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The map label for this gene is murG

Identifier: 120597221

GI number: 120597221

Start: 421987

End: 423075

Strand: Direct

Name: murG

Synonym: Sputw3181_0390

Alternate gene names: 120597221

Gene position: 421987-423075 (Clockwise)

Preceding gene: 120597220

Following gene: 120597222

Centisome position: 8.96

GC content: 48.85

Gene sequence:

>1089_bases
ATGACCCAAGAGGGTAAACGTATTCTAGTCATGGCAGGTGGTACGGGCGGGCATGTCTTCCCGGCACTAGCGGTGGCCAA
GTATTTAGCGCAACAGGGATGGCAAGTCCGTTGGTTGGGCACGGCCGATCGTATGGAAGCGCGTTTAGTACCGCAATACG
GATTTGATATTGATTTTATTGATATCAAAGGGGTTCGTGGTAATGGTTTGGTTCGCAAATTGGCTGCCCCTTTTAAAGTG
ATCCGCTCTATCTTGCAGGCCAAAGCTGTGATAGCGGAATTTAAACCAGATGTCGTGCTAGGCATGGGTGGTTTTGCCAG
TGGGCCTGGTGGCGTTGCAGCAAGACTTGCGGGTATTCCGTTAGTGTTGCATGAACAAAATGCGATTCCTGGTATGACGA
ATAAGTTGCTCTCTCGTATCGCAACTCAAGTGTTATGTGCTTTTAAAAACACCTTTACCACAGTGAAATCCAAGGTAGTG
GGCAATCCCATTCGGCGTGAGCTAATCGCGCTAGGCGCTGAGCCAAAACCCCTTGCCGATGATGCTTTAAAAGTGCTTGT
GGTGGGTGGAAGCCTAGGCGCCAAAATATTTAACGATTTAATGCCTTCTGTGGTGGCGGCCTTAAGTAAGCAGCAATCTA
TTACCGTTTGGCATCAGGTAGGTAAAGATAATTTAGCAGGTGTAAAAGCGGCATATCAGCAACAAGGACAAGAGGGTGGG
GTCAACATTGCTGAATTTATTGATGATATGGAAGCCGCCTACCGTTGGGCCGATGTGGTGCTATGCCGAGCAGGTGCACT
AACAGTATCAGAGCTAGCCGCGGTGGGATTACCGAGTATTTTGGTGCCCTATCCCCATGCGGTGGATGATCACCAAACAC
GTAACGGTCAAGTATTGGTTGAGGCTGGCGCTGCTTTCCTATTGCCGCAAGCCATCTTGGACGTAGATAAGCTAGTGGGT
AAATTACAATTGCTCGCTAATGACAGAACAGAATTAGCCCGTATGGGCCAAAGAGCAAGAGACGTTGCAGTACTGGATGC
CACAGAACAAGTTGCAGCCGTGTGCATTAGCCTTGCTGAGAAAGGATAA

Upstream 100 bases:

>100_bases
GTAGTTTATGGGTCATGACGGCGGCGGCAATGACATTGCTACGCATTGATTATGAACGGCGCATGAGTTTAGTTCAGGCC
GTGCAAGGGAGATTGAAGTA

Downstream 100 bases:

>100_bases
GCATGACTAAAACAGAAAGATACATACAGCTAAGAAGCATGATCCCCGAAATGCGCCGTATTAAGCGTATTCACTTCGTC
GGCATTGGCGGCGCGGGCAT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTQEGKRILVMAGGTGGHVFPALAVAKYLAQQGWQVRWLGTADRMEARLVPQYGFDIDFIDIKGVRGNGLVRKLAAPFKV
IRSILQAKAVIAEFKPDVVLGMGGFASGPGGVAARLAGIPLVLHEQNAIPGMTNKLLSRIATQVLCAFKNTFTTVKSKVV
GNPIRRELIALGAEPKPLADDALKVLVVGGSLGAKIFNDLMPSVVAALSKQQSITVWHQVGKDNLAGVKAAYQQQGQEGG
VNIAEFIDDMEAAYRWADVVLCRAGALTVSELAAVGLPSILVPYPHAVDDHQTRNGQVLVEAGAAFLLPQAILDVDKLVG
KLQLLANDRTELARMGQRARDVAVLDATEQVAAVCISLAEKG

Sequences:

>Translated_362_residues
MTQEGKRILVMAGGTGGHVFPALAVAKYLAQQGWQVRWLGTADRMEARLVPQYGFDIDFIDIKGVRGNGLVRKLAAPFKV
IRSILQAKAVIAEFKPDVVLGMGGFASGPGGVAARLAGIPLVLHEQNAIPGMTNKLLSRIATQVLCAFKNTFTTVKSKVV
GNPIRRELIALGAEPKPLADDALKVLVVGGSLGAKIFNDLMPSVVAALSKQQSITVWHQVGKDNLAGVKAAYQQQGQEGG
VNIAEFIDDMEAAYRWADVVLCRAGALTVSELAAVGLPSILVPYPHAVDDHQTRNGQVLVEAGAAFLLPQAILDVDKLVG
KLQLLANDRTELARMGQRARDVAVLDATEQVAAVCISLAEKG
>Mature_361_residues
TQEGKRILVMAGGTGGHVFPALAVAKYLAQQGWQVRWLGTADRMEARLVPQYGFDIDFIDIKGVRGNGLVRKLAAPFKVI
RSILQAKAVIAEFKPDVVLGMGGFASGPGGVAARLAGIPLVLHEQNAIPGMTNKLLSRIATQVLCAFKNTFTTVKSKVVG
NPIRRELIALGAEPKPLADDALKVLVVGGSLGAKIFNDLMPSVVAALSKQQSITVWHQVGKDNLAGVKAAYQQQGQEGGV
NIAEFIDDMEAAYRWADVVLCRAGALTVSELAAVGLPSILVPYPHAVDDHQTRNGQVLVEAGAAFLLPQAILDVDKLVGK
LQLLANDRTELARMGQRARDVAVLDATEQVAAVCISLAEKG

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=354, Percent_Identity=53.3898305084746, Blast_Score=354, Evalue=6e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38422; Mature: 38291

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEGKRILVMAGGTGGHVFPALAVAKYLAQQGWQVRWLGTADRMEARLVPQYGFDIDFI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHEECCCCCCCEEEE
DIKGVRGNGLVRKLAAPFKVIRSILQAKAVIAEFKPDVVLGMGGFASGPGGVAARLAGIP
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCE
LVLHEQNAIPGMTNKLLSRIATQVLCAFKNTFTTVKSKVVGNPIRRELIALGAEPKPLAD
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
DALKVLVVGGSLGAKIFNDLMPSVVAALSKQQSITVWHQVGKDNLAGVKAAYQQQGQEGG
HCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCC
VNIAEFIDDMEAAYRWADVVLCRAGALTVSELAAVGLPSILVPYPHAVDDHQTRNGQVLV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHCCCCCCCCCCCCCCCCEEEE
EAGAAFLLPQAILDVDKLVGKLQLLANDRTELARMGQRARDVAVLDATEQVAAVCISLAE
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHC
KG
CC
>Mature Secondary Structure 
TQEGKRILVMAGGTGGHVFPALAVAKYLAQQGWQVRWLGTADRMEARLVPQYGFDIDFI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHEECCCCCCCEEEE
DIKGVRGNGLVRKLAAPFKVIRSILQAKAVIAEFKPDVVLGMGGFASGPGGVAARLAGIP
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCE
LVLHEQNAIPGMTNKLLSRIATQVLCAFKNTFTTVKSKVVGNPIRRELIALGAEPKPLAD
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
DALKVLVVGGSLGAKIFNDLMPSVVAALSKQQSITVWHQVGKDNLAGVKAAYQQQGQEGG
HCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCC
VNIAEFIDDMEAAYRWADVVLCRAGALTVSELAAVGLPSILVPYPHAVDDHQTRNGQVLV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHCCCCCCCCCCCCCCCCEEEE
EAGAAFLLPQAILDVDKLVGKLQLLANDRTELARMGQRARDVAVLDATEQVAAVCISLAE
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHC
KG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA