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The map label for this gene is aer [H]

Identifier: 120597478

GI number: 120597478

Start: 710532

End: 712106

Strand: Direct

Name: aer [H]

Synonym: Sputw3181_0647

Alternate gene names: 120597478

Gene position: 710532-712106 (Clockwise)

Preceding gene: 120597476

Following gene: 120597479

Centisome position: 15.09

GC content: 45.46

Gene sequence:

>1575_bases
ATGAGAAAAAACTTACCAGTTACACAGCGTGAATATGACTATCCGGCAGATTGGATTTTATTATCGACCACGGATACTCA
GAGTCATATCACCTACGCGAATGCCTCATTTTGTAAGGTCTCCGGTTATGAGCTCGATGCCATGTTAGGCCAGACCCATA
ATATGGTTCGTCATCCGGATATGCCACCACAGGCATTTGAAGATCTGTGGAAAAAAATCAAAAAAGGGGAGCCATGGAAG
GGCATCGTCAAAAACCGTTGTGCCAATGGCGATCATTATTGGGTGGATGCTTATGTATCACCTATTTCCATTAATGGCCA
AGTCGTTGAGTTTCAATCGGTACGTACTAAGCCTAGTCGCGAGCAAGTTAAGCGAGCAGAAGCTGCCTATAGTGAATTGA
ATAAAACAGGCAGTATCAAGGCATTAAAGCTTACCCTAAGTATGCCAACCAAGTTACTGCTGATCGCTTTAATTGCTTTG
CTACCTGTTTTGTACCTAGCGATTGAAGTTGGATTGGTTGGATTTATTGCTTTTATCTTTAGCTTCATTGTATTGCTTGT
GGGAGGGCATCTCGTGCTTGGTCGCTACTATGCCTTAGTTGAAAAAGCGAAGCGGATCTACGATAGCCCTCTGATGGCAC
ATATTTATAGTGGTAACTGTGATGATCTTGGCGCCATAGATTTGGCCCTACAAATGCAGAGTTCAGAGCTTAAGTCGATT
CTTGGCCGCGCATCAGACTCCTGCTATAACGTCGCTGAGCAGGCTAAAGTTTCGGCGGCTAAGGGAAAAGAAATCCAGAG
AACGAGTCAGTCTCAGCTTTCTGAAATAGAACAAGTTGCTACTGCCATGCAGCAAATGACCGCCACGTTAGGGGATATGT
CATCCAATTGCGCCGATACCGCCAGTGCGTCTCAAATGGCATCGGCCGAAACCATTAATGGTGATAAAAGGGTTGCAAGT
ACGATTAGCTCTATTCAGGCTATGGCTGAGCAGTTACAGGAGACTGCTAAGGTGATTACTCAATTAGAAAGCCACAGTAA
AGATATAGGTACTGTGCTTGACGTGATTCAGAGTATTGCGGGTCAAACTAATTTACTGGCGCTGAATGCGGCAATTGAAG
CGGCTCGAGCCGGAGAGCAGGGGCGAGGATTTGCAGTGGTGGCCGATGAAGTGCGTGCATTAGCGCAACGTACCCATGAT
GCAACTAAAGAAATTCACAGCATGATTAGCTTATTGCAGCAAGGAACCAGTAAGGCCGTTGAGAGTATGCAGCATGGCTT
AGTGGCGGCCTCACAATGTATTTCGACTGCCGATCTGGCGGGGGCTGCGCTACAAACGATTCGTGAAGCCATCGCGACTA
TCACCGATATGACTCACCACATTGCTAGTGCTGTGGAAGAACAATCGAGTGTGGCGAATGAAATGAACCGAAGTGTGGTG
AATACGGCGCAGTTTACCCATTTAAGTCATCAGCTTGGCAGTGAAATGGTGAGTTTAAATGATGATGTTATTCAAGAAAT
GGATTCCCATTCGGTATTAGTTGGTCAATTCTTAAAGCGTAGTTTTAAGGTTTAA

Upstream 100 bases:

>100_bases
CCTAGAAATGGAGTGGCAATTTTAATTAAAGATAAGCAACTGCTCAGGGTGATGCCTCATGGATGACTAAAAATATTAAT
CGTTATTCCATAAGGTGATC

Downstream 100 bases:

>100_bases
TTGCTTTAATCAAATGCGGTAGTATAAAGGCAATAAGCGTGGCTATTGCCTTTTTTATTTTAATAGCTATTAAAAATCAA
TTGGTTGGTTATAGTGATCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MRKNLPVTQREYDYPADWILLSTTDTQSHITYANASFCKVSGYELDAMLGQTHNMVRHPDMPPQAFEDLWKKIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISINGQVVEFQSVRTKPSREQVKRAEAAYSELNKTGSIKALKLTLSMPTKLLLIALIAL
LPVLYLAIEVGLVGFIAFIFSFIVLLVGGHLVLGRYYALVEKAKRIYDSPLMAHIYSGNCDDLGAIDLALQMQSSELKSI
LGRASDSCYNVAEQAKVSAAKGKEIQRTSQSQLSEIEQVATAMQQMTATLGDMSSNCADTASASQMASAETINGDKRVAS
TISSIQAMAEQLQETAKVITQLESHSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIHSMISLLQQGTSKAVESMQHGLVAASQCISTADLAGAALQTIREAIATITDMTHHIASAVEEQSSVANEMNRSVV
NTAQFTHLSHQLGSEMVSLNDDVIQEMDSHSVLVGQFLKRSFKV

Sequences:

>Translated_524_residues
MRKNLPVTQREYDYPADWILLSTTDTQSHITYANASFCKVSGYELDAMLGQTHNMVRHPDMPPQAFEDLWKKIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISINGQVVEFQSVRTKPSREQVKRAEAAYSELNKTGSIKALKLTLSMPTKLLLIALIAL
LPVLYLAIEVGLVGFIAFIFSFIVLLVGGHLVLGRYYALVEKAKRIYDSPLMAHIYSGNCDDLGAIDLALQMQSSELKSI
LGRASDSCYNVAEQAKVSAAKGKEIQRTSQSQLSEIEQVATAMQQMTATLGDMSSNCADTASASQMASAETINGDKRVAS
TISSIQAMAEQLQETAKVITQLESHSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIHSMISLLQQGTSKAVESMQHGLVAASQCISTADLAGAALQTIREAIATITDMTHHIASAVEEQSSVANEMNRSVV
NTAQFTHLSHQLGSEMVSLNDDVIQEMDSHSVLVGQFLKRSFKV
>Mature_524_residues
MRKNLPVTQREYDYPADWILLSTTDTQSHITYANASFCKVSGYELDAMLGQTHNMVRHPDMPPQAFEDLWKKIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISINGQVVEFQSVRTKPSREQVKRAEAAYSELNKTGSIKALKLTLSMPTKLLLIALIAL
LPVLYLAIEVGLVGFIAFIFSFIVLLVGGHLVLGRYYALVEKAKRIYDSPLMAHIYSGNCDDLGAIDLALQMQSSELKSI
LGRASDSCYNVAEQAKVSAAKGKEIQRTSQSQLSEIEQVATAMQQMTATLGDMSSNCADTASASQMASAETINGDKRVAS
TISSIQAMAEQLQETAKVITQLESHSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIHSMISLLQQGTSKAVESMQHGLVAASQCISTADLAGAALQTIREAIATITDMTHHIASAVEEQSSVANEMNRSVV
NTAQFTHLSHQLGSEMVSLNDDVIQEMDSHSVLVGQFLKRSFKV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=493, Percent_Identity=31.4401622718053, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1787690, Length=294, Percent_Identity=30.952380952381, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI2367378, Length=297, Percent_Identity=31.986531986532, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1788195, Length=211, Percent_Identity=36.9668246445498, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=251, Percent_Identity=35.4581673306773, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56978; Mature: 56978

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLPVTQREYDYPADWILLSTTDTQSHITYANASFCKVSGYELDAMLGQTHNMVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEECCCHHHHHHHHHHHHCCCCC
MPPQAFEDLWKKIKKGEPWKGIVKNRCANGDHYWVDAYVSPISINGQVVEFQSVRTKPSR
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCEECCCEEEEHHHHCCCCCH
EQVKRAEAAYSELNKTGSIKALKLTLSMPTKLLLIALIALLPVLYLAIEVGLVGFIAFIF
HHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFIVLLVGGHLVLGRYYALVEKAKRIYDSPLMAHIYSGNCDDLGAIDLALQMQSSELKSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
LGRASDSCYNVAEQAKVSAAKGKEIQRTSQSQLSEIEQVATAMQQMTATLGDMSSNCADT
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ASASQMASAETINGDKRVASTISSIQAMAEQLQETAKVITQLESHSKDIGTVLDVIQSIA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
GQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHDATKEIHSMISLLQQGTSKAV
CCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESMQHGLVAASQCISTADLAGAALQTIREAIATITDMTHHIASAVEEQSSVANEMNRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTAQFTHLSHQLGSEMVSLNDDVIQEMDSHSVLVGQFLKRSFKV
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKNLPVTQREYDYPADWILLSTTDTQSHITYANASFCKVSGYELDAMLGQTHNMVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEECCCHHHHHHHHHHHHCCCCC
MPPQAFEDLWKKIKKGEPWKGIVKNRCANGDHYWVDAYVSPISINGQVVEFQSVRTKPSR
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCEECCCEEEEHHHHCCCCCH
EQVKRAEAAYSELNKTGSIKALKLTLSMPTKLLLIALIALLPVLYLAIEVGLVGFIAFIF
HHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFIVLLVGGHLVLGRYYALVEKAKRIYDSPLMAHIYSGNCDDLGAIDLALQMQSSELKSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
LGRASDSCYNVAEQAKVSAAKGKEIQRTSQSQLSEIEQVATAMQQMTATLGDMSSNCADT
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ASASQMASAETINGDKRVASTISSIQAMAEQLQETAKVITQLESHSKDIGTVLDVIQSIA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
GQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHDATKEIHSMISLLQQGTSKAV
CCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESMQHGLVAASQCISTADLAGAALQTIREAIATITDMTHHIASAVEEQSSVANEMNRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTAQFTHLSHQLGSEMVSLNDDVIQEMDSHSVLVGQFLKRSFKV
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]