BacMap

Definition	Shewanella sp. W3-18-1 chromosome, complete genome.
Accession	NC_008750
Length	4,708,380

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The map label for this gene is fadH [H]

Identifier: 120598790

GI number: 120598790

Start: 2289969

End: 2290790

Strand: Direct

Name: fadH [H]

Synonym: Sputw3181_1976

Alternate gene names: 120598790

Gene position: 2289969-2290790 (Clockwise)

Preceding gene: 120598789

Following gene: 120598791

Centisome position: 48.64

GC content: 46.35

Gene sequence:

>822_bases
ATGTTTAATGCTACGATGTTTAACTATCAAGGTAAGAATGTTGTCGTTGTCGGAGGAACCAGTGGAATAAATCTCGCGAT
TGCCATTGCGTTCGCACAAGCTGGTGCCAATGTGGCCGTCGCGAGCCGCAGCCAAGATAAAATCGATGCCGCAGTATTGC
AGCTACAGCAAGTCAATCCAGAGGGGATTCATTTAGGAGTGAGTTTTGATGTGCGCGATCTTAGCGCCCTTGAAATTGGT
TTTGATAAAATCGCTTCTGAATTTGGTTTTATCGATGTGCTTGTCAGCGGCGCGGCGGGTAATTTTCCTGCAACAGCGGC
TAAGCTTTCAGCTAATGGCTTTAAGTCGGTGATGGACATCGATTTGCTGGGCAGTTTTCAAGTGCTAAAACAGGCTTATC
CTTTGCTACGTCGTCCTAATGGCAATATTATTCAAATCTCTGCGCCACAGGCTTTTATTGCAATGCCAATGCAAGTACAT
GTTTGTGCAGCAAAAGCTGGCGTGGATATGTTAACGCGAACCTTAGCTATTGAGTGGGGTTGTGAAGATTTACGAATAAA
CTCTATCGTACCAGGTCCGATTGCTGAGACCGAAGGTTTTAATCGTCTTGCACCGAGTGCTGCATTGCAGCAAAGCGTTG
CTCAATCTGTACCCTTAAAGCGTAATGGCACGGGACAGGATATTGCTAATGCGGCCTTATTTTTAGGCTCTGAATTAGCC
TCCTATATCACAGGCGTTGTTCTGCCAGTTGATGGTGGTTGGTCACTCGGTGGAGCGAGTATTGCGATGACAGAGTTGAG
TGAACGGGCTGCAAAAATGTAG

Upstream 100 bases:

>100_bases
CGTCGATCCATTAGCGGCCTTGCAAGCGATTTATCAATCATTGGCATAGAATAATAAATCACACCTGAGTGTTTATTCTC
ACTGTTCACGGAGAACGCCC

Downstream 100 bases:

>100_bases
TTTGGTGTTAGATTCTAGATATTCAAAATCGAGAACGTTGATTTTATATAGATTAAGTAGGTAATGATCCATGGCTAACG
CATTACAAGAGCAGCTACTG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MFNATMFNYQGKNVVVVGGTSGINLAIAIAFAQAGANVAVASRSQDKIDAAVLQLQQVNPEGIHLGVSFDVRDLSALEIG
FDKIASEFGFIDVLVSGAAGNFPATAAKLSANGFKSVMDIDLLGSFQVLKQAYPLLRRPNGNIIQISAPQAFIAMPMQVH
VCAAKAGVDMLTRTLAIEWGCEDLRINSIVPGPIAETEGFNRLAPSAALQQSVAQSVPLKRNGTGQDIANAALFLGSELA
SYITGVVLPVDGGWSLGGASIAMTELSERAAKM

Sequences:

>Translated_273_residues
MFNATMFNYQGKNVVVVGGTSGINLAIAIAFAQAGANVAVASRSQDKIDAAVLQLQQVNPEGIHLGVSFDVRDLSALEIG
FDKIASEFGFIDVLVSGAAGNFPATAAKLSANGFKSVMDIDLLGSFQVLKQAYPLLRRPNGNIIQISAPQAFIAMPMQVH
VCAAKAGVDMLTRTLAIEWGCEDLRINSIVPGPIAETEGFNRLAPSAALQQSVAQSVPLKRNGTGQDIANAALFLGSELA
SYITGVVLPVDGGWSLGGASIAMTELSERAAKM
>Mature_273_residues
MFNATMFNYQGKNVVVVGGTSGINLAIAIAFAQAGANVAVASRSQDKIDAAVLQLQQVNPEGIHLGVSFDVRDLSALEIG
FDKIASEFGFIDVLVSGAAGNFPATAAKLSANGFKSVMDIDLLGSFQVLKQAYPLLRRPNGNIIQISAPQAFIAMPMQVH
VCAAKAGVDMLTRTLAIEWGCEDLRINSIVPGPIAETEGFNRLAPSAALQQSVAQSVPLKRNGTGQDIANAALFLGSELA
SYITGVVLPVDGGWSLGGASIAMTELSERAAKM

Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=43.1451612903226, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=32.5396825396825, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI4503301, Length=248, Percent_Identity=31.8548387096774, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.9317269076305, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=31.9148936170213, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=31.1475409836066, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=27.710843373494, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=29.1497975708502, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=29.1497975708502, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=28.6274509803922, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=25.2688172043011, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=30.7392996108949, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=29.8804780876494, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=26.4, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=27.4900398406374, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082100, Length=264, Percent_Identity=27.6515151515151, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=26.5625, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=27.0916334661355, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=28.0632411067194, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.5193798449612, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=27.3092369477912, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787545, Length=266, Percent_Identity=27.8195488721804, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=32.9317269076305, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=31.7460317460317, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=32.4786324786325, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=27.3408239700375, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=30.8823529411765, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=29.8507462686567, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=27.9850746268657, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=29.1044776119403, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=30.4, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=28.7313432835821, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=27.3062730627306, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=28.8888888888889, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=28.0632411067194, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=31.3492063492063, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=28.0898876404494, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=27.4436090225564, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=283, Percent_Identity=25.4416961130742, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=27.5471698113208, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=25.4901960784314, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=25.6704980842912, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=26.8939393939394, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.515625, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=25.3787878787879, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=28.2051282051282, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=27.6119402985075, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=25.4826254826255, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=39.6825396825397, Blast_Score=172, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6322861, Length=212, Percent_Identity=27.3584905660377, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=31.1023622047244, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=29.4820717131474, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=29.0196078431373, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=30.952380952381, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=28.8617886178862, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=27.1317829457364, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=25.609756097561, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859837, Length=220, Percent_Identity=29.5454545454545, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 28493; Mature: 28493

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNATMFNYQGKNVVVVGGTSGINLAIAIAFAQAGANVAVASRSQDKIDAAVLQLQQVNP
CCCCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCC
EGIHLGVSFDVRDLSALEIGFDKIASEFGFIDVLVSGAAGNFPATAAKLSANGFKSVMDI
CCEEEEEEECCCCCHHHHHCHHHHHHHCCEEEEEEECCCCCCCCHHHHHCCCCCHHHHHH
DLLGSFQVLKQAYPLLRRPNGNIIQISAPQAFIAMPMQVHVCAAKAGVDMLTRTLAIEWG
HHCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCEEEEEEHHHHHHHHHHHHHHEEEC
CEDLRINSIVPGPIAETEGFNRLAPSAALQQSVAQSVPLKRNGTGQDIANAALFLGSELA
CCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
SYITGVVLPVDGGWSLGGASIAMTELSERAAKM
HHHCEEEEECCCCCCCCCCEEHHHHHHHHHHCC
>Mature Secondary Structure
MFNATMFNYQGKNVVVVGGTSGINLAIAIAFAQAGANVAVASRSQDKIDAAVLQLQQVNP
CCCCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCC
EGIHLGVSFDVRDLSALEIGFDKIASEFGFIDVLVSGAAGNFPATAAKLSANGFKSVMDI
CCEEEEEEECCCCCHHHHHCHHHHHHHCCEEEEEEECCCCCCCCHHHHHCCCCCHHHHHH
DLLGSFQVLKQAYPLLRRPNGNIIQISAPQAFIAMPMQVHVCAAKAGVDMLTRTLAIEWG
HHCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCEEEEEEHHHHHHHHHHHHHHEEEC
CEDLRINSIVPGPIAETEGFNRLAPSAALQQSVAQSVPLKRNGTGQDIANAALFLGSELA
CCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
SYITGVVLPVDGGWSLGGASIAMTELSERAAKM
HHHCEEEEECCCCCCCCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]