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The map label for this gene is qorA [H]

Identifier: 120597520

GI number: 120597520

Start: 768438

End: 769439

Strand: Direct

Name: qorA [H]

Synonym: Sputw3181_0689

Alternate gene names: 120597520

Gene position: 768438-769439 (Clockwise)

Preceding gene: 120597519

Following gene: 120597521

Centisome position: 16.32

GC content: 48.8

Gene sequence:

>1002_bases
ATGTCAGCTTTACCTAATGATTATGTCCATATCCATATTGAACAAGCTGGTGCACCTGAGGTGATGCAGCTCGCTCGCTC
CCCTTTACCTATCCCTTCGGCAGGACAAGTGCTTATTCGTGTGCATGCTGCAGGGGTGAATGGGCCTGATATCAAGCAAA
GAGTCGGTATATATCCGCCTCCGCCAGGGGCATCGCCCATTATAGGGCTTGAGGTTGCAGGGGAGATTTGCGCTCTGGGT
GACGGCGTAAACCAATGGCAAATCGGCGATAAGGTATGCGCCTTAGTTCCGGGCGGTGGTTATGGTGAGTATGCGCTGAC
CTATGCTGCCCATTGTTTACCAATACCAACTGATTTTAGTTATGTTCAGGCTGCTGCATTACCGGAAACCTTGTTCACCG
TATGGGGCAATTTGTTTATGCGTGCGGGGCTAAAAGCAGGTGAAACTGTGCTCATCCATGGCGGTTCTGGCGGTATCGGT
AGCACAGCCATTCAGCTTGCAAGTGCGTTAGGAGCCAAAGTGATTGCTACCACAGGCAAGGATGAAAAGCGCGACTACTG
CTTGGGTCTAGGTGCCCATGAGGTGATTAACTATCAAAGCCAAAACTTTGTTGAAGCCGTGATGGCATTCACGCAAGACA
AAGGAGTAAATGTGGTATTTGATATTGCGGGTGGTGACTTTATCAACTTGAATTTACAAGCTCTTGCAATGGATGGGCGA
ATGGTGTCAGTAGCCATGCAGCGTGGCCCTAAAGCCGAGGTTGAACTCTTTCGCTTAATGGCAAAGCGCATCGTTTGGAC
AGGTTCCACCTTAAGACCGCAGAGTGTGGAGTCTAAAGCCGCAATCGCCAATGAATTGCAAACAACCGTATGGCCGCTTT
TGGATAGTCATAAAATAGTGCCTAATATTTTTGCAACTTTTCCGTTGAATGAGGCTCCTAAAGCGCATGCTTTGATGGAG
TCTGGCGAGCATAGGGGAAAAGTGGTTCTCACATTGGTTTGA

Upstream 100 bases:

>100_bases
TGCCGTTTTCACGCGGTAATTGACGAGTTTTGTGCAATGTCTTAGTTAACTATTCGCATATAAAAGAGTTAAGCCGTTAC
CTTCGCTAAAGGAATATTCT

Downstream 100 bases:

>100_bases
TTAAAACGGCAAGTGAGCGATTAGGATGAATTTTACAGTAAAGCTGTCCTAGTCAGTCTTTTGATGGATTAAAGGGCTGA
ATAAAAACTGGCAGCGATGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSALPNDYVHIHIEQAGAPEVMQLARSPLPIPSAGQVLIRVHAAGVNGPDIKQRVGIYPPPPGASPIIGLEVAGEICALG
DGVNQWQIGDKVCALVPGGGYGEYALTYAAHCLPIPTDFSYVQAAALPETLFTVWGNLFMRAGLKAGETVLIHGGSGGIG
STAIQLASALGAKVIATTGKDEKRDYCLGLGAHEVINYQSQNFVEAVMAFTQDKGVNVVFDIAGGDFINLNLQALAMDGR
MVSVAMQRGPKAEVELFRLMAKRIVWTGSTLRPQSVESKAAIANELQTTVWPLLDSHKIVPNIFATFPLNEAPKAHALME
SGEHRGKVVLTLV

Sequences:

>Translated_333_residues
MSALPNDYVHIHIEQAGAPEVMQLARSPLPIPSAGQVLIRVHAAGVNGPDIKQRVGIYPPPPGASPIIGLEVAGEICALG
DGVNQWQIGDKVCALVPGGGYGEYALTYAAHCLPIPTDFSYVQAAALPETLFTVWGNLFMRAGLKAGETVLIHGGSGGIG
STAIQLASALGAKVIATTGKDEKRDYCLGLGAHEVINYQSQNFVEAVMAFTQDKGVNVVFDIAGGDFINLNLQALAMDGR
MVSVAMQRGPKAEVELFRLMAKRIVWTGSTLRPQSVESKAAIANELQTTVWPLLDSHKIVPNIFATFPLNEAPKAHALME
SGEHRGKVVLTLV
>Mature_332_residues
SALPNDYVHIHIEQAGAPEVMQLARSPLPIPSAGQVLIRVHAAGVNGPDIKQRVGIYPPPPGASPIIGLEVAGEICALGD
GVNQWQIGDKVCALVPGGGYGEYALTYAAHCLPIPTDFSYVQAAALPETLFTVWGNLFMRAGLKAGETVLIHGGSGGIGS
TAIQLASALGAKVIATTGKDEKRDYCLGLGAHEVINYQSQNFVEAVMAFTQDKGVNVVFDIAGGDFINLNLQALAMDGRM
VSVAMQRGPKAEVELFRLMAKRIVWTGSTLRPQSVESKAAIANELQTTVWPLLDSHKIVPNIFATFPLNEAPKAHALMES
GEHRGKVVLTLV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=327, Percent_Identity=36.085626911315, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI22538444, Length=327, Percent_Identity=36.085626911315, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=33.434650455927, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=33.434650455927, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI194239676, Length=200, Percent_Identity=39.5, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI24308257, Length=328, Percent_Identity=26.219512195122, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI28557745, Length=238, Percent_Identity=31.9327731092437, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI47519420, Length=371, Percent_Identity=26.6846361185984, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI18379349, Length=316, Percent_Identity=27.5316455696203, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=26.517571884984, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI197927207, Length=200, Percent_Identity=31, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226056130, Length=110, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI226059159, Length=110, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI226059133, Length=110, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=32.0121951219512, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1788073, Length=320, Percent_Identity=26.875, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17507255, Length=249, Percent_Identity=30.5220883534137, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI212642053, Length=315, Percent_Identity=25.3968253968254, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71987554, Length=186, Percent_Identity=34.4086021505376, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536829, Length=188, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=340, Percent_Identity=28.5294117647059, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324486, Length=333, Percent_Identity=25.8258258258258, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=332, Percent_Identity=23.4939759036145, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=24.6987951807229, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=24.2603550295858, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=26.9372693726937, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221330659, Length=270, Percent_Identity=25.9259259259259, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920632, Length=270, Percent_Identity=25.9259259259259, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45550423, Length=297, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35293; Mature: 35162

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALPNDYVHIHIEQAGAPEVMQLARSPLPIPSAGQVLIRVHAAGVNGPDIKQRVGIYPP
CCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHCCCCCC
PPGASPIIGLEVAGEICALGDGVNQWQIGDKVCALVPGGGYGEYALTYAAHCLPIPTDFS
CCCCCCEEEEEECCCEEECCCCCCCEECCCEEEEEECCCCCCCHHHHHHHHEECCCCCHH
YVQAAALPETLFTVWGNLFMRAGLKAGETVLIHGGSGGIGSTAIQLASALGAKVIATTGK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCC
DEKRDYCLGLGAHEVINYQSQNFVEAVMAFTQDKGVNVVFDIAGGDFINLNLQALAMDGR
CCCCCEEECCCHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEEECCE
MVSVAMQRGPKAEVELFRLMAKRIVWTGSTLRPQSVESKAAIANELQTTVWPLLDSHKIV
EEEEEHHCCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
PNIFATFPLNEAPKAHALMESGEHRGKVVLTLV
CHHEEECCCCCCCHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure 
SALPNDYVHIHIEQAGAPEVMQLARSPLPIPSAGQVLIRVHAAGVNGPDIKQRVGIYPP
CCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHCCCCCC
PPGASPIIGLEVAGEICALGDGVNQWQIGDKVCALVPGGGYGEYALTYAAHCLPIPTDFS
CCCCCCEEEEEECCCEEECCCCCCCEECCCEEEEEECCCCCCCHHHHHHHHEECCCCCHH
YVQAAALPETLFTVWGNLFMRAGLKAGETVLIHGGSGGIGSTAIQLASALGAKVIATTGK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCC
DEKRDYCLGLGAHEVINYQSQNFVEAVMAFTQDKGVNVVFDIAGGDFINLNLQALAMDGR
CCCCCEEECCCHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEEECCE
MVSVAMQRGPKAEVELFRLMAKRIVWTGSTLRPQSVESKAAIANELQTTVWPLLDSHKIV
EEEEEHHCCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
PNIFATFPLNEAPKAHALMESGEHRGKVVLTLV
CHHEEECCCCCCCHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]