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The map label for this gene is nfuA [H]

Identifier: 120596952

GI number: 120596952

Start: 146468

End: 147046

Strand: Direct

Name: nfuA [H]

Synonym: Sputw3181_0119

Alternate gene names: 120596952

Gene position: 146468-147046 (Clockwise)

Preceding gene: 120596951

Following gene: 120596957

Centisome position: 3.11

GC content: 44.56

Gene sequence:

>579_bases
ATGATTACGATTTCCGATGCGGCCCAAGCCCATTTTGTTAAGTTGTTAGCAGATCAACCTGAAGGCACTCATATTCGTGT
ATTTGTGATAAGTCCTGGTACCGCGCAAGCAGAGTGTGGTGTGTCCTATTGTCCACCTGATGCGGTTGAAAGTGATGATA
TTGAACTTGAGTTCAATGGCTTTAACGCTATGGTTGATGAAAAGAGCGCACCTTTCCTTGAAGAAGCAACAATCGATTTT
GTGACCGATCAATTAGGTTCGCAACTCACACTTAAAGCGCCTAACGCCAAAATGCGTAAAGTATCAGGCGATGCGCCTTT
AGTTGAACGTATTGAATATGTTATTCAATCTGAAATTAACCCGCAGTTGGCCAGCCATGGCGGTAACATCATGTTGGTTG
AAATCACCAGCGAAGGTGTTGCGGTATTGCAGTTTGGCGGCGGTTGTAACGGTTGTTCTCAAGTGGATATCACCTTAAAG
GATGGTATCGAAAAACAACTGTTAGACATGTTCCCCGGTGAATTAACCGGTGTGCGTGACGTAACTGATCACCAACACGG
TGAGCATTCTTACGCTTAA

Upstream 100 bases:

>100_bases
AACTTGGTATTCAAGGGACTACAAAGCGGGAGTGAGTCGGAGTATCATACGGCTAATTCTTACTAAAACACTCAGGTATC
CCCTGACGGAGCTGGTTTCC

Downstream 100 bases:

>100_bases
TCTTTTGAGTTGAGCAAATAAAAAACGCGACCCGGAGTCGCGTTTTTTATATCTCTTAATTTGTACTAACTCATGCACGA
ACTGACAGTTTTGATTATTT

Product: putative DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTAQAECGVSYCPPDAVESDDIELEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEINPQLASHGGNIMLVEITSEGVAVLQFGGGCNGCSQVDITLK
DGIEKQLLDMFPGELTGVRDVTDHQHGEHSYA

Sequences:

>Translated_192_residues
MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTAQAECGVSYCPPDAVESDDIELEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEINPQLASHGGNIMLVEITSEGVAVLQFGGGCNGCSQVDITLK
DGIEKQLLDMFPGELTGVRDVTDHQHGEHSYA
>Mature_192_residues
MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTAQAECGVSYCPPDAVESDDIELEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEINPQLASHGGNIMLVEITSEGVAVLQFGGGCNGCSQVDITLK
DGIEKQLLDMFPGELTGVRDVTDHQHGEHSYA

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins [H]

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family [H]

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=74.869109947644, Blast_Score=301, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- ProDom:   PD002830 [H]

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU [H]

EC number: NA

Molecular weight: Translated: 20661; Mature: 20661

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTAQAECGVSYCPPDAVESDDIELEFNG
CEEECCHHHHHHHHHECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECC
FNAMVDEKSAPFLEEATIDFVTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEIN
CEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCC
PQLASHGGNIMLVEITSEGVAVLQFGGGCNGCSQVDITLKDGIEKQLLDMFPGELTGVRD
HHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEEHHCCHHHHHHHHCCCCCCCCCC
VTDHQHGEHSYA
CCCCCCCCCCCC
>Mature Secondary Structure
MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTAQAECGVSYCPPDAVESDDIELEFNG
CEEECCHHHHHHHHHECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECC
FNAMVDEKSAPFLEEATIDFVTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEIN
CEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCC
PQLASHGGNIMLVEITSEGVAVLQFGGGCNGCSQVDITLKDGIEKQLLDMFPGELTGVRD
HHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEEHHCCHHHHHHHHCCCCCCCCCC
VTDHQHGEHSYA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA