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The map label for this gene is 119946326

Identifier: 119946326

GI number: 119946326

Start: 3308884

End: 3309807

Strand: Direct

Name: 119946326

Synonym: Ping_2697

Alternate gene names: NA

Gene position: 3308884-3309807 (Clockwise)

Preceding gene: 119946324

Following gene: 119946327

Centisome position: 72.57

GC content: 41.02

Gene sequence:

>924_bases
ATGACTGTTGGTATTATTAGTCATCACCGTTGTAGTCGCCATAATATGGGGGATCACCACCCGGAAAGCCCTCAAAGGAT
GGGGGCAATACAAGATCAGTTAATTAGAAGTGGCCTTGAATACGTTATTCACCAATATGATGCAACACCGATTGCCCGTG
AAATTATTGAACTTGCTCATGACAAGAAATATATAGACTACATTTTCGACAATGCCCCAAAAGAAGGGATGTTTCGCGTT
GATGATGATACATCAATGAACCCTGAATCGCTCCCCGCAGCTTTACTTTCTGCCGGAGCCGCAATTAATGCTGTTGATTT
AGTGATGGATAAAACACTTAGCGCCGTATTTTGTGCCACTCGCCCCCCCGGGCATCATGCAGAATATGATAAAGGAATGG
GATTTTGTTTCTTCAATAATATTGCAATTGCTGCCGCATACGCCAAAAAAAAGTATCAACTAGAACGAGTGGCCATTCTA
GACTTTGATGTGCATCACGGTAATGGCACAGAAAATATCGTTAAAAATAAAACTGGTTATTTATTTTGCTCAACCTACCA
ATACCCATTTTTCCCTTTTGAAATGCAGGAGAGTAATACCCCTCCCATCATTAACACCCCATTGCCAGCAACCACAAAAG
GTCCTGAATTTCGTCAAGCCATTACTGAAAACTGGTTACCTGCCTTGCATAAATTTAAACCACAATTAATTTTAATTTCA
GCAGGCTTTGATGCTCATATAGAAGATGAAATGTCGCAAATAAGTTTAACTGAAAGCGATTATCGTTGGGTAACTGACGA
AATAAAGATTATTGCCGATCAATACGCCGAAGGCCGGATTGTTTCCATGCTAGAGGGGGGCTATGCCTTAAATGCCCTAG
GGCGAAGTGTCGTTGAACATGTAAAAGGTTTGATTGGTAGTTAA

Upstream 100 bases:

>100_bases
TTATGGTTTATTCGGACCTATAGCGAGACTATGATGAACTTAGTTTAGCATTACCTTTAACGCCCCCTGGTGTTGAAGCA
CTAGGAAAGGAGGATATGAT

Downstream 100 bases:

>100_bases
TACTGTCGAACTAAATTAAAGCTAAATATAATGATATTCCCCTAGCCCGTGTCTCGTTATGAGGTTGGCTTGTCAAATCA
GATAAGGATTACATGCTTTC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTVGIISHHRCSRHNMGDHHPESPQRMGAIQDQLIRSGLEYVIHQYDATPIAREIIELAHDKKYIDYIFDNAPKEGMFRV
DDDTSMNPESLPAALLSAGAAINAVDLVMDKTLSAVFCATRPPGHHAEYDKGMGFCFFNNIAIAAAYAKKKYQLERVAIL
DFDVHHGNGTENIVKNKTGYLFCSTYQYPFFPFEMQESNTPPIINTPLPATTKGPEFRQAITENWLPALHKFKPQLILIS
AGFDAHIEDEMSQISLTESDYRWVTDEIKIIADQYAEGRIVSMLEGGYALNALGRSVVEHVKGLIGS

Sequences:

>Translated_307_residues
MTVGIISHHRCSRHNMGDHHPESPQRMGAIQDQLIRSGLEYVIHQYDATPIAREIIELAHDKKYIDYIFDNAPKEGMFRV
DDDTSMNPESLPAALLSAGAAINAVDLVMDKTLSAVFCATRPPGHHAEYDKGMGFCFFNNIAIAAAYAKKKYQLERVAIL
DFDVHHGNGTENIVKNKTGYLFCSTYQYPFFPFEMQESNTPPIINTPLPATTKGPEFRQAITENWLPALHKFKPQLILIS
AGFDAHIEDEMSQISLTESDYRWVTDEIKIIADQYAEGRIVSMLEGGYALNALGRSVVEHVKGLIGS
>Mature_306_residues
TVGIISHHRCSRHNMGDHHPESPQRMGAIQDQLIRSGLEYVIHQYDATPIAREIIELAHDKKYIDYIFDNAPKEGMFRVD
DDTSMNPESLPAALLSAGAAINAVDLVMDKTLSAVFCATRPPGHHAEYDKGMGFCFFNNIAIAAAYAKKKYQLERVAILD
FDVHHGNGTENIVKNKTGYLFCSTYQYPFFPFEMQESNTPPIINTPLPATTKGPEFRQAITENWLPALHKFKPQLILISA
GFDAHIEDEMSQISLTESDYRWVTDEIKIIADQYAEGRIVSMLEGGYALNALGRSVVEHVKGLIGS

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=303, Percent_Identity=32.3432343234323, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI13128864, Length=307, Percent_Identity=32.5732899022801, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI226529806, Length=303, Percent_Identity=29.3729372937294, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI30795204, Length=347, Percent_Identity=29.971181556196, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI30795202, Length=347, Percent_Identity=29.971181556196, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI17158039, Length=347, Percent_Identity=29.971181556196, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI62750349, Length=317, Percent_Identity=29.9684542586751, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI62750347, Length=317, Percent_Identity=29.9684542586751, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI153085395, Length=338, Percent_Identity=28.698224852071, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI169234807, Length=344, Percent_Identity=27.0348837209302, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI148539870, Length=344, Percent_Identity=27.0348837209302, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17540334, Length=300, Percent_Identity=31.6666666666667, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17540332, Length=300, Percent_Identity=31.6666666666667, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI193206283, Length=300, Percent_Identity=31.6666666666667, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI193209491, Length=337, Percent_Identity=30.8605341246291, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25154022, Length=296, Percent_Identity=31.4189189189189, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25154020, Length=294, Percent_Identity=31.2925170068027, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17537347, Length=322, Percent_Identity=31.055900621118, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17534739, Length=305, Percent_Identity=21.3114754098361, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=321, Percent_Identity=30.8411214953271, Blast_Score=133, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6325141, Length=288, Percent_Identity=26.3888888888889, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323999, Length=296, Percent_Identity=22.6351351351351, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360899, Length=316, Percent_Identity=33.8607594936709, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24642142, Length=316, Percent_Identity=33.8607594936709, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24642146, Length=316, Percent_Identity=33.8607594936709, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24642144, Length=316, Percent_Identity=33.8607594936709, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281360801, Length=253, Percent_Identity=32.8063241106719, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641720, Length=253, Percent_Identity=32.8063241106719, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281360799, Length=253, Percent_Identity=32.8063241106719, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34345; Mature: 34214

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGIISHHRCSRHNMGDHHPESPQRMGAIQDQLIRSGLEYVIHQYDATPIAREIIELAH
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
DKKYIDYIFDNAPKEGMFRVDDDTSMNPESLPAALLSAGAAINAVDLVMDKTLSAVFCAT
CCHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEC
RPPGHHAEYDKGMGFCFFNNIAIAAAYAKKKYQLERVAILDFDVHHGNGTENIVKNKTGY
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHEEEEEEEEEEEECCCCCHHHHCCCCCE
LFCSTYQYPFFPFEMQESNTPPIINTPLPATTKGPEFRQAITENWLPALHKFKPQLILIS
EEEEECCCCCCEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
AGFDAHIEDEMSQISLTESDYRWVTDEIKIIADQYAEGRIVSMLEGGYALNALGRSVVEH
CCCCCCHHHHHHHEECCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
VKGLIGS
HHHHHCC
>Mature Secondary Structure 
TVGIISHHRCSRHNMGDHHPESPQRMGAIQDQLIRSGLEYVIHQYDATPIAREIIELAH
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
DKKYIDYIFDNAPKEGMFRVDDDTSMNPESLPAALLSAGAAINAVDLVMDKTLSAVFCAT
CCHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEC
RPPGHHAEYDKGMGFCFFNNIAIAAAYAKKKYQLERVAILDFDVHHGNGTENIVKNKTGY
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHEEEEEEEEEEEECCCCCHHHHCCCCCE
LFCSTYQYPFFPFEMQESNTPPIINTPLPATTKGPEFRQAITENWLPALHKFKPQLILIS
EEEEECCCCCCEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
AGFDAHIEDEMSQISLTESDYRWVTDEIKIIADQYAEGRIVSMLEGGYALNALGRSVVEH
CCCCCCHHHHHHHEECCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
VKGLIGS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]