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The map label for this gene is visC [H]

Identifier: 120608821

GI number: 120608821

Start: 120827

End: 122143

Strand: Reverse

Name: visC [H]

Synonym: Aave_0113

Alternate gene names: 120608821

Gene position: 122143-120827 (Counterclockwise)

Preceding gene: 120608823

Following gene: 120608820

Centisome position: 2.28

GC content: 75.63

Gene sequence:

>1317_bases
ATGCCTGCCACTTCCTCCGTCCCGCCCGCCCCGCCCTCACCGGCCGTGGCTGCGCACCACTGCGACGTCCTGATCGTGGG
CGGCGGCCCCGCCGGCCTGTCGCTCGCAGTCTCGCTGGCGCAGGCCGGTTTCACGGCCACGGTGGTGGAGCGCCAGCCGG
ATGCCACCCTGGCCGAACCGGCGCCGGACGGCAGGGAAATCGCGCTCACCCACCCCAGCGCGGACACGCTGCGGCGCCTG
GGTTCCTGGCAGCGCCTGCTGCCGCACGAGATCGGGCGCATCCACGCAGCACATGTGCACGACGGCCCCGCGGGTGGCGG
GCAGCCGCTGCGCCTGCAGGCCGGGCGCGGCCCGGGCCACCTGGGCTGGATCGTTCCCAACCACGCCCTGCGGCGCACGG
CGCACGCCGCGGCCCTGGCCACGCCGGGCGTGCGGCTGCTGGCCGGCCGGCAGGTGGCGCACGTGGCCGTATCGGAGGAT
GCGGCGGAACTGCAATGCGCGTCCGCCAGCGGCGAACCGGATGGCGCCGCGCCCCTGCGGCTGCGCGCGCGCCTGCTGGT
GGCGGCGGACAGCCGCTTTTCCGCCACGCGGCGGCAGCTCGGTATCGGAGCGGCGAGCACCGATTTCGGGCGCACGGTCA
TCGTCTGCCGCATGCACCACGCGCTGGCGGGGGACGGCACCGCGCACGAATGCTTCGGCTATGCCCGCACCCTGGCCATC
CTGCCGCTGCCGCCCGACCCCGGCACGGGCGAGGCCCTGTGCTCGGTGGTGGTCACCACCCGCACCGACGACGCCACCGC
GCTGCTCGCTCTGCCTCCGGCCGATTTCGCCGCCCAGGTGCAGGCGCAGTTCGGCGACCGCCTCGGCGCGATGCGGCTGG
CCGGCGAGCGCCACGCCTATCCGCTGGTCGCCGTCTATGCCCGGCGCTTCAGCGGCCACCGCTGCGCCCTGCTGGGCGAT
GCGGCCGTGGGCATGCATCCGGTGACCGCGCATGGCTACAACCTGGGCCTCGCGGGCGTGGAGCGGCTGACCGCCGCCCT
GGTGCATGCGCGCGACACGGGCCGCGACATCGGTGACGCCGGCCTGCTGGAGCGGCACTACGCGCGGGCGCACCACCGGC
ATGCCTGGCCGCTGTACGAAGGCACGAATGCCATCGTGCGGCTCTATACCGACGACCGCCCGCTACCGCGCCTGCTGCGG
CGCGTGGTGCTGCAGGGTGCCCGCCGGCTCGCGCCGGTGCAGGCAGCGATCGTGGGACAGCTCATGGGAACGGCGCCCGA
GACCGGCGCCTGGGCGTCCGGCCCCGCAGGGCACTGA

Upstream 100 bases:

>100_bases
CAGGCCGAAAAAGCTGGAGAACTTGCGAAGCTTGATGCATGGCAATGGCAGACCCGCGCCACCGTGTCCACAATGGAGCG
TTCCACCGGCCATACCCGAG

Downstream 100 bases:

>100_bases
ACTTTCCCGCTTCGGCGGACTCTGCCATGCCGCCCTCGCACGGCATGCATTTTGTGTGTGCGGGGCGGCATGGCCCGGTC
TTCGTCACGAGGACCGGCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MPATSSVPPAPPSPAVAAHHCDVLIVGGGPAGLSLAVSLAQAGFTATVVERQPDATLAEPAPDGREIALTHPSADTLRRL
GSWQRLLPHEIGRIHAAHVHDGPAGGGQPLRLQAGRGPGHLGWIVPNHALRRTAHAAALATPGVRLLAGRQVAHVAVSED
AAELQCASASGEPDGAAPLRLRARLLVAADSRFSATRRQLGIGAASTDFGRTVIVCRMHHALAGDGTAHECFGYARTLAI
LPLPPDPGTGEALCSVVVTTRTDDATALLALPPADFAAQVQAQFGDRLGAMRLAGERHAYPLVAVYARRFSGHRCALLGD
AAVGMHPVTAHGYNLGLAGVERLTAALVHARDTGRDIGDAGLLERHYARAHHRHAWPLYEGTNAIVRLYTDDRPLPRLLR
RVVLQGARRLAPVQAAIVGQLMGTAPETGAWASGPAGH

Sequences:

>Translated_438_residues
MPATSSVPPAPPSPAVAAHHCDVLIVGGGPAGLSLAVSLAQAGFTATVVERQPDATLAEPAPDGREIALTHPSADTLRRL
GSWQRLLPHEIGRIHAAHVHDGPAGGGQPLRLQAGRGPGHLGWIVPNHALRRTAHAAALATPGVRLLAGRQVAHVAVSED
AAELQCASASGEPDGAAPLRLRARLLVAADSRFSATRRQLGIGAASTDFGRTVIVCRMHHALAGDGTAHECFGYARTLAI
LPLPPDPGTGEALCSVVVTTRTDDATALLALPPADFAAQVQAQFGDRLGAMRLAGERHAYPLVAVYARRFSGHRCALLGD
AAVGMHPVTAHGYNLGLAGVERLTAALVHARDTGRDIGDAGLLERHYARAHHRHAWPLYEGTNAIVRLYTDDRPLPRLLR
RVVLQGARRLAPVQAAIVGQLMGTAPETGAWASGPAGH
>Mature_437_residues
PATSSVPPAPPSPAVAAHHCDVLIVGGGPAGLSLAVSLAQAGFTATVVERQPDATLAEPAPDGREIALTHPSADTLRRLG
SWQRLLPHEIGRIHAAHVHDGPAGGGQPLRLQAGRGPGHLGWIVPNHALRRTAHAAALATPGVRLLAGRQVAHVAVSEDA
AELQCASASGEPDGAAPLRLRARLLVAADSRFSATRRQLGIGAASTDFGRTVIVCRMHHALAGDGTAHECFGYARTLAIL
PLPPDPGTGEALCSVVVTTRTDDATALLALPPADFAAQVQAQFGDRLGAMRLAGERHAYPLVAVYARRFSGHRCALLGDA
AVGMHPVTAHGYNLGLAGVERLTAALVHARDTGRDIGDAGLLERHYARAHHRHAWPLYEGTNAIVRLYTDDRPLPRLLRR
VVLQGARRLAPVQAAIVGQLMGTAPETGAWASGPAGH

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Escherichia coli, GI1789273, Length=404, Percent_Identity=31.1881188118812, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789274, Length=356, Percent_Identity=32.3033707865169, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786883, Length=400, Percent_Identity=28.25, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25146631, Length=453, Percent_Identity=22.9580573951435, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI19920760, Length=463, Percent_Identity=23.3261339092873, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 45665; Mature: 45533

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATSSVPPAPPSPAVAAHHCDVLIVGGGPAGLSLAVSLAQAGFTATVVERQPDATLAEP
CCCCCCCCCCCCCCCCEECCCCEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCC
APDGREIALTHPSADTLRRLGSWQRLLPHEIGRIHAAHVHDGPAGGGQPLRLQAGRGPGH
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEECCCCCCC
LGWIVPNHALRRTAHAAALATPGVRLLAGRQVAHVAVSEDAAELQCASASGEPDGAAPLR
EEEECCCHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCHHEEEECCCCCCCCCCCCE
LRARLLVAADSRFSATRRQLGIGAASTDFGRTVIVCRMHHALAGDGTAHECFGYARTLAI
EEEEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHCCCCCHHHHHHHEEEEEE
LPLPPDPGTGEALCSVVVTTRTDDATALLALPPADFAAQVQAQFGDRLGAMRLAGERHAY
EECCCCCCCHHHEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PLVAVYARRFSGHRCALLGDAAVGMHPVTAHGYNLGLAGVERLTAALVHARDTGRDIGDA
HHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCH
GLLERHYARAHHRHAWPLYEGTNAIVRLYTDDRPLPRLLRRVVLQGARRLAPVQAAIVGQ
HHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LMGTAPETGAWASGPAGH
HHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PATSSVPPAPPSPAVAAHHCDVLIVGGGPAGLSLAVSLAQAGFTATVVERQPDATLAEP
CCCCCCCCCCCCCCCEECCCCEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCC
APDGREIALTHPSADTLRRLGSWQRLLPHEIGRIHAAHVHDGPAGGGQPLRLQAGRGPGH
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEECCCCCCC
LGWIVPNHALRRTAHAAALATPGVRLLAGRQVAHVAVSEDAAELQCASASGEPDGAAPLR
EEEECCCHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCHHEEEECCCCCCCCCCCCE
LRARLLVAADSRFSATRRQLGIGAASTDFGRTVIVCRMHHALAGDGTAHECFGYARTLAI
EEEEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHCCCCCHHHHHHHEEEEEE
LPLPPDPGTGEALCSVVVTTRTDDATALLALPPADFAAQVQAQFGDRLGAMRLAGERHAY
EECCCCCCCHHHEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PLVAVYARRFSGHRCALLGDAAVGMHPVTAHGYNLGLAGVERLTAALVHARDTGRDIGDA
HHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCH
GLLERHYARAHHRHAWPLYEGTNAIVRLYTDDRPLPRLLRRVVLQGARRLAPVQAAIVGQ
HHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LMGTAPETGAWASGPAGH
HHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]