGTGCGCCCCGTCGGCGCGAGCCAGGCCACGCCGGTGAACGTGCGCATCGTCTCCGCCACGCACCGCGACCTGG
AGGCCGCCATGGCCACGGGCCAGTTCCGCGAGGACCTCTACTACCGCCTCAACGTGGTCACGCTGACGCTGCCCACCCTG
GCCGACCGCCGCGAGGACATCCCGCTACTGGCCAACCATTTCCTCGACCAGCTGGCGCGCAAGTACGACAAGCGCCTGTC
GGGCTTTTCGCCGGAAGCGCTCAAGGCGCTCACGGCGGCGCCCTGGCCAGGCAACGTGCGGCAGCTCTACAACGTGGTGG
AGCAGGCCTGCGCGCTCTCCACCACGCCCCTGGTACCGCTGGGCCTCGTGCAGCGCGCGCTGCGCACGCCCACCGTGCAG
GTGCTGAGCTTCACCGAGGCGCGCCAGCGCTTCGAGCGCGAATACCTGGTGGACCTGCTGAAGATGACCGACGGCAACGT
CGCCGATGCCGCGCGGCTGGCGCAGCGCAACCGTACGGAGTTCTACCGCCTGCTGCAGAAGCACGCGCTGACGCCGGGCC
AGTTCAAGAGCGACGGGGCCCCGCCGGACGATGTCGCCGAAGAGCGACAACAATAA

Upstream 100 bases:

>100_bases
GCCATCGAGCGCAGCCTCAATGCCCGCCCGGGCGCCCCCGGCAACGGCCGGGCCGCGCACCCCGCACCGACCGAATCCCC
CCGCTGAACCGGCCCCGAGC

Downstream 100 bases:

>100_bases
AGCGTTGATTTCAAAGGATTTTTCCTTTTCGACCGCCTCTCCGGTCGCTGGTTCGCGACAAAAACCGGGGTTTCGGGGCC
TTCCAGAGGCTCCGCACAAC

Product: Fis family two component sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MPATPPTKTSAPRPRILVVDDDADMLRLLSLRLNAAGYEITAVPSAEAALAQLETSRPQLVLSDVRLPGRDGLALFDEVR
SRHPSLPVILLTAHGTIPDAVEATARGVFTYLTKPYDAKDLLDKIAQALALSAPATQTPQADSTWRAEIVSRSNRMADLL
AEARMVAQSDASVLLLGDSGTGKELLARAIHRASPRAARPFVAVNCGAIPEALLESELFGHMKGAFTDAHSNHKGLFQAA
DGGTLLLDEIGDMPPALQVKLLRVLQERAVRPVGASQATPVNVRIVSATHRDLEAAMATGQFREDLYYRLNVVTLTLPTL
ADRREDIPLLANHFLDQLARKYDKRLSGFSPEALKALTAAPWPGNVRQLYNVVEQACALSTTPLVPLGLVQRALRTPTVQ
VLSFTEARQRFEREYLVDLLKMTDGNVADAARLAQRNRTEFYRLLQKHALTPGQFKSDGAPPDDVAEERQQ

Sequences:

>Translated_471_residues
MPATPPTKTSAPRPRILVVDDDADMLRLLSLRLNAAGYEITAVPSAEAALAQLETSRPQLVLSDVRLPGRDGLALFDEVR
SRHPSLPVILLTAHGTIPDAVEATARGVFTYLTKPYDAKDLLDKIAQALALSAPATQTPQADSTWRAEIVSRSNRMADLL
AEARMVAQSDASVLLLGDSGTGKELLARAIHRASPRAARPFVAVNCGAIPEALLESELFGHMKGAFTDAHSNHKGLFQAA
DGGTLLLDEIGDMPPALQVKLLRVLQERAVRPVGASQATPVNVRIVSATHRDLEAAMATGQFREDLYYRLNVVTLTLPTL
ADRREDIPLLANHFLDQLARKYDKRLSGFSPEALKALTAAPWPGNVRQLYNVVEQACALSTTPLVPLGLVQRALRTPTVQ
VLSFTEARQRFEREYLVDLLKMTDGNVADAARLAQRNRTEFYRLLQKHALTPGQFKSDGAPPDDVAEERQQ
>Mature_470_residues
PATPPTKTSAPRPRILVVDDDADMLRLLSLRLNAAGYEITAVPSAEAALAQLETSRPQLVLSDVRLPGRDGLALFDEVRS
RHPSLPVILLTAHGTIPDAVEATARGVFTYLTKPYDAKDLLDKIAQALALSAPATQTPQADSTWRAEIVSRSNRMADLLA
EARMVAQSDASVLLLGDSGTGKELLARAIHRASPRAARPFVAVNCGAIPEALLESELFGHMKGAFTDAHSNHKGLFQAAD
GGTLLLDEIGDMPPALQVKLLRVLQERAVRPVGASQATPVNVRIVSATHRDLEAAMATGQFREDLYYRLNVVTLTLPTLA
DRREDIPLLANHFLDQLARKYDKRLSGFSPEALKALTAAPWPGNVRQLYNVVEQACALSTTPLVPLGLVQRALRTPTVQV
LSFTEARQRFEREYLVDLLKMTDGNVADAARLAQRNRTEFYRLLQKHALTPGQFKSDGAPPDDVAEERQQ

