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The map label for this gene is ydhC [C]

Identifier: 120598047

GI number: 120598047

Start: 1383658

End: 1384827

Strand: Direct

Name: ydhC [C]

Synonym: Sputw3181_1224

Alternate gene names: 120598047

Gene position: 1383658-1384827 (Clockwise)

Preceding gene: 120598044

Following gene: 120598053

Centisome position: 29.39

GC content: 47.01

Gene sequence:

>1170_bases
ATGAATATAAAACCCCCTTTAGGGCTCGCTGTGCTGCTAATGATATTTCCGCAAGCTATGGAAACCATCTATAGCCCAGC
ATTGCCGAATATTGCAGAAAACTTTGCCGTGTCGGTTGCTGGCGCATCGCAAACCTTATCTGTGTACTTTATTGCCTTTG
CCATAGGCGTATTTTGCTGGGGCCGCTTAGCCGACATTATTGGTCGTCGCAAAGCTATGCTCGCGGGATTAGTATGTTAT
GCCATTGGCTCAGCGTTAGCCTTGATGGTGAGCGATTTTAGCCTGTTGTTGCTGGCCCGCGTATTGTCGGCCTTTGGCGC
GGCAGTGGGTTCTGTGATTACCCAAACTATGATGCGTGACAGTTATAGTGGAGAAGAATTAGCCAAAGTCTTTTCTGTGA
TGGGAATGTCACTTGGAATTAGCCCTGTTATCGGATTGCTACTGGGCAGCGTTCTCAGTGCGTATTGGGGGTATCAAGGT
GTGTTTGTCGCACTTATGGTTTCTGCCATAGTGCTGTTGTTTTTGTCGGTAAAATCCTTACCTGAAACCAAACCCGCACA
TAGCCAGAAAATAGCGATAGGTGAGTTAGCGTTTAAGATGCTTACCGACAGCGGGATTATTAAGAACACCTTCTTGGTGG
CAGCGTTTAATCTGATGTGGTTTAGCTACTTTTCACTGGCACCATTTATGTTTGAGGCGCAAGGATTATCGACGCTTGCC
TTCGGAACTAGTGGCTTACTATTAGGCTTTGGCGCATTCCTTGGCAGTTATTTTAATAGAATATTGCTAGGTCGAGGCCA
CACCAGCGTCTGGCTGGTTCGCTTAGCCAGTGCAATCGCACTTGTCGGTGGATTGGGTATTTGGCTATTTCAATCAACTG
TAATAGGACTGAATAGTGTTTACTTTTTAGCGCCTATGCTCTTGATTGTGATTGCTTATGGGATCGCGATTCCAAACATA
CTCAGCTCGGCTCTGGCAAACTACCGTGCTTATACGGGCTCTGCTGGCGCACTCTTTGGACTGTTTTATTATATTTTGCT
CGGAGCGGGATTGGGCTTTGTGGGCATGATTAACCATCTCGGAGGCGTCATTACGTTGGCGGCATTGCTCTGTACTGGGC
TCTGTATTCGCGTCAGTACCGAGCAGGTTATTAACTCATCTCAGGCATAA

Upstream 100 bases:

>100_bases
GTCATGTTTGGATTTTATCTATACTGCGTCCTCTTTGACAAGTATGGAGTGACATTTCGGTAAACCAACTCATTTTGTTT
ACTAAAATTCAATTGAAATC

Downstream 100 bases:

>100_bases
ATCAAAAAGCCAAGGTATTTGTACCTTGGCTTTTTATCATCTGAGCTGACGTTTTGTTTCTCTTAGTTTTCGATCACAGT
TTTGTTATCAAGCTTTTGCC

Product: Bcr/CflA subfamily drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNIKPPLGLAVLLMIFPQAMETIYSPALPNIAENFAVSVAGASQTLSVYFIAFAIGVFCWGRLADIIGRRKAMLAGLVCY
AIGSALALMVSDFSLLLLARVLSAFGAAVGSVITQTMMRDSYSGEELAKVFSVMGMSLGISPVIGLLLGSVLSAYWGYQG
VFVALMVSAIVLLFLSVKSLPETKPAHSQKIAIGELAFKMLTDSGIIKNTFLVAAFNLMWFSYFSLAPFMFEAQGLSTLA
FGTSGLLLGFGAFLGSYFNRILLGRGHTSVWLVRLASAIALVGGLGIWLFQSTVIGLNSVYFLAPMLLIVIAYGIAIPNI
LSSALANYRAYTGSAGALFGLFYYILLGAGLGFVGMINHLGGVITLAALLCTGLCIRVSTEQVINSSQA

Sequences:

>Translated_389_residues
MNIKPPLGLAVLLMIFPQAMETIYSPALPNIAENFAVSVAGASQTLSVYFIAFAIGVFCWGRLADIIGRRKAMLAGLVCY
AIGSALALMVSDFSLLLLARVLSAFGAAVGSVITQTMMRDSYSGEELAKVFSVMGMSLGISPVIGLLLGSVLSAYWGYQG
VFVALMVSAIVLLFLSVKSLPETKPAHSQKIAIGELAFKMLTDSGIIKNTFLVAAFNLMWFSYFSLAPFMFEAQGLSTLA
FGTSGLLLGFGAFLGSYFNRILLGRGHTSVWLVRLASAIALVGGLGIWLFQSTVIGLNSVYFLAPMLLIVIAYGIAIPNI
LSSALANYRAYTGSAGALFGLFYYILLGAGLGFVGMINHLGGVITLAALLCTGLCIRVSTEQVINSSQA
>Mature_389_residues
MNIKPPLGLAVLLMIFPQAMETIYSPALPNIAENFAVSVAGASQTLSVYFIAFAIGVFCWGRLADIIGRRKAMLAGLVCY
AIGSALALMVSDFSLLLLARVLSAFGAAVGSVITQTMMRDSYSGEELAKVFSVMGMSLGISPVIGLLLGSVLSAYWGYQG
VFVALMVSAIVLLFLSVKSLPETKPAHSQKIAIGELAFKMLTDSGIIKNTFLVAAFNLMWFSYFSLAPFMFEAQGLSTLA
FGTSGLLLGFGAFLGSYFNRILLGRGHTSVWLVRLASAIALVGGLGIWLFQSTVIGLNSVYFLAPMLLIVIAYGIAIPNI
LSSALANYRAYTGSAGALFGLFYYILLGAGLGFVGMINHLGGVITLAALLCTGLCIRVSTEQVINSSQA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=322, Percent_Identity=27.9503105590062, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87082312, Length=333, Percent_Identity=24.6246246246246, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788509, Length=241, Percent_Identity=26.5560165975104, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790146, Length=175, Percent_Identity=29.1428571428571, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41126; Mature: 41126

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCHHHEECHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHCCHHHEECHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA