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The map label for this gene is yqjI [H]

Identifier: 119946558

GI number: 119946558

Start: 3621045

End: 3622547

Strand: Direct

Name: yqjI [H]

Synonym: Ping_2937

Alternate gene names: 119946558

Gene position: 3621045-3622547 (Clockwise)

Preceding gene: 119946557

Following gene: 119946567

Centisome position: 79.42

GC content: 47.31

Gene sequence:

>1503_bases
ATGAAGACTAAAATAGATATTGCCGTGATAGGCTTAGGCGTGATGGGTGCCAATATGGCACTAAATTTAGCAGAGCGGAG
ATTTTCAATAGCCGCTTTCGACACTAATGAGGCTCGCCGTCTCGACACCGCTAAACGCCACCAAGCGTTATCGGCTGCAG
CACTCACCACTGTTGCTTCTCTTTCTGAGTTAATCGACCAACTTGCTACACCGCGCTGCATCATACTCTCGGTTCCTGCG
GGCTCTATTGTGGATATTATTTGTCGGGACTTGCTGGCAGCAGGTTTACAGCAAGATGATATTGTTGTCGATACGGGCAA
CAGCCAATGGCGCGACTCGATTGATCGGGCGCAAACATACGCAGGTAAATTTAACTTCTTTACCTGCGCCATTTCCGGCG
GAGAAATGGGTGCACGTTTTGGACCTTCATTAATGCCCAGTGGTGACAAAAAAGTATGGCAGCAGTTAAAACCTATCTGG
CAGGCAATGGCAGCAAAAGTCAATCCCGTTACCGGTACAGAAATTGTGCGCAGCCAAGTAGAGCACCCCTTACCAGAAGG
CGAACCTTGTGCTGAGTATATTGGCCCGATTGGCTCCGGTCATTTTGTAAAAATGGTGCATAACGGTATTGAATATGCAG
ACATGCAGATGATTGCCGAAATAGTACAATTTATGCGTCAAATATTGACCATGTCGGCAGTGGAAGTCGGTGCGGTATTT
CGCCGCTGGAATAAAGGAAAACTGCAAAGTTATCTGATTGAAATTACGGCTGACATTCTTCTAACGGTCGATCCTAAAAC
AGGCCAGCCACTGGTCGATGTGATTATGGATCAGGCCAGTCAAAAAGGCACAGGAAACTGGACTGCACGTGAAGCATTAG
TACTCGGCGTACCGGCAACGGCCATTACCGCCTCGGTATTTGCTCGCTGCCTGAGTACTCAAAAAACGATTCGTCAAATC
GCTGCAGTGCAGTTAACCGGTCCTATTATCAGCACTGACGATAAAACCTTATGGATTGATAAACTGGCAGATGCGCTGTA
CTGCTCAAAAATCTGTAGCTATGCGCAGGGGTTCGAGCTGATGTCTGCTGCTGAAAAAGAGCATAATTGGACGCTTGATT
ATATTTCAATCGCTAAAATATGGCGTGGCGGTTGTGTGATACGCGCTCACTTTTTAGATGATATTTCCAAGGCCTATCAA
ACTGAGCCTGAATTACTTAATTTAATGCTGGCGGAAAGGTTCACAGACAGCCTGGCGAAAGGTCAGTTATCCTGGCGGGA
AGTCTTAGCCAAAGCGATTATGCAGGGGATGCCAATGCCCGCTATCAGCGCTGCGATCAGCTACTACGATTGCTACCGTG
AAGCTGATTCCTCTGCCAGCCTGATTCAGGCAATGCGTGATTATTTTGGCGGCCATACGTACCTGCGTAAAGATCGGGAT
TCAAGACAAAGTTTCCATTATGATTGGCACTTTGGTAGTGGTGAACAAACGGCTGAGCATTAA

Upstream 100 bases:

>100_bases
CGTCAAAATGTGAGTGAAATTGTAGCGGATATTATTCAAAAACTAAGTGATTTAAACAATAAATAAAATTTTCCTAATCT
ATCGAAACACTGAGAGCCGA

Downstream 100 bases:

>100_bases
TATCAAATCCACTGATTTTCTATCCATTTATCCCGGTTAAAATGAATAGAAAAAAGTGGATATTAGTAACGTTTTGCCGA
TAAAACATGACAGTCCGAGT

Product: 6-phosphogluconate dehydrogenase, decarboxylating

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MKTKIDIAVIGLGVMGANMALNLAERRFSIAAFDTNEARRLDTAKRHQALSAAALTTVASLSELIDQLATPRCIILSVPA
GSIVDIICRDLLAAGLQQDDIVVDTGNSQWRDSIDRAQTYAGKFNFFTCAISGGEMGARFGPSLMPSGDKKVWQQLKPIW
QAMAAKVNPVTGTEIVRSQVEHPLPEGEPCAEYIGPIGSGHFVKMVHNGIEYADMQMIAEIVQFMRQILTMSAVEVGAVF
RRWNKGKLQSYLIEITADILLTVDPKTGQPLVDVIMDQASQKGTGNWTAREALVLGVPATAITASVFARCLSTQKTIRQI
AAVQLTGPIISTDDKTLWIDKLADALYCSKICSYAQGFELMSAAEKEHNWTLDYISIAKIWRGGCVIRAHFLDDISKAYQ
TEPELLNLMLAERFTDSLAKGQLSWREVLAKAIMQGMPMPAISAAISYYDCYREADSSASLIQAMRDYFGGHTYLRKDRD
SRQSFHYDWHFGSGEQTAEH

Sequences:

