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The map label for this gene is pabB [H]

Identifier: 120599024

GI number: 120599024

Start: 2567131

End: 2568531

Strand: Direct

Name: pabB [H]

Synonym: Sputw3181_2219

Alternate gene names: 120599024

Gene position: 2567131-2568531 (Clockwise)

Preceding gene: 120599019

Following gene: 120599025

Centisome position: 54.52

GC content: 46.97

Gene sequence:

>1401_bases
ATGGCAATTAGGGCGTCAATACAGCTTGCATCACGCCAACTTGACTGGACATTAAGCACCACAGAAGTATTCGAATACTT
TGCTAAAGACGAGTGGGCAATTCTGCTCGATTCTGCTAACGCGCCGCATCAAGATGCTAAATTCGATATTATTTGCGCGG
CGCCTATTGCCACTTTAGTCACCAAAGGTGAGCGAAGTGAAATAACCCTTATGCAATCAGATCTGACGTTGCCGGCAAAG
ACCAACGTAACAGATGATCCATTTGAACTCGTTAACTCATTATTAAATCATTGGTATCCAAACGCCCTTGAAAGTGGCTT
CCCTTTTGCAGGAGGCGCCATGGGTAGCTTTAGTTACGATTTAGGGCGTCGAATCGAAACGCTGCCAATGACTGCCAAGC
AGGATATTCAACTGCCAGAAATGAATATCGGCTTTTACGACTGGGCGCTTATCTTCAATTACCAAACCCAGTGTTGGCAT
TTGTTGCACTATTTAGGCGAGAAAGCCCTCGAGATTGAGTTGAATAAAATTCAACATAAACTCACTAAAAAGCCAAACTC
AGCGGCCTTTATGCTCACTAGCCCATGGGCAACACAGATAAATAAAGCCCAATACACGAGAAAATTTGAAGCTGTACAAG
CCTATTTACACAGCGGTGATTGCTATCAAATAAATTTAACCCAACGATTTGAGGCAAGTTACCAAGGTGATGAATGGGCG
GCGTACTGCCAATTACGTAAGGCCAATAAAGCCCCCTTCTCGGCCTTTATGCGTCTACCGCAAAACGCTATTTTGTCGAT
TTCCCCCGAGCGTTTTATCCAGCTTCGCGGTGATGATATTCAAACCAAACCCATCAAAGGTACGATGCCACGTCATGCTG
ATCCACTGCTTGATACCAAGGCCGCCAGCACGCTTGCAAGCTCGCCAAAGGATCGTGCTGAGAATGTGATGATTGTCGAT
TTGCTGCGCAACGACATTGGCAAAGTGGCCGCAGCCGGTTCAGTACGTGTACCCCATCTCTTTGAGATTGAGAGTTTTCC
CGCTGTGCATCACTTAGTCAGTACCGTTACCGCCAAACTCGCTAGCCAATTCACGGCGAGTGATTTACTGCGCGCCGCAT
TCCCAGGCGGCTCGATTACCGGCGCACCCAAAATTCGCGCCATGGAAATTATCGAGGAGCTAGAACCGTCACGCAGAAGT
TTATACTGTGGTTGTATGGGATATTTAAGCCAAGATGGACAAATGGATACCAGCATCACCATTCGCACACTGATTGCCGA
ACGGGGTAAACTCTATTGCTGGGCGGGCGGTGGCATAGTGGCGGATTCAGAAGTGAATGCCGAATATCAAGAAACCTTTG
ATAAAATCAGCCGTATTTTACCTTTGCTTGGCGCTGAATGA

Upstream 100 bases:

>100_bases
CCTATGTGGCCTTACTTGTTTTTGTTTAATTCTTTCTGGGCCAATATGATACTCTTTCACATCTTTTTGGGCTACATCAC
ATTTTAGATAGGATTAATCG

Downstream 100 bases:

>100_bases
AAAAACCTTAATTTTGATACTGGATAAACGAGAACTTCGATGGATCAAGCTGAATTTAGATTGAGATTTAATCTACATCC
TTTAGCTCGGCAAGATCCGG

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MAIRASIQLASRQLDWTLSTTEVFEYFAKDEWAILLDSANAPHQDAKFDIICAAPIATLVTKGERSEITLMQSDLTLPAK
TNVTDDPFELVNSLLNHWYPNALESGFPFAGGAMGSFSYDLGRRIETLPMTAKQDIQLPEMNIGFYDWALIFNYQTQCWH
LLHYLGEKALEIELNKIQHKLTKKPNSAAFMLTSPWATQINKAQYTRKFEAVQAYLHSGDCYQINLTQRFEASYQGDEWA
AYCQLRKANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTMPRHADPLLDTKAASTLASSPKDRAENVMIVD
LLRNDIGKVAAAGSVRVPHLFEIESFPAVHHLVSTVTAKLASQFTASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRS
LYCGCMGYLSQDGQMDTSITIRTLIAERGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAE

Sequences:

>Translated_466_residues
MAIRASIQLASRQLDWTLSTTEVFEYFAKDEWAILLDSANAPHQDAKFDIICAAPIATLVTKGERSEITLMQSDLTLPAK
TNVTDDPFELVNSLLNHWYPNALESGFPFAGGAMGSFSYDLGRRIETLPMTAKQDIQLPEMNIGFYDWALIFNYQTQCWH
LLHYLGEKALEIELNKIQHKLTKKPNSAAFMLTSPWATQINKAQYTRKFEAVQAYLHSGDCYQINLTQRFEASYQGDEWA
AYCQLRKANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTMPRHADPLLDTKAASTLASSPKDRAENVMIVD
LLRNDIGKVAAAGSVRVPHLFEIESFPAVHHLVSTVTAKLASQFTASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRS
LYCGCMGYLSQDGQMDTSITIRTLIAERGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAE
>Mature_465_residues
AIRASIQLASRQLDWTLSTTEVFEYFAKDEWAILLDSANAPHQDAKFDIICAAPIATLVTKGERSEITLMQSDLTLPAKT
NVTDDPFELVNSLLNHWYPNALESGFPFAGGAMGSFSYDLGRRIETLPMTAKQDIQLPEMNIGFYDWALIFNYQTQCWHL
LHYLGEKALEIELNKIQHKLTKKPNSAAFMLTSPWATQINKAQYTRKFEAVQAYLHSGDCYQINLTQRFEASYQGDEWAA
YCQLRKANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTMPRHADPLLDTKAASTLASSPKDRAENVMIVDL
LRNDIGKVAAAGSVRVPHLFEIESFPAVHHLVSTVTAKLASQFTASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSL
YCGCMGYLSQDGQMDTSITIRTLIAERGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=442, Percent_Identity=56.3348416289593, Blast_Score=490, Evalue=1e-140,
Organism=Escherichia coli, GI1787518, Length=391, Percent_Identity=28.6445012787724, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1786809, Length=201, Percent_Identity=28.8557213930348, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87082077, Length=224, Percent_Identity=25.8928571428571, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=443, Percent_Identity=30.4740406320542, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324361, Length=400, Percent_Identity=26.5, Blast_Score=153, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 51944; Mature: 51813

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRASIQLASRQLDWTLSTTEVFEYFAKDEWAILLDSANAPHQDAKFDIICAAPIATLV
CCEEEEEHHHHCCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHH
TKGERSEITLMQSDLTLPAKTNVTDDPFELVNSLLNHWYPNALESGFPFAGGAMGSFSYD
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHH
LGRRIETLPMTAKQDIQLPEMNIGFYDWALIFNYQTQCWHLLHYLGEKALEIELNKIQHK
HHCCEEECCCCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHCCCEEEEHHHHHHHH
LTKKPNSAAFMLTSPWATQINKAQYTRKFEAVQAYLHSGDCYQINLTQRFEASYQGDEWA
HHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCHHH
AYCQLRKANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTMPRHADPLLDTK
HHHHHHHCCCCHHHHHHHCCCCCEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHH
AASTLASSPKDRAENVMIVDLLRNDIGKVAAAGSVRVPHLFEIESFPAVHHLVSTVTAKL
HHHHHHCCCHHHHCCEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
ASQFTASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSLYCGCMGYLSQDGQMDTSIT
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHEEHHHHHHHCCCCCCCCHHH
IRTLIAERGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAE
HHHHHHHCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIRASIQLASRQLDWTLSTTEVFEYFAKDEWAILLDSANAPHQDAKFDIICAAPIATLV
CEEEEEHHHHCCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHH
TKGERSEITLMQSDLTLPAKTNVTDDPFELVNSLLNHWYPNALESGFPFAGGAMGSFSYD
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHH
LGRRIETLPMTAKQDIQLPEMNIGFYDWALIFNYQTQCWHLLHYLGEKALEIELNKIQHK
HHCCEEECCCCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHCCCEEEEHHHHHHHH
LTKKPNSAAFMLTSPWATQINKAQYTRKFEAVQAYLHSGDCYQINLTQRFEASYQGDEWA
HHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCHHH
AYCQLRKANKAPFSAFMRLPQNAILSISPERFIQLRGDDIQTKPIKGTMPRHADPLLDTK
HHHHHHHCCCCHHHHHHHCCCCCEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHH
AASTLASSPKDRAENVMIVDLLRNDIGKVAAAGSVRVPHLFEIESFPAVHHLVSTVTAKL
HHHHHHCCCHHHHCCEEEHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
ASQFTASDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSLYCGCMGYLSQDGQMDTSIT
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHEEHHHHHHHCCCCCCCCHHH
IRTLIAERGKLYCWAGGGIVADSEVNAEYQETFDKISRILPLLGAE
HHHHHHHCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]