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The map label for this gene is yeaD [H]

Identifier: 120599238

GI number: 120599238

Start: 2811901

End: 2812749

Strand: Direct

Name: yeaD [H]

Synonym: Sputw3181_2434

Alternate gene names: 120599238

Gene position: 2811901-2812749 (Clockwise)

Preceding gene: 120599234

Following gene: 120599250

Centisome position: 59.72

GC content: 48.17

Gene sequence:

>849_bases
ATGGGTTCAGTCACTACTCAAAAGCACGCTAACGGGCTTGATTATGTCGAAGTGAATACGGCGTTATGTCAGGCAAGAAT
TTTTTTGCAGGGCGCGCAAATCGACTATTTTCAACCCGTAGGCAAACCACCTTTGCTGTGGGTTTCATCGGCTGACGATT
ATCAACCCGGTAATGGTCTCCGTGGCGGTGTCCCCGTATGCTGGCCTTGGTTTGGCATGAGTAGTGAAGCGAACTTTCCC
CAACACGGTTTCGCCCGAACCCGTATTTGGGCGCTGGAATCGGTAGAAATGCGTAATCAGTTAGTGGATTTACGTTTTAG
CTTAAAAATCAGTGAGCAAGATAAAATCTATTGGCCGCATAACACTGAGGTCAGCATGTTATTCACCCTAGGCGATACCC
TAAGCATTAGCCTTGTGAATACCAACTTAGACGATGAAACCGTCACGCTTACCCAAGCGCTGCACAGCTATTTCCCGATT
GAGGATATCCACCAACTCAAGGCCAGCGGTTTTAGTGGTTCAAAATACATCGAATTTGCCGAGGGGCCTTATCCGCAAAC
CACGGATGAAGTGCTGTTTGATCGCGAGACAGATCGTGTCTATACCGAACTCGGCCCTGTGCAGTTATTGCATACGCCGC
AGGGGATAATCGAAGTCAGCCGTGAAAACAGCCAATCAGCGGTATTATGGAATCCATGGATTGAAAAGTCACAACGCCTT
GGCCGATTTAATCCAGAGGATTATCTGACCATGGTCTGCCTAGAAGCGGCCAATGTGTTAGAAGATAAAGTCGTGCTCGC
GCCAGGAGAAACCCACAGTTTAGTGACCCACATTCGTTGGAAAGACTAA

Upstream 100 bases:

>100_bases
CCGTAAATTGATCGCAACAAAGCCTTATGTTATAGCGGAAAACTTTGTAAGCTAACTGCCTGTTTTTCTGATATGCAGCA
GAGTTAAGGATATTGTTACT

Downstream 100 bases:

>100_bases
CGATTTAATATCCAAGTTCTTAATATCCTAGTCAAAAACGATACAAACAAAAATGCCCAGTTCGATACTAATGCGGACTG
AGCATTTTTATAACAGACGA

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MGSVTTQKHANGLDYVEVNTALCQARIFLQGAQIDYFQPVGKPPLLWVSSADDYQPGNGLRGGVPVCWPWFGMSSEANFP
QHGFARTRIWALESVEMRNQLVDLRFSLKISEQDKIYWPHNTEVSMLFTLGDTLSISLVNTNLDDETVTLTQALHSYFPI
EDIHQLKASGFSGSKYIEFAEGPYPQTTDEVLFDRETDRVYTELGPVQLLHTPQGIIEVSRENSQSAVLWNPWIEKSQRL
GRFNPEDYLTMVCLEAANVLEDKVVLAPGETHSLVTHIRWKD

Sequences:

>Translated_282_residues
MGSVTTQKHANGLDYVEVNTALCQARIFLQGAQIDYFQPVGKPPLLWVSSADDYQPGNGLRGGVPVCWPWFGMSSEANFP
QHGFARTRIWALESVEMRNQLVDLRFSLKISEQDKIYWPHNTEVSMLFTLGDTLSISLVNTNLDDETVTLTQALHSYFPI
EDIHQLKASGFSGSKYIEFAEGPYPQTTDEVLFDRETDRVYTELGPVQLLHTPQGIIEVSRENSQSAVLWNPWIEKSQRL
GRFNPEDYLTMVCLEAANVLEDKVVLAPGETHSLVTHIRWKD
>Mature_281_residues
GSVTTQKHANGLDYVEVNTALCQARIFLQGAQIDYFQPVGKPPLLWVSSADDYQPGNGLRGGVPVCWPWFGMSSEANFPQ
HGFARTRIWALESVEMRNQLVDLRFSLKISEQDKIYWPHNTEVSMLFTLGDTLSISLVNTNLDDETVTLTQALHSYFPIE
DIHQLKASGFSGSKYIEFAEGPYPQTTDEVLFDRETDRVYTELGPVQLLHTPQGIIEVSRENSQSAVLWNPWIEKSQRLG
RFNPEDYLTMVCLEAANVLEDKVVLAPGETHSLVTHIRWKD

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=283, Percent_Identity=33.2155477031802, Blast_Score=141, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6323746, Length=241, Percent_Identity=31.9502074688797, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19921284, Length=268, Percent_Identity=27.6119402985075, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28574481, Length=135, Percent_Identity=27.4074074074074, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 31919; Mature: 31788

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVTTQKHANGLDYVEVNTALCQARIFLQGAQIDYFQPVGKPPLLWVSSADDYQPGNGL
CCCCCCCCCCCCCCEEEEHHHHHHEEEEEECCCEEEECCCCCCCEEEEECCCCCCCCCCC
RGGVPVCWPWFGMSSEANFPQHGFARTRIWALESVEMRNQLVDLRFSLKISEQDKIYWPH
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHEEEEEEEEEECCCCCEECCC
NTEVSMLFTLGDTLSISLVNTNLDDETVTLTQALHSYFPIEDIHQLKASGFSGSKYIEFA
CCCEEEEEEECCEEEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEC
EGPYPQTTDEVLFDRETDRVYTELGPVQLLHTPQGIIEVSRENSQSAVLWNPWIEKSQRL
CCCCCCCCHHHEECCCCCHHHHHCCCEEEEECCCCEEEEECCCCCCEEEECHHHHHHHHC
GRFNPEDYLTMVCLEAANVLEDKVVLAPGETHSLVTHIRWKD
CCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECC
>Mature Secondary Structure 
GSVTTQKHANGLDYVEVNTALCQARIFLQGAQIDYFQPVGKPPLLWVSSADDYQPGNGL
CCCCCCCCCCCCCEEEEHHHHHHEEEEEECCCEEEECCCCCCCEEEEECCCCCCCCCCC
RGGVPVCWPWFGMSSEANFPQHGFARTRIWALESVEMRNQLVDLRFSLKISEQDKIYWPH
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHEEEEEEEEEECCCCCEECCC
NTEVSMLFTLGDTLSISLVNTNLDDETVTLTQALHSYFPIEDIHQLKASGFSGSKYIEFA
CCCEEEEEEECCEEEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEC
EGPYPQTTDEVLFDRETDRVYTELGPVQLLHTPQGIIEVSRENSQSAVLWNPWIEKSQRL
CCCCCCCCHHHEECCCCCHHHHHCCCEEEEECCCCEEEEECCCCCCEEEECHHHHHHHHC
GRFNPEDYLTMVCLEAANVLEDKVVLAPGETHSLVTHIRWKD
CCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]