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The map label for this gene is aaeR [H]

Identifier: 120598053

GI number: 120598053

Start: 1391942

End: 1392883

Strand: Direct

Name: aaeR [H]

Synonym: Sputw3181_1230

Alternate gene names: 120598053

Gene position: 1391942-1392883 (Clockwise)

Preceding gene: 120598047

Following gene: 120598055

Centisome position: 29.56

GC content: 51.7

Gene sequence:

>942_bases
ATGGACAGACTCGAAGCGGCTAAGGTGTTTGTGACTATTGTTGAGCGCGGCAGCATGATCAGCGCCGCTAATGCTTTAGA
CATGTCACGCTCTATGGTGACCCGTTATTTGAGCGAAATGGAAGACTGGTCTGGTGCTAGGTTGTTGCATCGCTCGACGC
GTAGCCTCAGTTTAACGCCTGCGGGTGAGCAAGTGCTGGATTATTGCCATCGACTGCTCGAACTGGCTAACGAAGTACCG
GCGGTCAGTCATGCTGGTGTGACGATCCCGCGGGGATTGCTTCGCATTAGCTGCTCACAATTTATGGCACATCAGATTTT
AGCGCCTGTAGTGCGCCAATATTTAGCCAGTTATCCGCAGGCGAGCGTGAATTTCCACGTGAGCAGCCAAACCGTCGATC
TGGTTGCTGAGCGAATTGATTTGGCTATTCGTATCACTAATGAGCTTGACCCTAATCTTATCGCGAGGCGCTTGGGTGAA
TGTGAGTCTGTGGTGTGCGCCGCACCGAGTTATCTTGCCGCGCGCGCCGCCGTGCTGCATCCCGAAGATTTAACTCAGCA
TAACTGCTTAACCTATTCCTATTTTGGCGATGTGATGTGGCGCTTTTATCAAACCGATGTAGGGGCGAAACAGGCTCAGG
CGCTGAACCCCGAGTCTAAGTTAAACCAAGGGCAGGCGTTTAATGTGCCAGTGAATGGTAATTTTAGCGCCAATGATTCC
ATGGTGGTGCTTAATGCCACGCTGGCGGGCGAGGGGATTGCGATGCAACCGCTATGGGCGGCGAAACCCTATTTAGATTC
GGGCCAGTTAGTGCCTTTATTAACTGAGTTCATGCCTCAATCCCTCGGTGTGTATGGCGTGTATCAATCCCGCAAACATA
TGCAGCCCGCCTTAAGAGTGATGATGGATATGCTGGTGGCCTACTTTGCCAGCTTGAATTGA

Upstream 100 bases:

>100_bases
TTAAAATGCCCATGTTTGTTGCATCAATCGGACGAATTACCGTGCGTTCTTGAGTCTATAAATGAGTCTTTGAGTGATTG
AAAGTGAGTGGAGATAGGTA

Downstream 100 bases:

>100_bases
AATAGTGCCAGTTTGAAATAGTGCCAGTTTGAAATAGCGAAAAATTCACGCCCTAAATTGAATGGAATAAAAAGGAGCTT
AACCTTTTTGAGTTAAACTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEDWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHAGVTIPRGLLRISCSQFMAHQILAPVVRQYLASYPQASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVLHPEDLTQHNCLTYSYFGDVMWRFYQTDVGAKQAQALNPESKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLN

Sequences:

>Translated_313_residues
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEDWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHAGVTIPRGLLRISCSQFMAHQILAPVVRQYLASYPQASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVLHPEDLTQHNCLTYSYFGDVMWRFYQTDVGAKQAQALNPESKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLN
>Mature_313_residues
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEDWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHAGVTIPRGLLRISCSQFMAHQILAPVVRQYLASYPQASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVLHPEDLTQHNCLTYSYFGDVMWRFYQTDVGAKQAQALNPESKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLN

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=313, Percent_Identity=33.5463258785943, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789440, Length=306, Percent_Identity=30.0653594771242, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI87081978, Length=312, Percent_Identity=29.8076923076923, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787589, Length=308, Percent_Identity=26.2987012987013, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786401, Length=306, Percent_Identity=27.4509803921569, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693193, Length=307, Percent_Identity=26.3843648208469, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787128, Length=305, Percent_Identity=24.5901639344262, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789173, Length=273, Percent_Identity=26.3736263736264, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786448, Length=295, Percent_Identity=24.7457627118644, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34569; Mature: 34569

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEDWSGARLLHRSTRSLSLTP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECCC
AGEQVLDYCHRLLELANEVPAVSHAGVTIPRGLLRISCSQFMAHQILAPVVRQYLASYPQ
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGECESVVCAAPSYLAARAAVLH
CCEEEEECHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHCC
PEDLTQHNCLTYSYFGDVMWRFYQTDVGAKQAQALNPESKLNQGQAFNVPVNGNFSANDS
CHHCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCCEEECCCCCCCCCCCC
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRV
EEEEEEEECCCCCEECCHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHH
MMDMLVAYFASLN
HHHHHHHHHHCCC
>Mature Secondary Structure
MDRLEAAKVFVTIVERGSMISAANALDMSRSMVTRYLSEMEDWSGARLLHRSTRSLSLTP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECCC
AGEQVLDYCHRLLELANEVPAVSHAGVTIPRGLLRISCSQFMAHQILAPVVRQYLASYPQ
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGECESVVCAAPSYLAARAAVLH
CCEEEEECHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHCC
PEDLTQHNCLTYSYFGDVMWRFYQTDVGAKQAQALNPESKLNQGQAFNVPVNGNFSANDS
CHHCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCCEEECCCCCCCCCCCC
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRV
EEEEEEEECCCCCEECCHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHH
MMDMLVAYFASLN
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]