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The map label for this gene is nudL [H]

Identifier: 120599025

GI number: 120599025

Start: 2568571

End: 2569155

Strand: Direct

Name: nudL [H]

Synonym: Sputw3181_2220

Alternate gene names: 120599025

Gene position: 2568571-2569155 (Clockwise)

Preceding gene: 120599024

Following gene: 120599027

Centisome position: 54.55

GC content: 44.44

Gene sequence:

>585_bases
ATGGATCAAGCTGAATTTAGATTGAGATTTAATCTACATCCTTTAGCTCGGCAAGATCCGGCTGCTTTCCCTCACCTTGG
ATTACGCAAAGCGGCGGTATTGCTCCCTGTTCAAGACATTGCAGGTGAACTGAGTTTGATCTTAACCCAAAGACCTATGC
ATCTGCGTGCCCACCCAGGGCAAATTAGTTTTCCTGGCGGTAAAATTGAACCAAGTGATACGAATGCAATTGCTGCTGCA
CTAAGAGAAGCCGAAGAGGAAATCGGCCTGTTACGGCACAATGTGGATGTTGTAGGCACTTTTCCTGCTCACAATACCTT
TACTGGATTTGAAATCACCCCAGTGATAGGTATCGTCAAGCAAGCATTTGTGATGAAACTCGATCCCGGTGAAGTTGCCG
ATTGTTTCTCTGTACCGTTAAGTTTTTTTATTGAACCAACCCATCGTCACCAGAAACGTTTTTTACGTCAAGGCCGTTAT
TACAATGTGCATTTTATCCCCTACCAACAGCGATTTATATGGGGAGCAACGGCAGCAATCATTGATCATCTCTGCCGCCA
TTTAAGTATCCCTTCGCAAATTTAG

Upstream 100 bases:

>100_bases
CGAATATCAAGAAACCTTTGATAAAATCAGCCGTATTTTACCTTTGCTTGGCGCTGAATGAAAAAACCTTAATTTTGATA
CTGGATAAACGAGAACTTCG

Downstream 100 bases:

>100_bases
CCCCGCTAAATAACAAAAAGTTAAATGACAAAGCGAATATATAAGCCAGCGACAATCGAGGTGAGCAGTAATAGCGGAAT
GTTGAACCAATAGCCTAATT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MDQAEFRLRFNLHPLARQDPAAFPHLGLRKAAVLLPVQDIAGELSLILTQRPMHLRAHPGQISFPGGKIEPSDTNAIAAA
LREAEEEIGLLRHNVDVVGTFPAHNTFTGFEITPVIGIVKQAFVMKLDPGEVADCFSVPLSFFIEPTHRHQKRFLRQGRY
YNVHFIPYQQRFIWGATAAIIDHLCRHLSIPSQI

Sequences:

>Translated_194_residues
MDQAEFRLRFNLHPLARQDPAAFPHLGLRKAAVLLPVQDIAGELSLILTQRPMHLRAHPGQISFPGGKIEPSDTNAIAAA
LREAEEEIGLLRHNVDVVGTFPAHNTFTGFEITPVIGIVKQAFVMKLDPGEVADCFSVPLSFFIEPTHRHQKRFLRQGRY
YNVHFIPYQQRFIWGATAAIIDHLCRHLSIPSQI
>Mature_194_residues
MDQAEFRLRFNLHPLARQDPAAFPHLGLRKAAVLLPVQDIAGELSLILTQRPMHLRAHPGQISFPGGKIEPSDTNAIAAA
LREAEEEIGLLRHNVDVVGTFPAHNTFTGFEITPVIGIVKQAFVMKLDPGEVADCFSVPLSFFIEPTHRHQKRFLRQGRY
YNVHFIPYQQRFIWGATAAIIDHLCRHLSIPSQI

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=168, Percent_Identity=37.5, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1788115, Length=165, Percent_Identity=39.3939393939394, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17510677, Length=159, Percent_Identity=34.5911949685535, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536993, Length=118, Percent_Identity=33.0508474576271, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323180, Length=224, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859683, Length=168, Percent_Identity=37.5, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 21844; Mature: 21844

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQAEFRLRFNLHPLARQDPAAFPHLGLRKAAVLLPVQDIAGELSLILTQRPMHLRAHPG
CCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHEEEEHHHHHCCEEEEEECCCCEEECCCC
QISFPGGKIEPSDTNAIAAALREAEEEIGLLRHNVDVVGTFPAHNTFTGFEITPVIGIVK
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHH
QAFVMKLDPGEVADCFSVPLSFFIEPTHRHQKRFLRQGRYYNVHFIPYQQRFIWGATAAI
HHHEEECCCCCHHHHHHCCHHEEECCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHH
IDHLCRHLSIPSQI
HHHHHHHCCCCCCC
>Mature Secondary Structure
MDQAEFRLRFNLHPLARQDPAAFPHLGLRKAAVLLPVQDIAGELSLILTQRPMHLRAHPG
CCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHEEEEHHHHHCCEEEEEECCCCEEECCCC
QISFPGGKIEPSDTNAIAAALREAEEEIGLLRHNVDVVGTFPAHNTFTGFEITPVIGIVK
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHH
QAFVMKLDPGEVADCFSVPLSFFIEPTHRHQKRFLRQGRYYNVHFIPYQQRFIWGATAAI
HHHEEECCCCCHHHHHHCCHHEEECCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHH
IDHLCRHLSIPSQI
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]