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The map label for this gene is rocF [H]

Identifier: 120608828

GI number: 120608828

Start: 132477

End: 133436

Strand: Reverse

Name: rocF [H]

Synonym: Aave_0120

Alternate gene names: 120608828

Gene position: 133436-132477 (Counterclockwise)

Preceding gene: 120608829

Following gene: 120608823

Centisome position: 2.49

GC content: 72.81

Gene sequence:

>960_bases
ATGGTCAACGCCCCCTTTCCACGCCCGGTCACGCTGATCGGCGTTCCCACCGACGTCGGCGCCGCCCGTCTGGGCGCGGC
CATGGGCCCGGACGCGCTGCGCGTGGCCCAGCTCGGTCCGGCGCTCGAACGGCTGGGACTGGAGGTCGAGGACCTGGGCA
ATCTGCACGGCCCGCCGAACCCGCGCGGCGAGCGCACGGCCGAGGGCCTGCGCAACCTCGCCGAATGCGAGGCATGGAAC
CGCTCCACGCACGATGCGGTGTTTGGCCAGTTGCAGGCCGGGCGCCTGCCGGTGATGCTGGGCGGCGACCACAACCTCGC
GATCGGCTCGATCAGCGCCGTGGCGCGCCACTGCCGGGAGACCGGCAAGCGGCTGCGCGTGCTCTGGCTGGACGCGCACT
CCGACAGCAACACGCCGGAGATCTCGCCCAGCGGCAACGTGCACGGCGTGCCGGTGGCCAGCCTCTGCGGGCTGGGTCCT
CCCGCGCTCGCGGCGCTCGGCGGCCCCGGGCCGGCGCTGCGTGGCGCGCAGATGTGCCAGATCGGGCTGCGCAGCGTGGA
TGCGGCCGAGAAGCGCATGATCCACGAGCTCGGGCTGGAGGTGTACGACATGCGCGCGATCGACGAACTCGGCATGCGCG
AGGTGATGCGCCGCGCGCTCGCCGGGCTGGAGGACGACGATGGCGCGCACCTGCACCTGAGCTTCGACGTGGACTTCCTC
GACCCGGAGATCGCGCCCGGCACGGGCACCACGGTGCGCGGCGGGCCGAACTACCGCGAGGCCCAGCTGTGCATGGAGAT
GATCGCGGACACGGGGCGCCTGGCCTCGCTCGACATCGTGGAGCTGAACCCCGCGCTCGACATCCGCAACCAGACCGCCG
AACTCGTGGTGGATCTGGTGGAGAGCCTGTTCGGCAAGAGCACGCTGGTGCGCGCGCCGGCCCCCGCCGGGCGGCGCTAA

Upstream 100 bases:

>100_bases
GCGCCGCGCGCTCCCACCTTCGCGCACGAGGCGGCCTGATCTCCGACGCCATCGCGCCGGTCCGCAACGCACAATGGCCG
CAGCAGGAGAAACGCCCACC

Downstream 100 bases:

>100_bases
CCCCGCAACTCAAGCCCCCGGGGCGCCGGCGACGGCAGCGGTGCGCGCCAGGTGCCGGCGCGCGAAATCCTCGTACCAGC
CAAGGCAGCCGGGATTGGCC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MVNAPFPRPVTLIGVPTDVGAARLGAAMGPDALRVAQLGPALERLGLEVEDLGNLHGPPNPRGERTAEGLRNLAECEAWN
RSTHDAVFGQLQAGRLPVMLGGDHNLAIGSISAVARHCRETGKRLRVLWLDAHSDSNTPEISPSGNVHGVPVASLCGLGP
PALAALGGPGPALRGAQMCQIGLRSVDAAEKRMIHELGLEVYDMRAIDELGMREVMRRALAGLEDDDGAHLHLSFDVDFL
DPEIAPGTGTTVRGGPNYREAQLCMEMIADTGRLASLDIVELNPALDIRNQTAELVVDLVESLFGKSTLVRAPAPAGRR

Sequences:

>Translated_319_residues
MVNAPFPRPVTLIGVPTDVGAARLGAAMGPDALRVAQLGPALERLGLEVEDLGNLHGPPNPRGERTAEGLRNLAECEAWN
RSTHDAVFGQLQAGRLPVMLGGDHNLAIGSISAVARHCRETGKRLRVLWLDAHSDSNTPEISPSGNVHGVPVASLCGLGP
PALAALGGPGPALRGAQMCQIGLRSVDAAEKRMIHELGLEVYDMRAIDELGMREVMRRALAGLEDDDGAHLHLSFDVDFL
DPEIAPGTGTTVRGGPNYREAQLCMEMIADTGRLASLDIVELNPALDIRNQTAELVVDLVESLFGKSTLVRAPAPAGRR
>Mature_319_residues
MVNAPFPRPVTLIGVPTDVGAARLGAAMGPDALRVAQLGPALERLGLEVEDLGNLHGPPNPRGERTAEGLRNLAECEAWN
RSTHDAVFGQLQAGRLPVMLGGDHNLAIGSISAVARHCRETGKRLRVLWLDAHSDSNTPEISPSGNVHGVPVASLCGLGP
PALAALGGPGPALRGAQMCQIGLRSVDAAEKRMIHELGLEVYDMRAIDELGMREVMRRALAGLEDDDGAHLHLSFDVDFL
DPEIAPGTGTTVRGGPNYREAQLCMEMIADTGRLASLDIVELNPALDIRNQTAELVVDLVESLFGKSTLVRAPAPAGRR

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=305, Percent_Identity=39.0163934426229, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI10947139, Length=282, Percent_Identity=37.5886524822695, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71996843, Length=208, Percent_Identity=35.0961538461538, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325146, Length=305, Percent_Identity=33.7704918032787, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24638886, Length=307, Percent_Identity=34.5276872964169, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 33780; Mature: 33780

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNAPFPRPVTLIGVPTDVGAARLGAAMGPDALRVAQLGPALERLGLEVEDLGNLHGPPN
CCCCCCCCCEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
PRGERTAEGLRNLAECEAWNRSTHDAVFGQLQAGRLPVMLGGDHNLAIGSISAVARHCRE
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHHHHHH
TGKRLRVLWLDAHSDSNTPEISPSGNVHGVPVASLCGLGPPALAALGGPGPALRGAQMCQ
HCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHCCCCCHHHHHHHHHH
IGLRSVDAAEKRMIHELGLEVYDMRAIDELGMREVMRRALAGLEDDDGAHLHLSFDVDFL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEC
DPEIAPGTGTTVRGGPNYREAQLCMEMIADTGRLASLDIVELNPALDIRNQTAELVVDLV
CCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
ESLFGKSTLVRAPAPAGRR
HHHHCCCEEEECCCCCCCC
>Mature Secondary Structure
MVNAPFPRPVTLIGVPTDVGAARLGAAMGPDALRVAQLGPALERLGLEVEDLGNLHGPPN
CCCCCCCCCEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
PRGERTAEGLRNLAECEAWNRSTHDAVFGQLQAGRLPVMLGGDHNLAIGSISAVARHCRE
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHHHHHH
TGKRLRVLWLDAHSDSNTPEISPSGNVHGVPVASLCGLGPPALAALGGPGPALRGAQMCQ
HCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHCCCCCHHHHHHHHHH
IGLRSVDAAEKRMIHELGLEVYDMRAIDELGMREVMRRALAGLEDDDGAHLHLSFDVDFL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEC
DPEIAPGTGTTVRGGPNYREAQLCMEMIADTGRLASLDIVELNPALDIRNQTAELVVDLV
CCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
ESLFGKSTLVRAPAPAGRR
HHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]