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The map label for this gene is acoR [H]

Identifier: 120597047

GI number: 120597047

Start: 238100

End: 240001

Strand: Direct

Name: acoR [H]

Synonym: Sputw3181_0215

Alternate gene names: 120597047

Gene position: 238100-240001 (Clockwise)

Preceding gene: 120597045

Following gene: 120597050

Centisome position: 5.06

GC content: 49.0

Gene sequence:

>1902_bases
ATGACAGTTAAACCGCATTTACCATCGACACAGGCGTGGTTGGCCGATTCGTGGCAGCGCAGCATTGGCGCTGGCTTGTC
AGAATTTCAGTTACCCCAGGAGCTCAGGCTCGATGCTAGTGAACTAAAGCAGAAACATGAGCAATATCAAATGCTCATCG
CATTAGTGCAATCCCATGCCTTGCCTTTGTTCAATCAGTTGATGGCGCATTCTAATAGCCGACTCCTGCTCAGCGATGCC
GAGGGTTATGTGCTTAGGCATTGGGGCGTGAGCCGTTACTCTACAAAACTGGCGGACGTGGCTTTGGATATTGGGGTGAA
TTGGCTTGAGCAGCACAAGGGCACCAATGCGATAGGGACGGCACTCACCGCCAAACAAGCAGTATCTGTGGTGGGTGAGC
AACATTTTATTCGCCAGAATCGTTTTATGAGTTGCACTGCTTGCCCGATATTTTCCCCCCAAGGTGAGATGCTCGGGGTG
ATTGATATCACCAGCGAGCAGCAAAGGCACACCCAGCAGACGCTAATGTTAGTGTCCAGTTTGGCACAGCAGGTCGAGAC
CGCGCTTTTGTGCCATCTGCCCGATAGCCATTATCGAATCGATTTAGCTGCGCAACCCAATCTGCTCAATTCGGGTTGGC
AGGGTATAGTGATTGCCGATAGCGATGGCCGCATCGTGGGTTGTAATCCCATGGCGAAACAATTACTTAATCATGCCAAG
GTGGGCGATGCTGTCGAACAGTACTTAGGCGATAATTGGAGCCGTGTGGGTGGCTTTAATCAACATTTAGCTTTGCATTT
ACAGACTCAATCCTTAAATATTCCCAGCGCTAAGGGTCGAGTTGCGATTAGCAATAAATCGCTCAATCAATTGGGGGTTC
GGTTTCGCGATCCTCAATTAGAACGCGCTTGGCAACATGCCAATAAGGTGATCACCAAGCAAATTCCGCTGTTAGTGCTC
GGAGAAACGGGCGTCGGTAAAGAGCAGTTTGTTAAAAAGCTCCATGCCCAGAGTGCACGTCGCACCGAGCCTTTAGTGGC
AGTGAACTGCGCCGCATTGCCCGCTGAATTAGTCGAATCTGAACTTTTTGGTTATCAGGCAGGCGCTTTTACTGGGGCAA
ACCGCACTGGATTTATCGGTAAAATTCGCCAAGCCCACGGTGGCTTTTTGTTTTTAGATGAGATCGGTGAAATGCCGCTG
GCGGCCCAGAGTCGTTTACTCAGAGTATTGCAAGAGCGCGAAGTGGTACCCGTTGGCAGTAATCAAAGCTTTAAAGTCGA
TATCCAAATCATTGCCGCAACCCATATGGATTTAGAACAACAGGTGACTCAAGGGCTGTTTCGACAGGATTTGTTCTATC
GATTGAATGGCTTGCAGGTGCGTTTACCTGCGCTGCGTGAACGGCAGGATATCGAGCGTATTATCCATAAATTACACCGT
AAACATCGTATTGCTGCGCAGGATATCTGCCCTGAATTGTTAGGACAAATGATGCAATACGACTGGCCGGGGAATTTGCG
CGAGCTGGATAATCTCATGCAAGTCGCTTGCTTGATGGCAGAAGGGGACAATACCCTCAATTGGCAACATTTACCCGATT
ATCTGGCGGCCAAACTCACATGCGAGCCGTTAAAAGGAGACCTGTTACAAGCTGCATCTTTATGTGATGAATTTAAAGAG
GTAAGCCGTCAACGTTCTGCATCACCCCTGCCAAGTGGTAAGCTCGCTGTGGAGCCGAATGTCACAAAGGTTCAATCGGA
TTCCCTAAATGAGGCGATTTATAGCAATGTGCTGCAGGCATTTCAGGCCTGTAATGGCAATGTGAGCCAATGCGCTAAAC
GCTTAGGGATCAGCCGTAATGCCTTGTATCGTAAGTTGAAACAGATGGGACTTAAAGCTTAG

Upstream 100 bases:

>100_bases
ATGGGCACTCAGGGATAGGAGTGTGTCCTGTGGTTACTTTGTCATTGAGTGGCACACAGCAATTGTGCCGAAACGGAACA
CAGCTCGGGGGGGCACGGTT

Downstream 100 bases:

>100_bases
CCATAAGGGTAAGCTTTAATCCCATGTCGATTGATTTAAGGTTTAAACGGGTAGGGTAATATTGACTTCAAGCCCATGTG
GTACTCTATTCTTCGCCTTA

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MTVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHALPLFNQLMAHSNSRLLLSDA
EGYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGV
IDITSEQQRHTQQTLMLVSSLAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNHAK
VGDAVEQYLGDNWSRVGGFNQHLALHLQTQSLNIPSAKGRVAISNKSLNQLGVRFRDPQLERAWQHANKVITKQIPLLVL
GETGVGKEQFVKKLHAQSARRTEPLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPL
AAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLEQQVTQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
KHRIAAQDICPELLGQMMQYDWPGNLRELDNLMQVACLMAEGDNTLNWQHLPDYLAAKLTCEPLKGDLLQAASLCDEFKE
VSRQRSASPLPSGKLAVEPNVTKVQSDSLNEAIYSNVLQAFQACNGNVSQCAKRLGISRNALYRKLKQMGLKA

Sequences:

>Translated_633_residues
MTVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHALPLFNQLMAHSNSRLLLSDA
EGYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGV
IDITSEQQRHTQQTLMLVSSLAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNHAK
VGDAVEQYLGDNWSRVGGFNQHLALHLQTQSLNIPSAKGRVAISNKSLNQLGVRFRDPQLERAWQHANKVITKQIPLLVL
GETGVGKEQFVKKLHAQSARRTEPLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPL
AAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLEQQVTQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
KHRIAAQDICPELLGQMMQYDWPGNLRELDNLMQVACLMAEGDNTLNWQHLPDYLAAKLTCEPLKGDLLQAASLCDEFKE
VSRQRSASPLPSGKLAVEPNVTKVQSDSLNEAIYSNVLQAFQACNGNVSQCAKRLGISRNALYRKLKQMGLKA
>Mature_632_residues
TVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHALPLFNQLMAHSNSRLLLSDAE
GYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVI
DITSEQQRHTQQTLMLVSSLAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNHAKV
GDAVEQYLGDNWSRVGGFNQHLALHLQTQSLNIPSAKGRVAISNKSLNQLGVRFRDPQLERAWQHANKVITKQIPLLVLG
ETGVGKEQFVKKLHAQSARRTEPLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLA
AQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLEQQVTQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHRK
HRIAAQDICPELLGQMMQYDWPGNLRELDNLMQVACLMAEGDNTLNWQHLPDYLAAKLTCEPLKGDLLQAASLCDEFKEV
SRQRSASPLPSGKLAVEPNVTKVQSDSLNEAIYSNVLQAFQACNGNVSQCAKRLGISRNALYRKLKQMGLKA

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=505, Percent_Identity=31.4851485148515, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1790437, Length=346, Percent_Identity=35.8381502890173, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1790299, Length=340, Percent_Identity=39.1176470588235, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI87082117, Length=362, Percent_Identity=37.5690607734807, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1786524, Length=347, Percent_Identity=37.463976945245, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1788550, Length=339, Percent_Identity=36.8731563421829, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1788905, Length=345, Percent_Identity=35.9420289855072, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI1789087, Length=323, Percent_Identity=36.5325077399381, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87082152, Length=347, Percent_Identity=34.0057636887608, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787583, Length=341, Percent_Identity=31.9648093841642, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI87081872, Length=205, Percent_Identity=40.9756097560976, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1789828, Length=286, Percent_Identity=35.3146853146853, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI87081858, Length=613, Percent_Identity=23.9804241435563, Blast_Score=135, Evalue=9e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70448; Mature: 70317

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHA
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCC
LPLFNQLMAHSNSRLLLSDAEGYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGT
CHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHCCCCCHHHH
ALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVIDITSEQQRHTQQTLMLVSS
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
LAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNHAK
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEECCHHHHHHHHHHH
VGDAVEQYLGDNWSRVGGFNQHLALHLQTQSLNIPSAKGRVAISNKSLNQLGVRFRDPQL
HHHHHHHHHCCCCHHHCCCCCEEEEEEEECCCCCCCCCCEEEECCCCHHHCCCCCCCCHH
ERAWQHANKVITKQIPLLVLGETGVGKEQFVKKLHAQSARRTEPLVAVNCAALPAELVES
HHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHH
ELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREVVPVGS
HHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCEECCC
NQSFKVDIQIIAATHMDLEQQVTQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
CCCEEEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHH
KHRIAAQDICPELLGQMMQYDWPGNLRELDNLMQVACLMAEGDNTLNWQHLPDYLAAKLT
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCHHHHHHHCC
CEPLKGDLLQAASLCDEFKEVSRQRSASPLPSGKLAVEPNVTKVQSDSLNEAIYSNVLQA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
FQACNGNVSQCAKRLGISRNALYRKLKQMGLKA
HHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHA
CCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCC
LPLFNQLMAHSNSRLLLSDAEGYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGT
CHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHCCCCCHHHH
ALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVIDITSEQQRHTQQTLMLVSS
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
LAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNHAK
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEECCHHHHHHHHHHH
VGDAVEQYLGDNWSRVGGFNQHLALHLQTQSLNIPSAKGRVAISNKSLNQLGVRFRDPQL
HHHHHHHHHCCCCHHHCCCCCEEEEEEEECCCCCCCCCCEEEECCCCHHHCCCCCCCCHH
ERAWQHANKVITKQIPLLVLGETGVGKEQFVKKLHAQSARRTEPLVAVNCAALPAELVES
HHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHH
ELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREVVPVGS
HHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCEECCC
NQSFKVDIQIIAATHMDLEQQVTQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
CCCEEEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHH
KHRIAAQDICPELLGQMMQYDWPGNLRELDNLMQVACLMAEGDNTLNWQHLPDYLAAKLT
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCHHHHHHHCC
CEPLKGDLLQAASLCDEFKEVSRQRSASPLPSGKLAVEPNVTKVQSDSLNEAIYSNVLQA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
FQACNGNVSQCAKRLGISRNALYRKLKQMGLKA
HHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]