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The map label for this gene is ftsW [H]

Identifier: 120597220

GI number: 120597220

Start: 420776

End: 421987

Strand: Direct

Name: ftsW [H]

Synonym: Sputw3181_0389

Alternate gene names: 120597220

Gene position: 420776-421987 (Clockwise)

Preceding gene: 120597219

Following gene: 120597221

Centisome position: 8.94

GC content: 46.45

Gene sequence:

>1212_bases
ATGGCGAGTGATACAAGGCAATTCAGCCTGTTTGGTCGCTTGCTATCCGCAATGCCAAACTGGCAACGTGATACTGAAGT
GCCGGGCGTGCAATTGTACGACCGTGCTTTGTTCACGGCTGTATTGTCTTTAATCGCTTTTGGTTTTGTGATGGTGATGT
CGGCATCGATGCCAGAGGCTCAAACGCTAACCGGAAATCCGTTTCACTTTATGACTCGCCATGTGGGTTATTTAATGGGT
TGTTTTGTCATTGCGGCTTTCGTGCTACGGGTAGATATGCAAACTTGGCAGCGTTTGAGTCCAATCATGCTGTTAGTTGT
CGGTTTGATGTTGGTTGCAGTGTTACTGGTGGGTACCACAGTTAATGGTGCCACGCGCTGGTTATCTATCGGGCCTATTC
GTATTCAAGTCGCAGAGTTGGCTAAGTTTGCTTTCTCTGTGTATATGGCAGGTTATCTTGTGCGTCGGCATCAAGAAGTT
CGTGAAAATGCGAAGGGTTTCTATAAGCCAATAGCTGTGTTCGCGATTTACGCCATTTTGATCTTAATGCAACCTGACTT
AGGTACAGTCGTGGTGCTATTCGTTGGAACAGTGGGGTTATTGTTCCTTGCCGGTGCGCGGTTACTCGATTTCTTTGCAC
TGATTTTTACTGGGGTTTTAGCCTTCGTTGCGCTGGTATTACTCGAACCTTACCGTATGCGCCGTGTCACCTCATTTATG
GATCCTTGGCAAGATCCCTTTGGCAGTGGTTATCAGTTAACCCAATCTTTAATGGCCTATGGCCGTGGCGATTGGTTTGG
TCAGGGGTTAGGTAATAGTATTCAAAAATTAGAATATTTGCCCGAAGCCCATACCGACTTTATCTTTGCTGTTATAGGGG
AAGAGTTAGGTTTTATCGGCATTATTGCAGTGTTATCCGTGTTGCTGTTTGTGGCATTGAGGGCCATTCGCCTCGGCAAT
TTATGCCTAGTGATGGACAAAGCCTTCGAAGGTTATCTGGCCTATGCCATCGGCATTTGGATCTGTTTTCAGACCGTCGT
TAATGTGGGAGCAAGCATTGGTATGTTACCTACTAAAGGGTTAACACTGCCCTTTGTAAGTTACGGTGGTAGTAGTTTAT
GGGTCATGACGGCGGCGGCAATGACATTGCTACGCATTGATTATGAACGGCGCATGAGTTTAGTTCAGGCCGTGCAAGGG
AGATTGAAGTAA

Upstream 100 bases:

>100_bases
GGCGATATCGTTTTATTATCTCCCGCCTGTGCGAGTCTAGATATGTACAGTAACTTTATGGCGCGTGGCGATGATTTCCG
CAATCTGGTGGAGCTGCTCG

Downstream 100 bases:

>100_bases
TGACCCAAGAGGGTAAACGTATTCTAGTCATGGCAGGTGGTACGGGCGGGCATGTCTTCCCGGCACTAGCGGTGGCCAAG
TATTTAGCGCAACAGGGATG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MASDTRQFSLFGRLLSAMPNWQRDTEVPGVQLYDRALFTAVLSLIAFGFVMVMSASMPEAQTLTGNPFHFMTRHVGYLMG
CFVIAAFVLRVDMQTWQRLSPIMLLVVGLMLVAVLLVGTTVNGATRWLSIGPIRIQVAELAKFAFSVYMAGYLVRRHQEV
RENAKGFYKPIAVFAIYAILILMQPDLGTVVVLFVGTVGLLFLAGARLLDFFALIFTGVLAFVALVLLEPYRMRRVTSFM
DPWQDPFGSGYQLTQSLMAYGRGDWFGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIIAVLSVLLFVALRAIRLGN
LCLVMDKAFEGYLAYAIGIWICFQTVVNVGASIGMLPTKGLTLPFVSYGGSSLWVMTAAAMTLLRIDYERRMSLVQAVQG
RLK

Sequences:

>Translated_403_residues
MASDTRQFSLFGRLLSAMPNWQRDTEVPGVQLYDRALFTAVLSLIAFGFVMVMSASMPEAQTLTGNPFHFMTRHVGYLMG
CFVIAAFVLRVDMQTWQRLSPIMLLVVGLMLVAVLLVGTTVNGATRWLSIGPIRIQVAELAKFAFSVYMAGYLVRRHQEV
RENAKGFYKPIAVFAIYAILILMQPDLGTVVVLFVGTVGLLFLAGARLLDFFALIFTGVLAFVALVLLEPYRMRRVTSFM
DPWQDPFGSGYQLTQSLMAYGRGDWFGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIIAVLSVLLFVALRAIRLGN
LCLVMDKAFEGYLAYAIGIWICFQTVVNVGASIGMLPTKGLTLPFVSYGGSSLWVMTAAAMTLLRIDYERRMSLVQAVQG
RLK
>Mature_402_residues
ASDTRQFSLFGRLLSAMPNWQRDTEVPGVQLYDRALFTAVLSLIAFGFVMVMSASMPEAQTLTGNPFHFMTRHVGYLMGC
FVIAAFVLRVDMQTWQRLSPIMLLVVGLMLVAVLLVGTTVNGATRWLSIGPIRIQVAELAKFAFSVYMAGYLVRRHQEVR
ENAKGFYKPIAVFAIYAILILMQPDLGTVVVLFVGTVGLLFLAGARLLDFFALIFTGVLAFVALVLLEPYRMRRVTSFMD
PWQDPFGSGYQLTQSLMAYGRGDWFGQGLGNSIQKLEYLPEAHTDFIFAVIGEELGFIGIIAVLSVLLFVALRAIRLGNL
CLVMDKAFEGYLAYAIGIWICFQTVVNVGASIGMLPTKGLTLPFVSYGGSSLWVMTAAAMTLLRIDYERRMSLVQAVQGR
LK

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=393, Percent_Identity=55.7251908396947, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1786853, Length=334, Percent_Identity=31.7365269461078, Blast_Score=144, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44650; Mature: 44519

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASDTRQFSLFGRLLSAMPNWQRDTEVPGVQLYDRALFTAVLSLIAFGFVMVMSASMPEA
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC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CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]