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The map label for this gene is rfbC [H]

Identifier: 120598288

GI number: 120598288

Start: 1657079

End: 1657627

Strand: Direct

Name: rfbC [H]

Synonym: Sputw3181_1466

Alternate gene names: 120598288

Gene position: 1657079-1657627 (Clockwise)

Preceding gene: 120598287

Following gene: 120598289

Centisome position: 35.19

GC content: 44.63

Gene sequence:

>549_bases
ATGAAAATTATCGATACCAAAATCCCCGACGTTAAGATCATCGAGCCTAGAGTCTTTGGCGATGATCGCGGTTTCTTTTT
TGAAAGCTTTAACCAACAGCAATTTGAAGCTGCTATCGGCTACCCAGTCAATTTTGTCCAAGACAATCACTCCAAATCGA
GCAAAGGGGTATTACGTGGTCTGCATTATCAACTTGCGCCCCATGTCCAAAGCAAGCTGGTGCGTTGCGTGGTTGGTGAA
GTTTTTGACGTGGCGGTGGATATTCGCCAAAGCTCACCTACATTTGGCCAATGGGTGGGGGTGCATCTTTCTGCAGAAAA
TAAGCGTCAACTGTGGATCCCTGAAGGGTTTGCCCACGGCTTTGTTACCTTGAGAGAAACAGCGGAGTTTTTGTATAAGA
CGACCAATTACTATTGCGCAGCCAGCGATAGAGGTATTCAGTGGAATGATGAAAAACTGGCGGTAGCATGGCCAATTGAA
GGTTTGATATTGACCTTATCTGATAAAGACAAACGACAGCCCATTTTTGAAAAGGCTGAATATTTGTAA

Upstream 100 bases:

>100_bases
TGTGTGAGTGGCTTGTTGGGAATGATTACGCGATAACTATTATCTCACCATTCACCATTCACCATTCACCATTCATTATT
AACAACACACGAATTAAAAC

Downstream 100 bases:

>100_bases
TGTCGGATTTGGCTACTAAAACCAAAAAAGGTCTCCAATGGAGCGCCATCGAGCGTCTTTTAACCCAAGGTATGCAGTTA
GGGATAACTCTGCTACTGGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKIIDTKIPDVKIIEPRVFGDDRGFFFESFNQQQFEAAIGYPVNFVQDNHSKSSKGVLRGLHYQLAPHVQSKLVRCVVGE
VFDVAVDIRQSSPTFGQWVGVHLSAENKRQLWIPEGFAHGFVTLRETAEFLYKTTNYYCAASDRGIQWNDEKLAVAWPIE
GLILTLSDKDKRQPIFEKAEYL

Sequences:

>Translated_182_residues
MKIIDTKIPDVKIIEPRVFGDDRGFFFESFNQQQFEAAIGYPVNFVQDNHSKSSKGVLRGLHYQLAPHVQSKLVRCVVGE
VFDVAVDIRQSSPTFGQWVGVHLSAENKRQLWIPEGFAHGFVTLRETAEFLYKTTNYYCAASDRGIQWNDEKLAVAWPIE
GLILTLSDKDKRQPIFEKAEYL
>Mature_182_residues
MKIIDTKIPDVKIIEPRVFGDDRGFFFESFNQQQFEAAIGYPVNFVQDNHSKSSKGVLRGLHYQLAPHVQSKLVRCVVGE
VFDVAVDIRQSSPTFGQWVGVHLSAENKRQLWIPEGFAHGFVTLRETAEFLYKTTNYYCAASDRGIQWNDEKLAVAWPIE
GLILTLSDKDKRQPIFEKAEYL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=173, Percent_Identity=67.0520231213873, Blast_Score=237, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17550412, Length=172, Percent_Identity=48.2558139534884, Blast_Score=156, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20840; Mature: 20840

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIDTKIPDVKIIEPRVFGDDRGFFFESFNQQQFEAAIGYPVNFVQDNHSKSSKGVLRG
CCCCCCCCCCEEEECCEEECCCCCCHHHCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHH
LHYQLAPHVQSKLVRCVVGEVFDVAVDIRQSSPTFGQWVGVHLSAENKRQLWIPEGFAHG
HHHHHCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEEECCCCEEEECCCCCCCC
FVTLRETAEFLYKTTNYYCAASDRGIQWNDEKLAVAWPIEGLILTLSDKDKRQPIFEKAE
EEEHHHHHHHHHHCCCEEEEECCCCCEECCCEEEEEECCCEEEEEECCCCCCCCHHHHHC
YL
CC
>Mature Secondary Structure
MKIIDTKIPDVKIIEPRVFGDDRGFFFESFNQQQFEAAIGYPVNFVQDNHSKSSKGVLRG
CCCCCCCCCCEEEECCEEECCCCCCHHHCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHH
LHYQLAPHVQSKLVRCVVGEVFDVAVDIRQSSPTFGQWVGVHLSAENKRQLWIPEGFAHG
HHHHHCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEEECCCCEEEECCCCCCCC
FVTLRETAEFLYKTTNYYCAASDRGIQWNDEKLAVAWPIEGLILTLSDKDKRQPIFEKAE
EEEHHHHHHHHHHCCCEEEEECCCCCEECCCEEEEEECCCEEEEEECCCCCCCCHHHHHC
YL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8170390; 8157605; 12384590; 12704152 [H]