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The map label for this gene is pgpA [H]

Identifier: 120609133

GI number: 120609133

Start: 464975

End: 465517

Strand: Reverse

Name: pgpA [H]

Synonym: Aave_0430

Alternate gene names: 120609133

Gene position: 465517-464975 (Counterclockwise)

Preceding gene: 120609134

Following gene: 120609132

Centisome position: 8.7

GC content: 72.01

Gene sequence:

>543_bases
ATGAACGCCTTGCCTCCCCAGCCCGCGGCCGGAGCGGCCGCGGCCCCCCGCAGGGCCAGCGCCGCCTTCATGCGGTCCCA
CCCGGCGCACTGGATCGCCCTGGGCTTCGGCGCAGGCCTCTCGCCGCGCGCGCCCGGCACCGTGGGTACGGCCTGGGCGT
GGCTGGCCTATCTGCTGCTGCAGCAGTGGCTGTCCCCCCTGCAGATCGGCGGGCTCATCCTGGCCGGCACGCTCGTGGGC
TGGTGGGCCTGCACCACCACCGCCCGCCACCTGCGCGTGGCCGACCCGGGATGCGTGGTGTGGGACGAGATCGTGGCGTT
CTGGTGCGTGCTCTGGCTGGCAATGCCCATGGGCTTCTGGGGCCAGTGCGCGGCGTTCGCGCTGTTCCGCTTTTTCGATG
CCGCCAAGCCCGGGCCCGTGGCCTGGGCGGACCAGCTGTTCAAAGGCTTCGGCTGGCGCGGCGGCTGGGGCATCCTCTTC
GACGACTTCGTGGCAGCGTTCTGCGCGCTGTTCGTGATTGCACTCTGGAGGGTGCTGTGGTGA

Upstream 100 bases:

>100_bases
TCGCCTGGCAGCAGCCCCTGGCGCCGGGCGCCGGGGCGCGCTTCACGGCGGAGCACGTGGTGCGCCACGGCAAGGACGTG
GAACTGAACGAGAACCGCCG

Downstream 100 bases:

>100_bases
GCGGCGACATCGCCCTCCTCGCACAGGCGCTCCCGGCCCGCGGCTGGATGCTGGCCACGGCCGAAAGCTGCACCGGCGGC
ATGATCGCCGGCGCATGCAC

Product: phosphatidylglycerophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNALPPQPAAGAAAAPRRASAAFMRSHPAHWIALGFGAGLSPRAPGTVGTAWAWLAYLLLQQWLSPLQIGGLILAGTLVG
WWACTTTARHLRVADPGCVVWDEIVAFWCVLWLAMPMGFWGQCAAFALFRFFDAAKPGPVAWADQLFKGFGWRGGWGILF
DDFVAAFCALFVIALWRVLW

Sequences:

>Translated_180_residues
MNALPPQPAAGAAAAPRRASAAFMRSHPAHWIALGFGAGLSPRAPGTVGTAWAWLAYLLLQQWLSPLQIGGLILAGTLVG
WWACTTTARHLRVADPGCVVWDEIVAFWCVLWLAMPMGFWGQCAAFALFRFFDAAKPGPVAWADQLFKGFGWRGGWGILF
DDFVAAFCALFVIALWRVLW
>Mature_180_residues
MNALPPQPAAGAAAAPRRASAAFMRSHPAHWIALGFGAGLSPRAPGTVGTAWAWLAYLLLQQWLSPLQIGGLILAGTLVG
WWACTTTARHLRVADPGCVVWDEIVAFWCVLWLAMPMGFWGQCAAFALFRFFDAAKPGPVAWADQLFKGFGWRGGWGILF
DDFVAAFCALFVIALWRVLW

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=159, Percent_Identity=38.3647798742138, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 19618; Mature: 19618

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPPQPAAGAAAAPRRASAAFMRSHPAHWIALGFGAGLSPRAPGTVGTAWAWLAYLLL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
QQWLSPLQIGGLILAGTLVGWWACTTTARHLRVADPGCVVWDEIVAFWCVLWLAMPMGFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCCH
GQCAAFALFRFFDAAKPGPVAWADQLFKGFGWRGGWGILFDDFVAAFCALFVIALWRVLW
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNALPPQPAAGAAAAPRRASAAFMRSHPAHWIALGFGAGLSPRAPGTVGTAWAWLAYLLL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
QQWLSPLQIGGLILAGTLVGWWACTTTARHLRVADPGCVVWDEIVAFWCVLWLAMPMGFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCCH
GQCAAFALFRFFDAAKPGPVAWADQLFKGFGWRGGWGILFDDFVAAFCALFVIALWRVLW
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]