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The map label for this gene is ilvH [H]

Identifier: 119947034

GI number: 119947034

Start: 4242791

End: 4243291

Strand: Direct

Name: ilvH [H]

Synonym: Ping_3431

Alternate gene names: 119947034

Gene position: 4242791-4243291 (Clockwise)

Preceding gene: 119947033

Following gene: 119947035

Centisome position: 93.05

GC content: 37.92

Gene sequence:

>501_bases
ATGCGTAGTATTATTTCAGTATTATTAGAAAATGAACCAGGTTCGCTTGCTCGTGTTGTTGGCTTATTTGCACAACGCGC
ATATAACATCGAGTCATTAACCGTTTCACCAACTAACGATTTAACATTATCAAGAATGACGATTACAACTGAAGTTGATT
GTAAAGCGACACTTGAGCAAATGATGAAGCAATTACACAAGTTAGTTGACGTGTTACGTGTTTCTGAATTAACAGAAGGT
CCACATGTTGAACGTGAATTACTATTAATCAAAGTACGTACTTCTAACAATGAAGATCGTGAAGAAGTAAAACGTACCTG
TGATATTTACCGAGGTCAAATAGTAGACATCACTCAGCATCTTTACACCATTCAATTAACAGGGGCAGGCGTTAAGTTAG
ATGCGTTTCTTGATACGATTAATAATGCAAGTGAAATTGTTGAAGTTGTCCGCTCAGGCGTCTGTGGTATTGCGCGTGGT
GAAAAAGCATTACGCGGTTAA

Upstream 100 bases:

>100_bases
TTTATTGATGTAGCTATAGACCCTGAAGAACATGTTTACCCGATGCAAGTTAAGTTCGGCAGTATGCAAGACATGTACCT
GAGTCAAACGGAGAGAACCG

Downstream 100 bases:

>100_bases
TTTCTGACTAAATGACCAGATGACCATCAATGCAAAGTTCAGGAATCTGGCTTTGCATTTTTTCTAAATAAATAAGGCGT
TTTATGTTCGAGCTCGGCGC

Product: acetolactate synthase, small subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MRSIISVLLENEPGSLARVVGLFAQRAYNIESLTVSPTNDLTLSRMTITTEVDCKATLEQMMKQLHKLVDVLRVSELTEG
PHVERELLLIKVRTSNNEDREEVKRTCDIYRGQIVDITQHLYTIQLTGAGVKLDAFLDTINNASEIVEVVRSGVCGIARG
EKALRG

Sequences:

>Translated_166_residues
MRSIISVLLENEPGSLARVVGLFAQRAYNIESLTVSPTNDLTLSRMTITTEVDCKATLEQMMKQLHKLVDVLRVSELTEG
PHVERELLLIKVRTSNNEDREEVKRTCDIYRGQIVDITQHLYTIQLTGAGVKLDAFLDTINNASEIVEVVRSGVCGIARG
EKALRG
>Mature_166_residues
MRSIISVLLENEPGSLARVVGLFAQRAYNIESLTVSPTNDLTLSRMTITTEVDCKATLEQMMKQLHKLVDVLRVSELTEG
PHVERELLLIKVRTSNNEDREEVKRTCDIYRGQIVDITQHLYTIQLTGAGVKLDAFLDTINNASEIVEVVRSGVCGIARG
EKALRG

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=165, Percent_Identity=63.6363636363636, Blast_Score=209, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=26.9607843137255, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18495; Mature: 18495

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIISVLLENEPGSLARVVGLFAQRAYNIESLTVSPTNDLTLSRMTITTEVDCKATLEQ
CHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEECCCHHHHHHH
MMKQLHKLVDVLRVSELTEGPHVERELLLIKVRTSNNEDREEVKRTCDIYRGQIVDITQH
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCHHEEEECC
LYTIQLTGAGVKLDAFLDTINNASEIVEVVRSGVCGIARGEKALRG
EEEEEECCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHCC
>Mature Secondary Structure
MRSIISVLLENEPGSLARVVGLFAQRAYNIESLTVSPTNDLTLSRMTITTEVDCKATLEQ
CHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEECCCHHHHHHH
MMKQLHKLVDVLRVSELTEGPHVERELLLIKVRTSNNEDREEVKRTCDIYRGQIVDITQH
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCHHEEEECC
LYTIQLTGAGVKLDAFLDTINNASEIVEVVRSGVCGIARGEKALRG
EEEEEECCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]