Click here to switch to the map view.

The map label for this gene is mdcB [H]

Identifier: 119947260

GI number: 119947260

Start: 4470397

End: 4471275

Strand: Reverse

Name: mdcB [H]

Synonym: Ping_3658

Alternate gene names: 119947260

Gene position: 4471275-4470397 (Counterclockwise)

Preceding gene: 119947261

Following gene: 119947259

Centisome position: 98.06

GC content: 45.51

Gene sequence:

>879_bases
ATGGATAATTTATTAATAGATAACGACGCGACTTGGACTTGTTTGAAAATAGCTCAATTAGCGCAATGGGCGCTGCAGGA
AGAAGTTCTTCTGACGCCTAAGCCGGGTTTAGTGGATGCTGCGGATAATGGTGCGCATCGAGATCTAAGCCTTGAACTAA
TGCTCTTATCCGCGCAGACATTAACCCCTTATTTTACTGAGATGTCATCCGTTGCATGGGGGCAGCCAACGGGTAAATTA
TTGCGTGAAAAGATAGGGGAGATTGGCCGTGACGCCGAGTCAGCTATGTTATTAGCTACCCGGCAAGTGAACACACACCG
CGGTGCGATCTGGGCACTGGGTCTTATCAGCGCCGCGGCTGCACAAAATAATAGACAGTCCGATGCTGTCAGTTTATGCG
CGCGAGCCGGTGCTATTGCGAGGTTAAATGATAAGTATATCCCTATTACCTTTAGTAAAGGTAAGAGTGCTTGTCAGCGT
TATCAGGTCACTGGGGCGAAAGAAGAAGCACAACAGGGATTTCCCAGTATTATCAAATTAGCTTTACCAACATTACGAGC
AAGCCGAGCGAAGGGTGACAGTGAACAAGCCGCGCGTCTCAATGCTTTATTAGTATTGATGGCAAATATTAATGATACCT
GTGTCTTATCCCGGGGCGGGGAAAATGCATTATTGACTGTCCAACATTTTTGCCAGGAAATTATAGATGGTGGCGGCGTG
GCAGCAGAAAATGGCATGTCTCAGCTGCTTAAATTAGGCGAAATCATGATTGAAGGCAATCTTTCACCAGGTGGTGCGGC
TGATTTGTTATCGGCAACGTTATTTATTGATGCACTAGAAAATAAATTAATTTCGAGGTTCCACTATGCAACCAATTAA

Upstream 100 bases:

>100_bases
AGGCGAATCGCAGCTTGCTTGCGGCTAAAAATGTCAGTGAATTGGTTCAATGGTCCGAAGGACTGTATCAGCCACCTGCT
AAATACAGAAGTTGGTGATT

Downstream 100 bases:

>100_bases
ACTTTTTTTTGAAGGAAATGAAACCATATCGGACTCAGTGCGTGTTGGTAATGTAGGGTCGGGTGATCTTGAAGTTATTT
TTTTACCCGCTTCGAGCAAT

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDNLLIDNDATWTCLKIAQLAQWALQEEVLLTPKPGLVDAADNGAHRDLSLELMLLSAQTLTPYFTEMSSVAWGQPTGKL
LREKIGEIGRDAESAMLLATRQVNTHRGAIWALGLISAAAAQNNRQSDAVSLCARAGAIARLNDKYIPITFSKGKSACQR
YQVTGAKEEAQQGFPSIIKLALPTLRASRAKGDSEQAARLNALLVLMANINDTCVLSRGGENALLTVQHFCQEIIDGGGV
AAENGMSQLLKLGEIMIEGNLSPGGAADLLSATLFIDALENKLISRFHYATN

Sequences:

>Translated_292_residues
MDNLLIDNDATWTCLKIAQLAQWALQEEVLLTPKPGLVDAADNGAHRDLSLELMLLSAQTLTPYFTEMSSVAWGQPTGKL
LREKIGEIGRDAESAMLLATRQVNTHRGAIWALGLISAAAAQNNRQSDAVSLCARAGAIARLNDKYIPITFSKGKSACQR
YQVTGAKEEAQQGFPSIIKLALPTLRASRAKGDSEQAARLNALLVLMANINDTCVLSRGGENALLTVQHFCQEIIDGGGV
AAENGMSQLLKLGEIMIEGNLSPGGAADLLSATLFIDALENKLISRFHYATN
>Mature_292_residues
MDNLLIDNDATWTCLKIAQLAQWALQEEVLLTPKPGLVDAADNGAHRDLSLELMLLSAQTLTPYFTEMSSVAWGQPTGKL
LREKIGEIGRDAESAMLLATRQVNTHRGAIWALGLISAAAAQNNRQSDAVSLCARAGAIARLNDKYIPITFSKGKSACQR
YQVTGAKEEAQQGFPSIIKLALPTLRASRAKGDSEQAARLNALLVLMANINDTCVLSRGGENALLTVQHFCQEIIDGGGV
AAENGMSQLLKLGEIMIEGNLSPGGAADLLSATLFIDALENKLISRFHYATN

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=271, Percent_Identity=36.5313653136531, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 31301; Mature: 31301

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLLIDNDATWTCLKIAQLAQWALQEEVLLTPKPGLVDAADNGAHRDLSLELMLLSAQT
CCCEEECCCCCHHHHHHHHHHHHHHHCCEEECCCCCCEECCCCCCCCCEEEEEEEEEHHH
LTPYFTEMSSVAWGQPTGKLLREKIGEIGRDAESAMLLATRQVNTHRGAIWALGLISAAA
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHEEHHHHCCCCCCHHHHHHHHHHHH
AQNNRQSDAVSLCARAGAIARLNDKYIPITFSKGKSACQRYQVTGAKEEAQQGFPSIIKL
HCCCCHHHHHHHHHHCCCCEEECCCEEEEEECCCHHHHHHHHCCCCHHHHHCCCHHHHHH
ALPTLRASRAKGDSEQAARLNALLVLMANINDTCVLSRGGENALLTVQHFCQEIIDGGGV
HHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCEEEEECCCCCEEEEHHHHHHHHHCCCCC
AAENGMSQLLKLGEIMIEGNLSPGGAADLLSATLFIDALENKLISRFHYATN
CHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDNLLIDNDATWTCLKIAQLAQWALQEEVLLTPKPGLVDAADNGAHRDLSLELMLLSAQT
CCCEEECCCCCHHHHHHHHHHHHHHHCCEEECCCCCCEECCCCCCCCCEEEEEEEEEHHH
LTPYFTEMSSVAWGQPTGKLLREKIGEIGRDAESAMLLATRQVNTHRGAIWALGLISAAA
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHEEHHHHCCCCCCHHHHHHHHHHHH
AQNNRQSDAVSLCARAGAIARLNDKYIPITFSKGKSACQRYQVTGAKEEAQQGFPSIIKL
HCCCCHHHHHHHHHHCCCCEEECCCEEEEEECCCHHHHHHHHCCCCHHHHHCCCHHHHHH
ALPTLRASRAKGDSEQAARLNALLVLMANINDTCVLSRGGENALLTVQHFCQEIIDGGGV
HHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCEEEEECCCCCEEEEHHHHHHHHHCCCCC
AAENGMSQLLKLGEIMIEGNLSPGGAADLLSATLFIDALENKLISRFHYATN
CHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9208947; 11052675 [H]