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The map label for this gene is cysH [H]

Identifier: 119947039

GI number: 119947039

Start: 4248402

End: 4249166

Strand: Direct

Name: cysH [H]

Synonym: Ping_3436

Alternate gene names: 119947039

Gene position: 4248402-4249166 (Clockwise)

Preceding gene: 119947038

Following gene: 119947068

Centisome position: 93.17

GC content: 42.75

Gene sequence:

>765_bases
ATGACTAACAGATTGAATCTAACCCAGCTACTTAGTTTAGATAAAGCGCAACAGACTGAAGCCTTACAAGAAGCCAATGA
CCTGCTTGAAAATAAAACCGCCCGTGAACGCGTTGAATGGGCGATTGAACACCTTGAAAGTGAATTTGTTTTATCGTCAA
GTTTTGGCATTCAGGCAGCTGTCTGCCTGCATTTAATTACTCAGGTAAAAGCGGATACGCCGATTATTTTAACAGATACG
GGTTATCTGTTTCCGGAGACCTATCGGTTTATTGATGCGTTAACTGAAAAATTAAATCTGAACTTGAAAACGTATCGTGC
CGAGCACAGCAGTGCCTGGCAGGAAGCACGCTATGGTAAATTATGGGAGCAGGGTGTTGATGGCTTAACTCAGTACAACT
TAATCAATAAAGTTGAACCAATGAAACGCGCGCTTAAGGATCTTAATGCAAAAACCTGGTTTTCGGGTTTACGCCGCTCG
CAAGCATCCAGTCGTGGAAAACTGCCTGTATTAAGTATTCAAAATGGTTGTTTTAAGTTTTTACCTATTATTGATTGGAG
TAATAAAGACGTTCATTACTATCTCAGCGATCATGGTCTTGAGTACCACCCTCTTTGGGAGCAAGGTTATGTTTCGGTGG
GCGATGTGCAAACGTCTCAACCTCTGGGAGCTGGCATGAGCGAAGAAGAAACACGCTTCTTTGGTTTGAAACGCGAATGC
GGACTGCATGAAGATGATGTAGAAGAGCAAGGAAGTGGGATTTAG

Upstream 100 bases:

>100_bases
GGTCGTTGGGCAAATGAGCGTGAAAGCGGTGAATGTTTTGGTGATTTTGTTATCCGCGCTGCTATCATAGCTGAAGTTAT
TATCGCTTCTAAGGATTTTC

Downstream 100 bases:

>100_bases
AAAACAGGAAGGCTTGAAGGCTGTCAGCTGTCAGCCGAAAGCCATCAGCTCGAAGCGTTACCGCCATAACACAACATTTT
AAAACGCCTTAACTGGCGTT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTNRLNLTQLLSLDKAQQTEALQEANDLLENKTARERVEWAIEHLESEFVLSSSFGIQAAVCLHLITQVKADTPIILTDT
GYLFPETYRFIDALTEKLNLNLKTYRAEHSSAWQEARYGKLWEQGVDGLTQYNLINKVEPMKRALKDLNAKTWFSGLRRS
QASSRGKLPVLSIQNGCFKFLPIIDWSNKDVHYYLSDHGLEYHPLWEQGYVSVGDVQTSQPLGAGMSEEETRFFGLKREC
GLHEDDVEEQGSGI

Sequences:

>Translated_254_residues
MTNRLNLTQLLSLDKAQQTEALQEANDLLENKTARERVEWAIEHLESEFVLSSSFGIQAAVCLHLITQVKADTPIILTDT
GYLFPETYRFIDALTEKLNLNLKTYRAEHSSAWQEARYGKLWEQGVDGLTQYNLINKVEPMKRALKDLNAKTWFSGLRRS
QASSRGKLPVLSIQNGCFKFLPIIDWSNKDVHYYLSDHGLEYHPLWEQGYVSVGDVQTSQPLGAGMSEEETRFFGLKREC
GLHEDDVEEQGSGI
>Mature_253_residues
TNRLNLTQLLSLDKAQQTEALQEANDLLENKTARERVEWAIEHLESEFVLSSSFGIQAAVCLHLITQVKADTPIILTDTG
YLFPETYRFIDALTEKLNLNLKTYRAEHSSAWQEARYGKLWEQGVDGLTQYNLINKVEPMKRALKDLNAKTWFSGLRRSQ
ASSRGKLPVLSIQNGCFKFLPIIDWSNKDVHYYLSDHGLEYHPLWEQGYVSVGDVQTSQPLGAGMSEEETRFFGLKRECG
LHEDDVEEQGSGI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=242, Percent_Identity=65.702479338843, Blast_Score=340, Evalue=4e-95,
Organism=Saccharomyces cerevisiae, GI6325425, Length=230, Percent_Identity=31.304347826087, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 28943; Mature: 28812

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRLNLTQLLSLDKAQQTEALQEANDLLENKTARERVEWAIEHLESEFVLSSSFGIQAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHEECCCCCHHHH
VCLHLITQVKADTPIILTDTGYLFPETYRFIDALTEKLNLNLKTYRAEHSSAWQEARYGK
HHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHEEECHHHHHHHHHHHHH
LWEQGVDGLTQYNLINKVEPMKRALKDLNAKTWFSGLRRSQASSRGKLPVLSIQNGCFKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEE
LPIIDWSNKDVHYYLSDHGLEYHPLWEQGYVSVGDVQTSQPLGAGMSEEETRFFGLKREC
EEEEECCCCCEEEEECCCCCEECCCHHCCCEEECCCCCCCCCCCCCCCHHHHHHCCHHHC
GLHEDDVEEQGSGI
CCCCCCHHHCCCCC
>Mature Secondary Structure 
TNRLNLTQLLSLDKAQQTEALQEANDLLENKTARERVEWAIEHLESEFVLSSSFGIQAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHEECCCCCHHHH
VCLHLITQVKADTPIILTDTGYLFPETYRFIDALTEKLNLNLKTYRAEHSSAWQEARYGK
HHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHEEECHHHHHHHHHHHHH
LWEQGVDGLTQYNLINKVEPMKRALKDLNAKTWFSGLRRSQASSRGKLPVLSIQNGCFKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEE
LPIIDWSNKDVHYYLSDHGLEYHPLWEQGYVSVGDVQTSQPLGAGMSEEETRFFGLKREC
EEEEECCCCCEEEEECCCCCEECCCHHCCCEEECCCCCCCCCCCCCCCHHHHHHCCHHHC
GLHEDDVEEQGSGI
CCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA