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The map label for this gene is aldH [H]

Identifier: 120608823

GI number: 120608823

Start: 125410

End: 126897

Strand: Reverse

Name: aldH [H]

Synonym: Aave_0115

Alternate gene names: 120608823

Gene position: 126897-125410 (Counterclockwise)

Preceding gene: 120608828

Following gene: 120608821

Centisome position: 2.37

GC content: 75.6

Gene sequence:

>1488_bases
ATGACCACGCCCGACACCCTGCAATCCATCGACGCGCGCACCGGCCAGCCCGGGGGCGACGCCTGGGACGCCTCCACGCC
GGCCGCCATCGACGCTGCCGTGGCCGCCGCTGCACAGGCGGCAGACGCTTTCGCCGCGCGCAGCGCCGCCGACCGCGCGG
GCCTGCTGCGCGCCCTGGCCGACGCCCTGGAATCGCAGCGCGAAACCCTGGTGCCCATCGCCGACCGCGAGACCGCCCTG
GGCCCGGCCCGCCTGAACGGGGAACTGGATCGCACCGCCTTCCAGCTGCGCGGCTTCGCCACCGAGCTGGAGCGGGGTGC
GGCGCACGCGGTGGTGGACGACCCCGCGGTGGCCGGCGCGCCACCGGCCGGCCGGCCGCACCTCACCCGCGTTCGCGTGC
CCGTGGGGCCCGTCGCCATGTTCTCGGCCAGCAATTTCCCGTTCGCGTTCTCGGTGCTGGGCGGGGACACCGCTTCGGCG
CTGGCGGCCGGCTGCCCGGTGGTCGTGAAGGCGCACCCGGCCCATCCGGAGCTGTCCCGCCGGACGGCACGCCTCGCCCG
GCAGGTCGTTGCGGCGCAGGGCCTGCCCGAAGGGGTCTTCCAGTTCGTGGAGGGCGGATCGGTGGCCACCGGCGTGCAAC
TGGTGCAGGCGCCGGCCATCGCCGCCGTGGCCTTCACCGGCTCGTTCAAGGGCGGCACCGCCCTGGCCCGGGTGGCGGCG
GAACGCCCCCGGCCCATTCCCTTCTACAGCGAGCTGGGCTCGGTGAATCCCCTGGTCGCCCTGCCTGCGGCGCTGCAGAC
CCGGGGCGCCGCGCTGGCGGAAACGCTGGCCGGCTCGATCTGCCTCGGCGCGGGCCAGTTCTGCACCAGCCCCGGCGTGA
TCGTGGTCCGCCGGGACGCCCCGGGCGACGCGTTCGTGCAGACGCTGGCGGACAAGCTCCAGGCGCTCGCGCCGCACGCC
ATGCTCTCGGCGGGCATCCGCGCGCACTTCGACCACGGGGTGAGCGCGTGGAAGGCCCACGGCAAGGTCAGGCCGCTGGT
GGACGGCACGGCCGCGCCAGGCGCCACGCCGCGCCCCTTCCTGGCCGAGGTGCAGGCGGTGGATTTCATCGCCGACGCCG
CGCTGCACGAGGAAGTCTTCGGATCCGCCGCCCTGGTGGTGCGCACGGGCTCGGCCCGGGAGACGATCGACGTGCTGCGC
GCCGTCGGCGGCTCCCTCACCGTCACGCTCTGGGGCGCGGACGACGATACGGAGGACAACCGCGCGCTGGTGCGCGCCGC
CACCCAGGTGGCGGGCCGCGTGCTCTTCGCCGGCGTGCCCACCGGGGTGGCCGTCACGGCCGCCCAGCACCATGGTGGCC
CCTACCCCGCCAGCACCGCGCCCTTTACCACGTCGGTGGGCTACGCGGCGATGGATCGCTTCCTGCGCCCCGTGGCGCTG
CAGGATGCCCCTGGGTGGCTGGCCGCTCGCAACGGCGTTCCCTGCTGA

Upstream 100 bases:

>100_bases
AGGATTTGCGCACCCGCTGTCCATCTCTTGAGACGGCCCCGGCCTTCCCGGAGCTGCCCGCCCGACCTTCCGCCCAGGCC
CTTTTGCCAGGAGACATTCC

Downstream 100 bases:

>100_bases
GGTGCCGGGTGGCGGCCGCCGCCGGCCTTCATGGTGCGCCCCGGCGCTGCCCCCCCTGCTTCGACCCGCCAGCCCCGGCG
CGGCTGCCGCCCGCTCCGGG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MTTPDTLQSIDARTGQPGGDAWDASTPAAIDAAVAAAAQAADAFAARSAADRAGLLRALADALESQRETLVPIADRETAL
GPARLNGELDRTAFQLRGFATELERGAAHAVVDDPAVAGAPPAGRPHLTRVRVPVGPVAMFSASNFPFAFSVLGGDTASA
LAAGCPVVVKAHPAHPELSRRTARLARQVVAAQGLPEGVFQFVEGGSVATGVQLVQAPAIAAVAFTGSFKGGTALARVAA
ERPRPIPFYSELGSVNPLVALPAALQTRGAALAETLAGSICLGAGQFCTSPGVIVVRRDAPGDAFVQTLADKLQALAPHA
MLSAGIRAHFDHGVSAWKAHGKVRPLVDGTAAPGATPRPFLAEVQAVDFIADAALHEEVFGSAALVVRTGSARETIDVLR
AVGGSLTVTLWGADDDTEDNRALVRAATQVAGRVLFAGVPTGVAVTAAQHHGGPYPASTAPFTTSVGYAAMDRFLRPVAL
QDAPGWLAARNGVPC

Sequences:

>Translated_495_residues
MTTPDTLQSIDARTGQPGGDAWDASTPAAIDAAVAAAAQAADAFAARSAADRAGLLRALADALESQRETLVPIADRETAL
GPARLNGELDRTAFQLRGFATELERGAAHAVVDDPAVAGAPPAGRPHLTRVRVPVGPVAMFSASNFPFAFSVLGGDTASA
LAAGCPVVVKAHPAHPELSRRTARLARQVVAAQGLPEGVFQFVEGGSVATGVQLVQAPAIAAVAFTGSFKGGTALARVAA
ERPRPIPFYSELGSVNPLVALPAALQTRGAALAETLAGSICLGAGQFCTSPGVIVVRRDAPGDAFVQTLADKLQALAPHA
MLSAGIRAHFDHGVSAWKAHGKVRPLVDGTAAPGATPRPFLAEVQAVDFIADAALHEEVFGSAALVVRTGSARETIDVLR
AVGGSLTVTLWGADDDTEDNRALVRAATQVAGRVLFAGVPTGVAVTAAQHHGGPYPASTAPFTTSVGYAAMDRFLRPVAL
QDAPGWLAARNGVPC
>Mature_494_residues
TTPDTLQSIDARTGQPGGDAWDASTPAAIDAAVAAAAQAADAFAARSAADRAGLLRALADALESQRETLVPIADRETALG
PARLNGELDRTAFQLRGFATELERGAAHAVVDDPAVAGAPPAGRPHLTRVRVPVGPVAMFSASNFPFAFSVLGGDTASAL
AAGCPVVVKAHPAHPELSRRTARLARQVVAAQGLPEGVFQFVEGGSVATGVQLVQAPAIAAVAFTGSFKGGTALARVAAE
RPRPIPFYSELGSVNPLVALPAALQTRGAALAETLAGSICLGAGQFCTSPGVIVVRRDAPGDAFVQTLADKLQALAPHAM
LSAGIRAHFDHGVSAWKAHGKVRPLVDGTAAPGATPRPFLAEVQAVDFIADAALHEEVFGSAALVVRTGSARETIDVLRA
VGGSLTVTLWGADDDTEDNRALVRAATQVAGRVLFAGVPTGVAVTAAQHHGGPYPASTAPFTTSVGYAAMDRFLRPVALQ
DAPGWLAARNGVPC

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=415, Percent_Identity=26.0240963855422, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4507229, Length=360, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI25952152, Length=389, Percent_Identity=24.4215938303342, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI25777721, Length=369, Percent_Identity=25.7452574525745, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI115387104, Length=301, Percent_Identity=24.9169435215947, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI21614513, Length=443, Percent_Identity=24.3792325056433, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI87081896, Length=420, Percent_Identity=28.8095238095238, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787250, Length=424, Percent_Identity=27.3584905660377, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789015, Length=348, Percent_Identity=26.7241379310345, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788042, Length=295, Percent_Identity=29.1525423728814, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786504, Length=264, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787558, Length=404, Percent_Identity=27.4752475247525, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87082295, Length=281, Percent_Identity=28.1138790035587, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25143876, Length=414, Percent_Identity=25.1207729468599, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25143874, Length=320, Percent_Identity=26.5625, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71995606, Length=326, Percent_Identity=30.3680981595092, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71995613, Length=327, Percent_Identity=30.5810397553517, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133930964, Length=311, Percent_Identity=26.0450160771704, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319478, Length=293, Percent_Identity=24.9146757679181, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=294, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362580, Length=296, Percent_Identity=28.0405405405405, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI62472918, Length=296, Percent_Identity=28.0405405405405, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI62472926, Length=296, Percent_Identity=28.0405405405405, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI62472936, Length=296, Percent_Identity=28.0405405405405, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356737, Length=296, Percent_Identity=28.0405405405405, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 50439; Mature: 50308

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPDTLQSIDARTGQPGGDAWDASTPAAIDAAVAAAAQAADAFAARSAADRAGLLRALA
CCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALESQRETLVPIADRETALGPARLNGELDRTAFQLRGFATELERGAAHAVVDDPAVAGA
HHHHHHHHCCCEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
PPAGRPHLTRVRVPVGPVAMFSASNFPFAFSVLGGDTASALAAGCPVVVKAHPAHPELSR
CCCCCCCCEEEECCCCCEEEEECCCCCEEEEEECCCHHHHHHCCCCEEEEECCCCCHHHH
RTARLARQVVAAQGLPEGVFQFVEGGSVATGVQLVQAPAIAAVAFTGSFKGGTALARVAA
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHH
ERPRPIPFYSELGSVNPLVALPAALQTRGAALAETLAGSICLGAGQFCTSPGVIVVRRDA
CCCCCCCHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
PGDAFVQTLADKLQALAPHAMLSAGIRAHFDHGVSAWKAHGKVRPLVDGTAAPGATPRPF
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCHH
LAEVQAVDFIADAALHEEVFGSAALVVRTGSARETIDVLRAVGGSLTVTLWGADDDTEDN
HHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCH
RALVRAATQVAGRVLFAGVPTGVAVTAAQHHGGPYPASTAPFTTSVGYAAMDRFLRPVAL
HHHHHHHHHHHCEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHC
QDAPGWLAARNGVPC
CCCCCCEECCCCCCC
>Mature Secondary Structure 
TTPDTLQSIDARTGQPGGDAWDASTPAAIDAAVAAAAQAADAFAARSAADRAGLLRALA
CCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALESQRETLVPIADRETALGPARLNGELDRTAFQLRGFATELERGAAHAVVDDPAVAGA
HHHHHHHHCCCEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
PPAGRPHLTRVRVPVGPVAMFSASNFPFAFSVLGGDTASALAAGCPVVVKAHPAHPELSR
CCCCCCCCEEEECCCCCEEEEECCCCCEEEEEECCCHHHHHHCCCCEEEEECCCCCHHHH
RTARLARQVVAAQGLPEGVFQFVEGGSVATGVQLVQAPAIAAVAFTGSFKGGTALARVAA
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHH
ERPRPIPFYSELGSVNPLVALPAALQTRGAALAETLAGSICLGAGQFCTSPGVIVVRRDA
CCCCCCCHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
PGDAFVQTLADKLQALAPHAMLSAGIRAHFDHGVSAWKAHGKVRPLVDGTAAPGATPRPF
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCHH
LAEVQAVDFIADAALHEEVFGSAALVVRTGSARETIDVLRAVGGSLTVTLWGADDDTEDN
HHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCH
RALVRAATQVAGRVLFAGVPTGVAVTAAQHHGGPYPASTAPFTTSVGYAAMDRFLRPVAL
HHHHHHHHHHHCEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHC
QDAPGWLAARNGVPC
CCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]