Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 119946359

GI number: 119946359

Start: 3350274

End: 3352049

Strand: Reverse

Name: yciR [C]

Synonym: Ping_2730

Alternate gene names: 119946359

Gene position: 3352049-3350274 (Counterclockwise)

Preceding gene: 119946361

Following gene: 119946356

Centisome position: 73.52

GC content: 45.95

Gene sequence:

>1776_bases
ATGAGTAAGGACGCAGAATACGACAGTAAAATTAATGACAGGAAAGGCTATTTGTCAGAGCTTGCTATTGCCAACAATAA
GCTGGCCGTTGCCAACAGTGCGCTGGCGATTGCCAACAAGAAGCTTACCATTGCCAACAAGAAGCTTACCATTGCCAACA
AGAAGCTTACCATTGCCAACAAGGAGCTTGCCATTGTCAACGAGGAGCTTGCCATTGCCAACAAGGAGCTTGCCTTTCAA
AACGAAGAGAAGGATAAACGGGCAGCGGAGCTTGCTATTGCCAACCAGGAGCTTACCTTTCAAAACAAAGAGAAAGCTAA
ACGGGCAGTGGAGCTTGCTATTGCCAATAAAGAACTTGCCTTTCAAAGCAAAGAGAAAGCTAAACGGGCAGCGGAGCTTG
CTATTGTCAACCAGGATCTTACCTTTCAAAGCAAAGAGAAAGCTAAACTGGCAGAAGAGCTTAATGACCTTGCCTTCTAT
GACACGCTTACCGGCTTGCCCAACAGGCGTCTTTTGATAGACCGGCTGCATCACGCATTAGCTTCCAACGTGCGTCAAGG
CTGTGAAAGTGCGGTGATGTTTATTGATTTGGATCATTTCAAGGATATCAACGACACCCTCGGCCATGAAGTCGGTGATT
TACTGCTGATACAGACAGCGCAACGCCTGGAATCCTGTCTACGCAAAGGCGATACCGTGGCGCGTCTGGGAGGGGATGAG
TTTATGTTGATTCTGGAAAACCTGGACGAAAATCCCATTGAAGCCGCAACAAAGGCGAAGGCTATTGCTGATAAAATTTT
AGCTGAGCTCAACAAACCTTACCAACTCGACATGCACAAATGTCACAGCACCGTAAGTATCGGTGCGGTCTTTTTCGACC
ATCAGGGTAATACGGCAGAAGATCTGATCAAACAAGCCGATATCGCCATGTATCAGGCCAAACAAGCAGGTGGCAATCTG
ATCAGGTTCTTTAACCCGAAAATGCAGGAGAGTATTAACGCGCGCATCACCCTCGAAAATGAATTGCGCATTGCCATTGA
AAAGTCGCAATTTCATTTGTATTACCAAATTCAGATGGACAGTGACAACCGGGTATTGGGAGCCGAAGCATTGATCCGCT
GGACGAACCCTGAACACGGGCTAGTGTTACCTGCTACCTTTATCCCTATAGCGGAAGAAACCGGATTGATTCTGTCCATT
GGGAAATGGGTTATCGAAACGGCTTGTGCGCAGATCAAAGTATGGCAGAAAAAGTCGCAGACGCGCGACTTAACACTGGC
AGTCAATGTGAGTGCAAAACAATTCCGGCAGAAGGATTTCGTGGATCAAGTCCAGTCAGCTGTACAACGACATGCTATTC
CCGGAAATTTACTCAAGCTGGAATTGACCGAAAGCCTGCTGCAATATGACACCGAAGTCACCATTGCCATGATGAAGGCA
TTAAATAAGATTGGCGTGCAGTTCTCTCTGGATGACTTTGGAACAGGTTATTCATCCTTACAGTACCTTAAGCGGCTGCC
CCTCGATCAGTTCAAAATCGACCAGTCCTTTGTGCGCGATATTGCGACAGATAATAACGATAAAGCGATAGTCAAAGCGA
TTATTGCTATGGCACAGATTCTGGATATAGACGTCATTGCCGAGGGAGTGGAAACTGAAGAGCAACAACAATTACTCTTA
GGAAAAGGTTGCACTCTTTACCAAGGATATTTATTCAGCAAACCAATACCTATTGATCAGTTTGATGCATTAATCGGTCG
TTTTACTGACAGCTAA

Upstream 100 bases:

>100_bases
AATAATTTTGGTTTTACAGTTGCCGTAAAGGGAAAGTGGGGGGATTATCAAATATCCTGCCCTTCCTAAGACACGGTTTA
AATGTAAGAGGGTTAAACAA

Downstream 100 bases:

>100_bases
TATTAAGCACTGAGGGTTAGTGCTGTTGGTATTATTGGTAGGGTGCATTCTATGCACTGCAAACAGTGTTAATGCACCCT
ACGAGCTGACCAAATAAGCC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 590

Protein sequence:

>591_residues
MSKDAEYDSKINDRKGYLSELAIANNKLAVANSALAIANKKLTIANKKLTIANKKLTIANKELAIVNEELAIANKELAFQ
NEEKDKRAAELAIANQELTFQNKEKAKRAVELAIANKELAFQSKEKAKRAAELAIVNQDLTFQSKEKAKLAEELNDLAFY
DTLTGLPNRRLLIDRLHHALASNVRQGCESAVMFIDLDHFKDINDTLGHEVGDLLLIQTAQRLESCLRKGDTVARLGGDE
FMLILENLDENPIEAATKAKAIADKILAELNKPYQLDMHKCHSTVSIGAVFFDHQGNTAEDLIKQADIAMYQAKQAGGNL
IRFFNPKMQESINARITLENELRIAIEKSQFHLYYQIQMDSDNRVLGAEALIRWTNPEHGLVLPATFIPIAEETGLILSI
GKWVIETACAQIKVWQKKSQTRDLTLAVNVSAKQFRQKDFVDQVQSAVQRHAIPGNLLKLELTESLLQYDTEVTIAMMKA
LNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKAIIAMAQILDIDVIAEGVETEEQQQLLL
GKGCTLYQGYLFSKPIPIDQFDALIGRFTDS

Sequences:

>Translated_591_residues
MSKDAEYDSKINDRKGYLSELAIANNKLAVANSALAIANKKLTIANKKLTIANKKLTIANKELAIVNEELAIANKELAFQ
NEEKDKRAAELAIANQELTFQNKEKAKRAVELAIANKELAFQSKEKAKRAAELAIVNQDLTFQSKEKAKLAEELNDLAFY
DTLTGLPNRRLLIDRLHHALASNVRQGCESAVMFIDLDHFKDINDTLGHEVGDLLLIQTAQRLESCLRKGDTVARLGGDE
FMLILENLDENPIEAATKAKAIADKILAELNKPYQLDMHKCHSTVSIGAVFFDHQGNTAEDLIKQADIAMYQAKQAGGNL
IRFFNPKMQESINARITLENELRIAIEKSQFHLYYQIQMDSDNRVLGAEALIRWTNPEHGLVLPATFIPIAEETGLILSI
GKWVIETACAQIKVWQKKSQTRDLTLAVNVSAKQFRQKDFVDQVQSAVQRHAIPGNLLKLELTESLLQYDTEVTIAMMKA
LNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKAIIAMAQILDIDVIAEGVETEEQQQLLL
GKGCTLYQGYLFSKPIPIDQFDALIGRFTDS
>Mature_590_residues
SKDAEYDSKINDRKGYLSELAIANNKLAVANSALAIANKKLTIANKKLTIANKKLTIANKELAIVNEELAIANKELAFQN
EEKDKRAAELAIANQELTFQNKEKAKRAVELAIANKELAFQSKEKAKRAAELAIVNQDLTFQSKEKAKLAEELNDLAFYD
TLTGLPNRRLLIDRLHHALASNVRQGCESAVMFIDLDHFKDINDTLGHEVGDLLLIQTAQRLESCLRKGDTVARLGGDEF
MLILENLDENPIEAATKAKAIADKILAELNKPYQLDMHKCHSTVSIGAVFFDHQGNTAEDLIKQADIAMYQAKQAGGNLI
RFFNPKMQESINARITLENELRIAIEKSQFHLYYQIQMDSDNRVLGAEALIRWTNPEHGLVLPATFIPIAEETGLILSIG
KWVIETACAQIKVWQKKSQTRDLTLAVNVSAKQFRQKDFVDQVQSAVQRHAIPGNLLKLELTESLLQYDTEVTIAMMKAL
NKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKAIIAMAQILDIDVIAEGVETEEQQQLLLG
KGCTLYQGYLFSKPIPIDQFDALIGRFTDS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=445, Percent_Identity=36.8539325842697, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI87081921, Length=457, Percent_Identity=35.8862144420131, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI226510982, Length=436, Percent_Identity=32.5688073394495, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1787055, Length=253, Percent_Identity=35.5731225296443, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=34.8, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786507, Length=267, Percent_Identity=33.7078651685393, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1790496, Length=247, Percent_Identity=34.0080971659919, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1788502, Length=253, Percent_Identity=31.6205533596838, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87081845, Length=253, Percent_Identity=33.9920948616601, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1788849, Length=452, Percent_Identity=26.9911504424779, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081743, Length=244, Percent_Identity=30.327868852459, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI87082096, Length=252, Percent_Identity=29.7619047619048, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788381, Length=451, Percent_Identity=25.4988913525499, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87081977, Length=202, Percent_Identity=32.6732673267327, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1786584, Length=216, Percent_Identity=31.0185185185185, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87081881, Length=190, Percent_Identity=36.3157894736842, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=35.7142857142857, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=33.5294117647059, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788956, Length=186, Percent_Identity=36.5591397849462, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=34.8837209302326, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787816, Length=221, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081974, Length=108, Percent_Identity=44.4444444444444, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788085, Length=169, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789650, Length=440, Percent_Identity=20.2272727272727, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=194, Percent_Identity=30.4123711340206, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787410, Length=138, Percent_Identity=29.7101449275362, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 66090; Mature: 65958

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDAEYDSKINDRKGYLSELAIANNKLAVANSALAIANKKLTIANKKLTIANKKLTIAN
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCEEEEECCEEEEECCEEEEECCEEEEEC
KELAIVNEELAIANKELAFQNEEKDKRAAELAIANQELTFQNKEKAKRAVELAIANKELA
CEEEEEEHHHHHCCHHHCCCCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCCCCHHH
FQSKEKAKRAAELAIVNQDLTFQSKEKAKLAEELNDLAFYDTLTGLPNRRLLIDRLHHAL
HCCHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ASNVRQGCESAVMFIDLDHFKDINDTLGHEVGDLLLIQTAQRLESCLRKGDTVARLGGDE
HHHHHHHHHHEEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCE
FMLILENLDENPIEAATKAKAIADKILAELNKPYQLDMHKCHSTVSIGAVFFDHQGNTAE
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEECHHHHCCCEEEEEEEEECCCCCHH
DLIKQADIAMYQAKQAGGNLIRFFNPKMQESINARITLENELRIAIEKSQFHLYYQIQMD
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCEEEEEECCEEEEEEECEEEEEEEEEEC
SDNRVLGAEALIRWTNPEHGLVLPATFIPIAEETGLILSIGKWVIETACAQIKVWQKKSQ
CCCCEECCCCEEEECCCCCCEEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCC
TRDLTLAVNVSAKQFRQKDFVDQVQSAVQRHAIPGNLLKLELTESLLQYDTEVTIAMMKA
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCHHHHHHHHH
LNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKAIIAMAQI
HHHCCCEEEEHHCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHH
LDIDVIAEGVETEEQQQLLLGKGCTLYQGYLFSKPIPIDQFDALIGRFTDS
HHHHHHHCCCCCHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKDAEYDSKINDRKGYLSELAIANNKLAVANSALAIANKKLTIANKKLTIANKKLTIAN
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCEEEEECCEEEEECCEEEEECCEEEEEC
KELAIVNEELAIANKELAFQNEEKDKRAAELAIANQELTFQNKEKAKRAVELAIANKELA
CEEEEEEHHHHHCCHHHCCCCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCCCCHHH
FQSKEKAKRAAELAIVNQDLTFQSKEKAKLAEELNDLAFYDTLTGLPNRRLLIDRLHHAL
HCCHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ASNVRQGCESAVMFIDLDHFKDINDTLGHEVGDLLLIQTAQRLESCLRKGDTVARLGGDE
HHHHHHHHHHEEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCE
FMLILENLDENPIEAATKAKAIADKILAELNKPYQLDMHKCHSTVSIGAVFFDHQGNTAE
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEECHHHHCCCEEEEEEEEECCCCCHH
DLIKQADIAMYQAKQAGGNLIRFFNPKMQESINARITLENELRIAIEKSQFHLYYQIQMD
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCEEEEEECCEEEEEEECEEEEEEEEEEC
SDNRVLGAEALIRWTNPEHGLVLPATFIPIAEETGLILSIGKWVIETACAQIKVWQKKSQ
CCCCEECCCCEEEECCCCCCEEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCC
TRDLTLAVNVSAKQFRQKDFVDQVQSAVQRHAIPGNLLKLELTESLLQYDTEVTIAMMKA
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCHHHHHHHHH
LNKIGVQFSLDDFGTGYSSLQYLKRLPLDQFKIDQSFVRDIATDNNDKAIVKAIIAMAQI
HHHCCCEEEEHHCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHH
LDIDVIAEGVETEEQQQLLLGKGCTLYQGYLFSKPIPIDQFDALIGRFTDS
HHHHHHHCCCCCHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]