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The map label for this gene is phnW

Identifier: 119946373

GI number: 119946373

Start: 3370205

End: 3371311

Strand: Direct

Name: phnW

Synonym: Ping_2747

Alternate gene names: 119946373

Gene position: 3370205-3371311 (Clockwise)

Preceding gene: 119946367

Following gene: 119946374

Centisome position: 73.91

GC content: 41.92

Gene sequence:

>1107_bases
ATGAACAATGAATATTTACTACTGACCCCCGGGCCGTTATCAACCTCTAAAACAGTGCGTAATGCCATGCTTAAAGATTG
GTGTACTTGGGATGATCAATATAATAAAGAAATTGTTGAGGTGATTAGGGATAAACTGGTAAAGCTTGCCACCACACAAA
AAAACTATACCTGCGTTTTAATGCAGGGCTCGGGCACGGCGTCCGTTGAAGCGACCATCGGCAGTGTTATCGACAAACAA
GGCAAATTATTAGTCATTGATAATGGCTCCTATGGTGCGAGAATGGCCGAAATTGCGCACTATCTTGCGCTTGACTGTGT
TGTGCTTGCACCCGGTGAAACAACTCAGCCTGATTTACAACTGCTTGAAAGCACGCTGCTTAATGACCCGAAGATTACTC
ATGTTGCTATGGTGCACTGCGAAACCACCACGGGAATGTTAAATCCCCTTGAAGATTTTTGTCGCATTGCTAAAGCCCAT
AACAAAGTCACTATTGTCGATGCTATGTCCAGTTTTGGTGGCATTGAGATGGATATTGGGCAATTGAATATCGACTTTAT
GATTAGCTCTGCCAATAAATGCATTCAAGGTGTGCCCGGGTTTGCTTTTGTGATTGCTAAACAGAGTGTTTTGCAGGAAT
GCAAAGGGTTAGCCCGTTCACTGACCTTAGATTTATATGCTCAGTGGCAATGTATGCAGGAAAATAATGGTAAATGGCGA
TTCACCTCACCCACTCATACGGTACGTGCATTTTATCAGGCCTTGCTGGAATTAGAAGAAGAAGGCGGCATTGGAGAGCG
TCAACAACGTTATATCACTAACCAAAAAAAATTAGTAACAGGCATGCGTGAATTAGGTTTTAAAACACTTTTACCCGATG
CTCTACATTCGCCGATTATCACTTCATTCCATTCTCCAAGCTCACCTGAATATGACTTCAAACGTTTCTATGTGTTATTA
AAAGCAGCAGGTTTTGTGATTTATCCGGGCAAAGTATCCAATGCCGATTGTTTCCGTATTGGCAATATTGGCGAGGTTTA
TCCTGAAGATATTGATAAGCTAATGATTGCCATAAAAAATGTTATTTACTGGCAAGTCGCTGCATGA

Upstream 100 bases:

>100_bases
TTTGTGAAACTTGCTGTCTCACTCTTTACCAGGGTATTTTTTAGTATTAAAGTAATAGACAATTCTGGTCTACACCAAAA
ACCAAATAAAAAGAGGCATT

Downstream 100 bases:

>100_bases
ATAAAGTCATGCCTGATAAGGCACATCTGCGCAGTGAAGGTGATCTAAATACCACAAAAGCCAGGCAAGACTGGCAACAT
AAACAGCAGCATCAACAGAC

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MNNEYLLLTPGPLSTSKTVRNAMLKDWCTWDDQYNKEIVEVIRDKLVKLATTQKNYTCVLMQGSGTASVEATIGSVIDKQ
GKLLVIDNGSYGARMAEIAHYLALDCVVLAPGETTQPDLQLLESTLLNDPKITHVAMVHCETTTGMLNPLEDFCRIAKAH
NKVTIVDAMSSFGGIEMDIGQLNIDFMISSANKCIQGVPGFAFVIAKQSVLQECKGLARSLTLDLYAQWQCMQENNGKWR
FTSPTHTVRAFYQALLELEEEGGIGERQQRYITNQKKLVTGMRELGFKTLLPDALHSPIITSFHSPSSPEYDFKRFYVLL
KAAGFVIYPGKVSNADCFRIGNIGEVYPEDIDKLMIAIKNVIYWQVAA

Sequences:

>Translated_368_residues
MNNEYLLLTPGPLSTSKTVRNAMLKDWCTWDDQYNKEIVEVIRDKLVKLATTQKNYTCVLMQGSGTASVEATIGSVIDKQ
GKLLVIDNGSYGARMAEIAHYLALDCVVLAPGETTQPDLQLLESTLLNDPKITHVAMVHCETTTGMLNPLEDFCRIAKAH
NKVTIVDAMSSFGGIEMDIGQLNIDFMISSANKCIQGVPGFAFVIAKQSVLQECKGLARSLTLDLYAQWQCMQENNGKWR
FTSPTHTVRAFYQALLELEEEGGIGERQQRYITNQKKLVTGMRELGFKTLLPDALHSPIITSFHSPSSPEYDFKRFYVLL
KAAGFVIYPGKVSNADCFRIGNIGEVYPEDIDKLMIAIKNVIYWQVAA
>Mature_368_residues
MNNEYLLLTPGPLSTSKTVRNAMLKDWCTWDDQYNKEIVEVIRDKLVKLATTQKNYTCVLMQGSGTASVEATIGSVIDKQ
GKLLVIDNGSYGARMAEIAHYLALDCVVLAPGETTQPDLQLLESTLLNDPKITHVAMVHCETTTGMLNPLEDFCRIAKAH
NKVTIVDAMSSFGGIEMDIGQLNIDFMISSANKCIQGVPGFAFVIAKQSVLQECKGLARSLTLDLYAQWQCMQENNGKWR
FTSPTHTVRAFYQALLELEEEGGIGERQQRYITNQKKLVTGMRELGFKTLLPDALHSPIITSFHSPSSPEYDFKRFYVLL
KAAGFVIYPGKVSNADCFRIGNIGEVYPEDIDKLMIAIKNVIYWQVAA

Specific function: Involved in phosphonate degradation

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily

Homologues:

Organism=Homo sapiens, GI4557289, Length=366, Percent_Identity=21.5846994535519, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17536281, Length=350, Percent_Identity=22.8571428571429, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNW_PSYIN (A1SY89)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944053.1
- ProteinModelPortal:   A1SY89
- SMR:   A1SY89
- STRING:   A1SY89
- GeneID:   4626008
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2747
- eggNOG:   COG0075
- HOGENOM:   HBG423997
- OMA:   HSLAMDL
- ProtClustDB:   PRK13479
- BioCyc:   PING357804:PING_2747-MONOMER
- HAMAP:   MF_01376
- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03301
- TIGRFAMs:   TIGR02326

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.37

Molecular weight: Translated: 40995; Mature: 40995

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNEYLLLTPGPLSTSKTVRNAMLKDWCTWDDQYNKEIVEVIRDKLVKLATTQKNYTCVL
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCCCEEEEE
MQGSGTASVEATIGSVIDKQGKLLVIDNGSYGARMAEIAHYLALDCVVLAPGETTQPDLQ
EECCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHH
LLESTLLNDPKITHVAMVHCETTTGMLNPLEDFCRIAKAHNKVTIVDAMSSFGGIEMDIG
HHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCEEEEC
QLNIDFMISSANKCIQGVPGFAFVIAKQSVLQECKGLARSLTLDLYAQWQCMQENNGKWR
EEEEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEE
FTSPTHTVRAFYQALLELEEEGGIGERQQRYITNQKKLVTGMRELGFKTLLPDALHSPII
ECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCHH
TSFHSPSSPEYDFKRFYVLLKAAGFVIYPGKVSNADCFRIGNIGEVYPEDIDKLMIAIKN
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHH
VIYWQVAA
HHEEEEEC
>Mature Secondary Structure
MNNEYLLLTPGPLSTSKTVRNAMLKDWCTWDDQYNKEIVEVIRDKLVKLATTQKNYTCVL
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCCCEEEEE
MQGSGTASVEATIGSVIDKQGKLLVIDNGSYGARMAEIAHYLALDCVVLAPGETTQPDLQ
EECCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHH
LLESTLLNDPKITHVAMVHCETTTGMLNPLEDFCRIAKAHNKVTIVDAMSSFGGIEMDIG
HHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCEEEEC
QLNIDFMISSANKCIQGVPGFAFVIAKQSVLQECKGLARSLTLDLYAQWQCMQENNGKWR
EEEEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEE
FTSPTHTVRAFYQALLELEEEGGIGERQQRYITNQKKLVTGMRELGFKTLLPDALHSPII
ECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCHH
TSFHSPSSPEYDFKRFYVLLKAAGFVIYPGKVSNADCFRIGNIGEVYPEDIDKLMIAIKN
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHH
VIYWQVAA
HHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA