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The map label for this gene is creB [H]

Identifier: 120609021

GI number: 120609021

Start: 351096

End: 351779

Strand: Reverse

Name: creB [H]

Synonym: Aave_0318

Alternate gene names: 120609021

Gene position: 351779-351096 (Counterclockwise)

Preceding gene: 120609022

Following gene: 120609020

Centisome position: 6.57

GC content: 73.1

Gene sequence:

>684_bases
ATGGCCGCCCGCCTGCTGCTCGTGGAAGACGATCCGGCCATCGCGCGCACCGTGGCCTACGCCCTGGAACGCGATGGCCT
GGCGGTGAGCCACAGCCTGCTGCTGGGCGATGCCCGCGGCCTGCTGCGCGCCCACCGCTTCGACCTGCTGGTGCTGGACG
TGGGCCTGCCCGACGGCAGCGGCCTGGATCTGCTGCGCGAACTGCGCCAGCAGGGCAGCGCCCTGCCCGTGCTCATGCTC
AGCGCCCACGGAGAGGAGATCGACCGCGTGCTGGGCCTGGAACTCGGTGCCGACGACTACCTGCCCAAGCCCTTCAGCCC
GCGCGAACTGGCCGCCCGGGCCAAGGCCCTGCTGCGCCGTGCCGCCGCGCCTGCGGCGGCGCCCGCCTCCCCGGTCACCG
GCCCCTTCCATGACGACGCCGCCGGCCAGCGCATGCACCTGCACGGAAGACCGCTGGCGCTCACGCGCCGGGAATACCGC
CTGCTGTCCCAGCTGCTCGCGGGCGCGGGCCGCATCCACACGCGCGAGGCCCTGCTGGCCGGAGCCTGGGGCGGCGACAG
CGAGAGCACCGACCGCACCGTGGACACGCACATCAAGACCCTGCGCGCCAAGCTGCGCGAGGCCGACCCGTCGCGCGAGT
ACATCCATACCCACCGGGGCATGGGCTATTCACTAGAGGTATGA

Upstream 100 bases:

>100_bases
TGATGACGCGGCTCATGGGCCTGATCCTGGCCGCGCTGGCCGTCGAGGTGATGGCCGATGGGCTGGGCAAGCTCTTTCCC
GTCCTGGTGGCGCGCTGACC

Downstream 100 bases:

>100_bases
AGCCGCCCCTGACGCGCTTCGCGCCATCCCCCTTCCGCTGGCAAGGAGCTTGACCCATGCGCCTCGGGCTGCGGCTGCTT
TTCGCGTTCTTCCTCATCAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MAARLLLVEDDPAIARTVAYALERDGLAVSHSLLLGDARGLLRAHRFDLLVLDVGLPDGSGLDLLRELRQQGSALPVLML
SAHGEEIDRVLGLELGADDYLPKPFSPRELAARAKALLRRAAAPAAAPASPVTGPFHDDAAGQRMHLHGRPLALTRREYR
LLSQLLAGAGRIHTREALLAGAWGGDSESTDRTVDTHIKTLRAKLREADPSREYIHTHRGMGYSLEV

Sequences:

>Translated_227_residues
MAARLLLVEDDPAIARTVAYALERDGLAVSHSLLLGDARGLLRAHRFDLLVLDVGLPDGSGLDLLRELRQQGSALPVLML
SAHGEEIDRVLGLELGADDYLPKPFSPRELAARAKALLRRAAAPAAAPASPVTGPFHDDAAGQRMHLHGRPLALTRREYR
LLSQLLAGAGRIHTREALLAGAWGGDSESTDRTVDTHIKTLRAKLREADPSREYIHTHRGMGYSLEV
>Mature_226_residues
AARLLLVEDDPAIARTVAYALERDGLAVSHSLLLGDARGLLRAHRFDLLVLDVGLPDGSGLDLLRELRQQGSALPVLMLS
AHGEEIDRVLGLELGADDYLPKPFSPRELAARAKALLRRAAAPAAAPASPVTGPFHDDAAGQRMHLHGRPLALTRREYRL
LSQLLAGAGRIHTREALLAGAWGGDSESTDRTVDTHIKTLRAKLREADPSREYIHTHRGMGYSLEV

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=48.2456140350877, Blast_Score=193, Evalue=9e-51,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=38.7665198237885, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=39.2070484581498, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=36.7256637168142, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=40.7079646017699, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=37.3873873873874, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.2678571428571, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=36.4864864864865, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=38.5964912280702, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=31.7391304347826, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=31.25, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=36, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=29.0598290598291, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24614; Mature: 24482

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARLLLVEDDPAIARTVAYALERDGLAVSHSLLLGDARGLLRAHRFDLLVLDVGLPDGS
CCEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCC
GLDLLRELRQQGSALPVLMLSAHGEEIDRVLGLELGADDYLPKPFSPRELAARAKALLRR
CHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AAAPAAAPASPVTGPFHDDAAGQRMHLHGRPLALTRREYRLLSQLLAGAGRIHTREALLA
HCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHEE
GAWGGDSESTDRTVDTHIKTLRAKLREADPSREYIHTHRGMGYSLEV
ECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECC
>Mature Secondary Structure 
AARLLLVEDDPAIARTVAYALERDGLAVSHSLLLGDARGLLRAHRFDLLVLDVGLPDGS
CEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCC
GLDLLRELRQQGSALPVLMLSAHGEEIDRVLGLELGADDYLPKPFSPRELAARAKALLRR
CHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AAAPAAAPASPVTGPFHDDAAGQRMHLHGRPLALTRREYRLLSQLLAGAGRIHTREALLA
HCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHEE
GAWGGDSESTDRTVDTHIKTLRAKLREADPSREYIHTHRGMGYSLEV
ECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]