Specific function: Probable member of a two-component regulatory system yfhA/yfhK [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=441, Percent_Identity=57.3696145124717, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=42.6048565121413, Blast_Score=352, Evalue=4e-98,
Organism=Escherichia coli, GI1790437, Length=432, Percent_Identity=44.6759259259259, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1790299, Length=472, Percent_Identity=41.3135593220339, Blast_Score=318, Evalue=7e-88,
Organism=Escherichia coli, GI87082117, Length=315, Percent_Identity=48.2539682539683, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1789087, Length=307, Percent_Identity=44.9511400651466, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1789233, Length=210, Percent_Identity=53.8095238095238, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082152, Length=331, Percent_Identity=39.2749244712991, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786524, Length=386, Percent_Identity=37.5647668393782, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1787583, Length=302, Percent_Identity=40.0662251655629, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI87081872, Length=325, Percent_Identity=37.8461538461538, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87081858, Length=304, Percent_Identity=31.5789473684211, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789828, Length=251, Percent_Identity=35.8565737051793, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1789809, Length=135, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788394, Length=130, Percent_Identity=31.5384615384615, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787375, Length=115, Percent_Identity=33.9130434782609, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790552, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51365; Mature: 51234

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATPPTKTSAPRPRILVVDDDADMLRLLSLRLNAAGYEITAVPSAEAALAQLETSRPQL
CCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCE
VLSDVRLPGRDGLALFDEVRSRHPSLPVILLTAHGTIPDAVEATARGVFTYLTKPYDAKD
EEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHH
LLDKIAQALALSAPATQTPQADSTWRAEIVSRSNRMADLLAEARMVAQSDASVLLLGDSG
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
TGKELLARAIHRASPRAARPFVAVNCGAIPEALLESELFGHMKGAFTDAHSNHKGLFQAA
CCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
DGGTLLLDEIGDMPPALQVKLLRVLQERAVRPVGASQATPVNVRIVSATHRDLEAAMATG
CCCEEEHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHH
QFREDLYYRLNVVTLTLPTLADRREDIPLLANHFLDQLARKYDKRLSGFSPEALKALTAA
HHHHHHHEEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
PWPGNVRQLYNVVEQACALSTTPLVPLGLVQRALRTPTVQVLSFTEARQRFEREYLVDLL
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
KMTDGNVADAARLAQRNRTEFYRLLQKHALTPGQFKSDGAPPDDVAEERQQ
HHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
PATPPTKTSAPRPRILVVDDDADMLRLLSLRLNAAGYEITAVPSAEAALAQLETSRPQL
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCE
VLSDVRLPGRDGLALFDEVRSRHPSLPVILLTAHGTIPDAVEATARGVFTYLTKPYDAKD
EEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHH
LLDKIAQALALSAPATQTPQADSTWRAEIVSRSNRMADLLAEARMVAQSDASVLLLGDSG
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
TGKELLARAIHRASPRAARPFVAVNCGAIPEALLESELFGHMKGAFTDAHSNHKGLFQAA
CCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
DGGTLLLDEIGDMPPALQVKLLRVLQERAVRPVGASQATPVNVRIVSATHRDLEAAMATG
CCCEEEHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHH
QFREDLYYRLNVVTLTLPTLADRREDIPLLANHFLDQLARKYDKRLSGFSPEALKALTAA
HHHHHHHEEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
PWPGNVRQLYNVVEQACALSTTPLVPLGLVQRALRTPTVQVLSFTEARQRFEREYLVDLL
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
KMTDGNVADAARLAQRNRTEFYRLLQKHALTPGQFKSDGAPPDDVAEERQQ
HHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]