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The map label for this gene is ychE [H]

Identifier: 120609022

GI number: 120609022

Start: 351782

End: 352417

Strand: Reverse

Name: ychE [H]

Synonym: Aave_0319

Alternate gene names: 120609022

Gene position: 352417-351782 (Counterclockwise)

Preceding gene: 120609023

Following gene: 120609021

Centisome position: 6.58

GC content: 66.98

Gene sequence:

>636_bases
ATGGACCTCAAACCCCTCATCACCCTGCTGGCCATCGTGAACCCGCTGGCCATCGTGCCCTTCTTCATCCACTACACCGA
CGGTTTCTCGCCGCGGCAGCGGCGGCGCACCATCCAGGTGGCGGCCTTCAGCGCGTTCTGCGTCATCGCGGCCTGCGCGC
TGCTGGGCCTGCAAATCCTGGAGTTCTTCAACATTTCGCTGCAGAGCTTCCAGGTGGGCGGCGGCATGCTGCTGCTCATC
AGCGCGATGAACATGCTCAACGCCCAGCCCGCGGAAGCGAAACCGCACACGCACGAACTGGAAGAAGGCGCCGAGAAGGC
CGCCCAGGGCGACAGCATCGCCGTGGTGCCGCTCACCATCCCGCTGCTCACCGGGCCCGCGAGCATGTCCACCGTGGTGA
TCTATGCCGACCGGGCGCAGACCGTCTGGCAGCATCTCGCTCTGGTGGGCTACGGTGTGGTGATCGCCCTGGCCACGGCG
GTGTGCTTCGCGCTCGCCGACCCGATCGCGCGCGTGCTGGGCAAGACCGGCATCAACGTGATGACGCGGCTCATGGGCCT
GATCCTGGCCGCGCTGGCCGTCGAGGTGATGGCCGATGGGCTGGGCAAGCTCTTTCCCGTCCTGGTGGCGCGCTGA

Upstream 100 bases:

>100_bases
GGCCGAATCCATCGTCTGGCTGCTGTCGGACGCCGCGAGCTACACCACCATGAGCCTGCTGGACGTTTCCGGCGGCCGCT
GAACCGGACACCGACATCCC

Downstream 100 bases:

>100_bases
CCATGGCCGCCCGCCTGCTGCTCGTGGAAGACGATCCGGCCATCGCGCGCACCGTGGCCTACGCCCTGGAACGCGATGGC
CTGGCGGTGAGCCACAGCCT

Product: multiple antibiotic resistance (MarC)-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MDLKPLITLLAIVNPLAIVPFFIHYTDGFSPRQRRRTIQVAAFSAFCVIAACALLGLQILEFFNISLQSFQVGGGMLLLI
SAMNMLNAQPAEAKPHTHELEEGAEKAAQGDSIAVVPLTIPLLTGPASMSTVVIYADRAQTVWQHLALVGYGVVIALATA
VCFALADPIARVLGKTGINVMTRLMGLILAALAVEVMADGLGKLFPVLVAR

Sequences:

>Translated_211_residues
MDLKPLITLLAIVNPLAIVPFFIHYTDGFSPRQRRRTIQVAAFSAFCVIAACALLGLQILEFFNISLQSFQVGGGMLLLI
SAMNMLNAQPAEAKPHTHELEEGAEKAAQGDSIAVVPLTIPLLTGPASMSTVVIYADRAQTVWQHLALVGYGVVIALATA
VCFALADPIARVLGKTGINVMTRLMGLILAALAVEVMADGLGKLFPVLVAR
>Mature_211_residues
MDLKPLITLLAIVNPLAIVPFFIHYTDGFSPRQRRRTIQVAAFSAFCVIAACALLGLQILEFFNISLQSFQVGGGMLLLI
SAMNMLNAQPAEAKPHTHELEEGAEKAAQGDSIAVVPLTIPLLTGPASMSTVVIYADRAQTVWQHLALVGYGVVIALATA
VCFALADPIARVLGKTGINVMTRLMGLILAALAVEVMADGLGKLFPVLVAR

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787494, Length=210, Percent_Identity=37.1428571428571, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789842, Length=198, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1787809, Length=204, Percent_Identity=26.9607843137255, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 22406; Mature: 22406

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKPLITLLAIVNPLAIVPFFIHYTDGFSPRQRRRTIQVAAFSAFCVIAACALLGLQIL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFFNISLQSFQVGGGMLLLISAMNMLNAQPAEAKPHTHELEEGAEKAAQGDSIAVVPLTI
HHHHHHHHHEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEE
PLLTGPASMSTVVIYADRAQTVWQHLALVGYGVVIALATAVCFALADPIARVLGKTGINV
EEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MTRLMGLILAALAVEVMADGLGKLFPVLVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLKPLITLLAIVNPLAIVPFFIHYTDGFSPRQRRRTIQVAAFSAFCVIAACALLGLQIL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFFNISLQSFQVGGGMLLLISAMNMLNAQPAEAKPHTHELEEGAEKAAQGDSIAVVPLTI
HHHHHHHHHEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEE
PLLTGPASMSTVVIYADRAQTVWQHLALVGYGVVIALATAVCFALADPIARVLGKTGINV
EEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MTRLMGLILAALAVEVMADGLGKLFPVLVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2015910; 9097039; 9278503 [H]