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The map label for this gene is asnC

Identifier: 120599027

GI number: 120599027

Start: 2569662

End: 2571062

Strand: Direct

Name: asnC

Synonym: Sputw3181_2222

Alternate gene names: 120599027

Gene position: 2569662-2571062 (Clockwise)

Preceding gene: 120599025

Following gene: 120599029

Centisome position: 54.58

GC content: 46.97

Gene sequence:

>1401_bases
ATGAGCATTGCATCTGTCGCTTCTGTATTTAAAGGTGAGCACGCGGTCGGTTCTAAAGTCACAGTACGTGGCTGGGTCAG
AACTCGTCGTGATTCTAAAGCCGGTATTTCTTTTTTAGCTGTCTATGACGGTTCCTGCTTTAATCCGATCCAAGGTGTCG
TGCCCAATAGCCTCGAAAATTACGACAACGAAGTGTTAAAGCTAACTGCAGGCTGCTCTGTCGTAATGACAGGCGACGTG
GTTGAATCTCCTGGCGCAGGCCAGGCATTTGAGCTACAAGTGACTGAACTTGAAGTCACTGGCTGGGTTGATGATCCAGA
CACATACCCAATGGCCGCTAAGCGTCATTCGATTGAGCATCTTCGTGAGCTCGCTCACCTGCGTCCACGCACTAACATTA
TTGGTGCTGTTGCCCGCGTTCGTAACTGTTTATCCCAAGCGATTCACCGTTTCTACCACGAAGAAGGCTTTATTTGGGTT
TCTACACCACTTATCACTGCATCAGATTGCGAAGGCGCGGGTGAAATGTTCCGCGTATCGACTTTAGATATGGAAAACCT
GCCCCGCACCAGTGAAGGCAAAGTCGATTACGATAAGGATTTCTTCGGTAAAGAGGCTTTCTTAACTGTATCAGGGCAAT
TAAACGGTGAAACTTACGCCTGTGCACTGTCAAAAATTTATACCTTTGGCCCAACATTCAGAGCAGAAAACTCCAATACT
AGCCGTCACTTAGCTGAGTTTTGGATGGTTGAACCCGAAGTTGCCTTCGCGACCTTAAGCGATATCGCAGGTCTTGCCGA
AGCGATGCTGAAATACGCCTTCAATGCCGTATTAACCGAGCGTATGGATGATTTACAATTCTTCGCACAGCACGTAGATA
AAACGGTTATCGAGCGTTTACAATCTTTTGTGTCGAGTGATTTTGCCCAAGTGGACTACACCGATGCGGTTGATATCCTG
CAAAAATGTGGCAAAACCTTTGAATTCCCAGTTTCTTGGGGTATTGACCTTTCTTCTGAGCACGAGCGTTATTTAGCCGA
AGAACATTTCAAAGCCCCAGTTGTGGTGAAGAACTATCCAAAGGACATTAAAGCCTTCTATATGCGCTTAAACGAAGACG
GCAAAACCGTTGCCGCAATGGACGTATTAGCACCCGGCATTGGTGAAATTATCGGGGGTTCTCAACGTGAAGAACGTTTA
GATGTGCTGGATATGCGTTTAGCCGAAATGGATCTGAACAAAGAAGATTACTGGTGGTATCGTGACCTTCGCCGTTATGG
CACAGTGCCACACGCGGGCTTTGGTTTAGGTTTTGAGCGTTTAGTGTCTTATGTGACTGGCGTCTCTAACATCCGTGATG
TGATCCCCTTCCCACGTGCACCACGTACAGCAAACTTCTAA

Upstream 100 bases:

>100_bases
ACCTCAGGATACCTTTTTCAGCTTGAGAAAAGCCACCAGCAAGGTAATATAAACCTCCAAAATTTTCATATAAAACGTTT
CGTTGGAGAACTAAGCAACA

Downstream 100 bases:

>100_bases
TTCACTTTGATATTACTGGTGAATACTAAAACGCGCTTCGGCGCGTTTTTTATTGCGTTTGAAGTCATCCTAATCACCTG
AAAACCTGAAAACCTGATGA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLENYDNEVLKLTAGCSVVMTGDV
VESPGAGQAFELQVTELEVTGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWV
STPLITASDCEGAGEMFRVSTLDMENLPRTSEGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFATLSDIAGLAEAMLKYAFNAVLTERMDDLQFFAQHVDKTVIERLQSFVSSDFAQVDYTDAVDIL
QKCGKTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDMRLAEMDLNKEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF

Sequences:

>Translated_466_residues
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLENYDNEVLKLTAGCSVVMTGDV
VESPGAGQAFELQVTELEVTGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWV
STPLITASDCEGAGEMFRVSTLDMENLPRTSEGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFATLSDIAGLAEAMLKYAFNAVLTERMDDLQFFAQHVDKTVIERLQSFVSSDFAQVDYTDAVDIL
QKCGKTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDMRLAEMDLNKEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF
>Mature_465_residues
SIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLENYDNEVLKLTAGCSVVMTGDVV
ESPGAGQAFELQVTELEVTGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVS
TPLITASDCEGAGEMFRVSTLDMENLPRTSEGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFATLSDIAGLAEAMLKYAFNAVLTERMDDLQFFAQHVDKTVIERLQSFVSSDFAQVDYTDAVDILQ
KCGKTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLD
VLDMRLAEMDLNKEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=41.5948275862069, Blast_Score=374, Evalue=1e-104,
Organism=Homo sapiens, GI4758762, Length=455, Percent_Identity=28.3516483516484, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI45439306, Length=356, Percent_Identity=27.8089887640449, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=80.2575107296137, Blast_Score=808, Evalue=0.0,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=33.9449541284404, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17556372, Length=429, Percent_Identity=30.5361305361305, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71984122, Length=452, Percent_Identity=29.4247787610619, Blast_Score=188, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=345, Percent_Identity=27.8260869565217, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319872, Length=487, Percent_Identity=35.7289527720739, Blast_Score=290, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6321807, Length=464, Percent_Identity=30.1724137931034, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=482, Percent_Identity=24.2738589211618, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=35.5603448275862, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI19921528, Length=479, Percent_Identity=28.6012526096033, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=27.1137026239067, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52181; Mature: 52050

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLEN
CCHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCHHHH
YDNEVLKLTAGCSVVMTGDVVESPGAGQAFELQVTELEVTGWVDDPDTYPMAAKRHSIEH
HCCCEEEEECCCEEEEECCEECCCCCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVSTPLITASDCEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTSEGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFATLSDIAGLAEAMLKYAFNAVLTERMDDLQFFAQHVDKTVIERL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFVSSDFAQVDYTDAVDILQKCGKTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLAEMDLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLEN
CHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCHHHH
YDNEVLKLTAGCSVVMTGDVVESPGAGQAFELQVTELEVTGWVDDPDTYPMAAKRHSIEH
HCCCEEEEECCCEEEEECCEECCCCCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVSTPLITASDCEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTSEGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFATLSDIAGLAEAMLKYAFNAVLTERMDDLQFFAQHVDKTVIERL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFVSSDFAQVDYTDAVDILQKCGKTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLAEMDLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA