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The map label for this gene is thiL [H]

Identifier: 120609135

GI number: 120609135

Start: 467341

End: 468321

Strand: Reverse

Name: thiL [H]

Synonym: Aave_0432

Alternate gene names: 120609135

Gene position: 468321-467341 (Counterclockwise)

Preceding gene: 120609137

Following gene: 120609134

Centisome position: 8.75

GC content: 73.5

Gene sequence:

>981_bases
ATGGGTGAATTCGATCTGATCGCGCGCTATTTCCGCCGCCCCGTGCGCCGCGCGGCCCTGGGCGTGGGCGACGACTGCGC
GCTGCTTGCGCCGGCCGCCGGCATGCAGCTCGCGGTGTCCAGCGACATGCTGGTGGAAGGCCGGCACTTCTTCGCCGATG
TCTACCCCGCGCACCTGGGCCACAAGGCCCTGGCGGTGAACCTGTCGGATCTCGCGGCCTGCGGCGCGCGCCCTCTGGCC
TTCACGCTGGCGCTGGCGCTGCCCCGCGCCGACGAGGTCTGGCTGCAGGGCTTCTCGGAAGGCCTGCTGGCCCTGGCAGG
CGAACATGGCTGCGAACTGGTGGGCGGGGACACCACGCAAGGCCCGCTCAACATCTGCATCACGGTGTTCGGCGAAGTGC
CCGCGGGCCAGGCCCTGCTGCGCAGCGGCGCCCGCCCGGGCGACGACCTGTGGGTGAGCGGCCACCTGGGCGATGCGCGG
CTGGCACTGGATGCGCTGCTGGGAGAAATGCCCGTGCAGTTGCCGCCGCAGCTGCTGGCGCAGGCGCGCGAACGCCTGGA
GCGCCCCACGCCGCGGGTGGCGCTGGGGCAGGCATTGCGCGGCGTGGCCAGCAGCGCCATCGACGTGAGCGACGGGCTCG
TGGGCGACCTCGGCCACATCCTGCAGGCCTCGGGCGTGGGCGCGCGCATCAACACGTCGCTCGCCCCGCAGCTCATGGCG
GCCTGCGCCGGGCATGCCCCCGGGCAACTGCCCTGCGGCCGGGAAAACCTGCTGCGCTGCGTGCTGGCCGGGGGCGACGA
TTACGAACTGCTGTTCACAGCCCCCCCCGGCCGGCGCGCGCAGGTCGAGGCCGCGGCCCGCCAGGGGGGAACGCGCGCCA
CCTGCATCGGCGCCATCGAGGCCGAGCCCGGCCTGCGGCTGCTCGACGCGCAGGGCCAGCAAATGGACGCGCAATACCTG
GCCTTCGACCACTTCCGCTGA

Upstream 100 bases:

>100_bases
AAGCTTCCGCCCCCCGCCGCAGGGGCGCGCGCACGGACAGGAACATCCGGACAGGAAACCGAAGCCCGCGCCGCCCGGCG
GCTGCGCGTATGCTCGGCCC

Downstream 100 bases:

>100_bases
ACGCGCGCGGCAGAGGCGCTGCTAGCATTGCCCTCCCCCAGTCCTACCCAGAGAGAAGGAGCGCGGATGTCCTCTGCATG
CCCGGGCACGGCCCATTCCA

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MGEFDLIARYFRRPVRRAALGVGDDCALLAPAAGMQLAVSSDMLVEGRHFFADVYPAHLGHKALAVNLSDLAACGARPLA
FTLALALPRADEVWLQGFSEGLLALAGEHGCELVGGDTTQGPLNICITVFGEVPAGQALLRSGARPGDDLWVSGHLGDAR
LALDALLGEMPVQLPPQLLAQARERLERPTPRVALGQALRGVASSAIDVSDGLVGDLGHILQASGVGARINTSLAPQLMA
ACAGHAPGQLPCGRENLLRCVLAGGDDYELLFTAPPGRRAQVEAAARQGGTRATCIGAIEAEPGLRLLDAQGQQMDAQYL
AFDHFR

Sequences:

>Translated_326_residues
MGEFDLIARYFRRPVRRAALGVGDDCALLAPAAGMQLAVSSDMLVEGRHFFADVYPAHLGHKALAVNLSDLAACGARPLA
FTLALALPRADEVWLQGFSEGLLALAGEHGCELVGGDTTQGPLNICITVFGEVPAGQALLRSGARPGDDLWVSGHLGDAR
LALDALLGEMPVQLPPQLLAQARERLERPTPRVALGQALRGVASSAIDVSDGLVGDLGHILQASGVGARINTSLAPQLMA
ACAGHAPGQLPCGRENLLRCVLAGGDDYELLFTAPPGRRAQVEAAARQGGTRATCIGAIEAEPGLRLLDAQGQQMDAQYL
AFDHFR
>Mature_325_residues
GEFDLIARYFRRPVRRAALGVGDDCALLAPAAGMQLAVSSDMLVEGRHFFADVYPAHLGHKALAVNLSDLAACGARPLAF
TLALALPRADEVWLQGFSEGLLALAGEHGCELVGGDTTQGPLNICITVFGEVPAGQALLRSGARPGDDLWVSGHLGDARL
ALDALLGEMPVQLPPQLLAQARERLERPTPRVALGQALRGVASSAIDVSDGLVGDLGHILQASGVGARINTSLAPQLMAA
CAGHAPGQLPCGRENLLRCVLAGGDDYELLFTAPPGRRAQVEAAARQGGTRATCIGAIEAEPGLRLLDAQGQQMDAQYLA
FDHFR

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=328, Percent_Identity=46.0365853658537, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34099; Mature: 33967

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFDLIARYFRRPVRRAALGVGDDCALLAPAAGMQLAVSSDMLVEGRHFFADVYPAHLG
CCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEEECCCCEECCHHHHHHHHHHHCC
HKALAVNLSDLAACGARPLAFTLALALPRADEVWLQGFSEGLLALAGEHGCELVGGDTTQ
CEEEEEEHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
GPLNICITVFGEVPAGQALLRSGARPGDDLWVSGHLGDARLALDALLGEMPVQLPPQLLA
CCEEEEEEEECCCCCCHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHH
QARERLERPTPRVALGQALRGVASSAIDVSDGLVGDLGHILQASGVGARINTSLAPQLMA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
ACAGHAPGQLPCGRENLLRCVLAGGDDYELLFTAPPGRRAQVEAAARQGGTRATCIGAIE
HHCCCCCCCCCCCHHHHHEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEEE
AEPGLRLLDAQGQQMDAQYLAFDHFR
CCCCCEEECCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
GEFDLIARYFRRPVRRAALGVGDDCALLAPAAGMQLAVSSDMLVEGRHFFADVYPAHLG
CHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEEECCCCEECCHHHHHHHHHHHCC
HKALAVNLSDLAACGARPLAFTLALALPRADEVWLQGFSEGLLALAGEHGCELVGGDTTQ
CEEEEEEHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
GPLNICITVFGEVPAGQALLRSGARPGDDLWVSGHLGDARLALDALLGEMPVQLPPQLLA
CCEEEEEEEECCCCCCHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHH
QARERLERPTPRVALGQALRGVASSAIDVSDGLVGDLGHILQASGVGARINTSLAPQLMA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
ACAGHAPGQLPCGRENLLRCVLAGGDDYELLFTAPPGRRAQVEAAARQGGTRATCIGAIE
HHCCCCCCCCCCCHHHHHEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEEE
AEPGLRLLDAQGQQMDAQYLAFDHFR
CCCCCEEECCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]