>Translated_500_residues
MKTKIDIAVIGLGVMGANMALNLAERRFSIAAFDTNEARRLDTAKRHQALSAAALTTVASLSELIDQLATPRCIILSVPA
GSIVDIICRDLLAAGLQQDDIVVDTGNSQWRDSIDRAQTYAGKFNFFTCAISGGEMGARFGPSLMPSGDKKVWQQLKPIW
QAMAAKVNPVTGTEIVRSQVEHPLPEGEPCAEYIGPIGSGHFVKMVHNGIEYADMQMIAEIVQFMRQILTMSAVEVGAVF
RRWNKGKLQSYLIEITADILLTVDPKTGQPLVDVIMDQASQKGTGNWTAREALVLGVPATAITASVFARCLSTQKTIRQI
AAVQLTGPIISTDDKTLWIDKLADALYCSKICSYAQGFELMSAAEKEHNWTLDYISIAKIWRGGCVIRAHFLDDISKAYQ
TEPELLNLMLAERFTDSLAKGQLSWREVLAKAIMQGMPMPAISAAISYYDCYREADSSASLIQAMRDYFGGHTYLRKDRD
SRQSFHYDWHFGSGEQTAEH
>Mature_500_residues
MKTKIDIAVIGLGVMGANMALNLAERRFSIAAFDTNEARRLDTAKRHQALSAAALTTVASLSELIDQLATPRCIILSVPA
GSIVDIICRDLLAAGLQQDDIVVDTGNSQWRDSIDRAQTYAGKFNFFTCAISGGEMGARFGPSLMPSGDKKVWQQLKPIW
QAMAAKVNPVTGTEIVRSQVEHPLPEGEPCAEYIGPIGSGHFVKMVHNGIEYADMQMIAEIVQFMRQILTMSAVEVGAVF
RRWNKGKLQSYLIEITADILLTVDPKTGQPLVDVIMDQASQKGTGNWTAREALVLGVPATAITASVFARCLSTQKTIRQI
AAVQLTGPIISTDDKTLWIDKLADALYCSKICSYAQGFELMSAAEKEHNWTLDYISIAKIWRGGCVIRAHFLDDISKAYQ
TEPELLNLMLAERFTDSLAKGQLSWREVLAKAIMQGMPMPAISAAISYYDCYREADSSASLIQAMRDYFGGHTYLRKDRD
SRQSFHYDWHFGSGEQTAEH

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=487, Percent_Identity=44.5585215605749, Blast_Score=374, Evalue=1e-103,
Organism=Escherichia coli, GI1788341, Length=489, Percent_Identity=42.7402862985685, Blast_Score=391, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17542558, Length=474, Percent_Identity=44.7257383966245, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321695, Length=473, Percent_Identity=43.7632135306554, Blast_Score=395, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6321977, Length=473, Percent_Identity=43.5517970401691, Blast_Score=377, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24639279, Length=503, Percent_Identity=43.7375745526839, Blast_Score=375, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 55133; Mature: 55133

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00895 3_HYDROXYISOBUT_DH ; PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKIDIAVIGLGVMGANMALNLAERRFSIAAFDTNEARRLDTAKRHQALSAAALTTVAS
CCCEEEEEEEEHHHHCCHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LSELIDQLATPRCIILSVPAGSIVDIICRDLLAAGLQQDDIVVDTGNSQWRDSIDRAQTY
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHH
AGKFNFFTCAISGGEMGARFGPSLMPSGDKKVWQQLKPIWQAMAAKVNPVTGTEIVRSQV
CCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EHPLPEGEPCAEYIGPIGSGHFVKMVHNGIEYADMQMIAEIVQFMRQILTMSAVEVGAVF
HCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRWNKGKLQSYLIEITADILLTVDPKTGQPLVDVIMDQASQKGTGNWTAREALVLGVPAT
HHCCCHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHCEEEEECCHH
AITASVFARCLSTQKTIRQIAAVQLTGPIISTDDKTLWIDKLADALYCSKICSYAQGFEL
HHHHHHHHHHHHHHHHHHHHHHHHEECCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHH
MSAAEKEHNWTLDYISIAKIWRGGCVIRAHFLDDISKAYQTEPELLNLMLAERFTDSLAK
HHHHHHCCCCEEHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GQLSWREVLAKAIMQGMPMPAISAAISYYDCYREADSSASLIQAMRDYFGGHTYLRKDRD
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCC
SRQSFHYDWHFGSGEQTAEH
CCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKTKIDIAVIGLGVMGANMALNLAERRFSIAAFDTNEARRLDTAKRHQALSAAALTTVAS
CCCEEEEEEEEHHHHCCHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LSELIDQLATPRCIILSVPAGSIVDIICRDLLAAGLQQDDIVVDTGNSQWRDSIDRAQTY
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHH
AGKFNFFTCAISGGEMGARFGPSLMPSGDKKVWQQLKPIWQAMAAKVNPVTGTEIVRSQV
CCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EHPLPEGEPCAEYIGPIGSGHFVKMVHNGIEYADMQMIAEIVQFMRQILTMSAVEVGAVF
HCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRWNKGKLQSYLIEITADILLTVDPKTGQPLVDVIMDQASQKGTGNWTAREALVLGVPAT
HHCCCHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHCEEEEECCHH
AITASVFARCLSTQKTIRQIAAVQLTGPIISTDDKTLWIDKLADALYCSKICSYAQGFEL
HHHHHHHHHHHHHHHHHHHHHHHHEECCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHH
MSAAEKEHNWTLDYISIAKIWRGGCVIRAHFLDDISKAYQTEPELLNLMLAERFTDSLAK
HHHHHHCCCCEEHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GQLSWREVLAKAIMQGMPMPAISAAISYYDCYREADSSASLIQAMRDYFGGHTYLRKDRD
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCC
SRQSFHYDWHFGSGEQTAEH
CCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]