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The map label for this gene is iolS [H]

Identifier: 119946300

GI number: 119946300

Start: 3270015

End: 3270995

Strand: Reverse

Name: iolS [H]

Synonym: Ping_2668

Alternate gene names: 119946300

Gene position: 3270995-3270015 (Counterclockwise)

Preceding gene: 119946303

Following gene: 119946299

Centisome position: 71.74

GC content: 45.67

Gene sequence:

>981_bases
ATGGAACAACGTAAATTAGGTAAAAGCGGACTGTCTGGATCGGTCATTGGTTTAGGCTGTTGGCAGTTAGGGGGGGATTT
TGGTCCTGCCGGTGTTGAGAATAGCGAGCAAATTTTAAGTGCGGCCGATAGTGCAGGGATCACATTTTGGGATACTGCTG
ATGTCTATGGCGGTGGAGAAAGTGAAAAGAAAATAGGGGCTTGGCAACATGCACATCCCAAGCCACGCACTATTGTCACT
AAGCTTGGTCGTGATGGATCCCTTTACCCGGATAAATATACTGCTGAAAATATGCAGCGCAGTATTGAAGAGTCACTCGC
ACGTTTACAGGTAAATTGTCTAGATTTAGTACAGCTGCATTGCATTCCCCCTGCCGTGTTACAAGGTGATGCCGTATGGC
AAGCGCTGGAAGACTTTCGCTCGCAGGGGTTAATTAGGCATTACGGCGCGAGTGTTGAAAATATTAAAGAAGGGTTAATG
TGTCTGGATAAGCCGGGGTTAACTTCATTACAGATAATCTTTAACATATTCCGCCAGGATGCCGTTGAAAAATTATTACC
ACAAGCGGCAGCGGCTGATGTGGGGATTATTGCGCGCTTACCACTGGCCAGTGGTTTATTAAGCGGAAAATTTACTTTGG
ACACTGAATTTAGTAAAAGCGATCACCGTAACTTCAATAAAGACGGCGCGTTCTTTAATGTTGGTGAAACCTTCTCCGGT
TTACCCTATCCTAAAGCCATTGAATTAGTTAATAAGCTTAAAGGCTTGCTGCCTGCTGATATTCCATTAGCACAATTAGC
GTTACGTTGGCTGGTCGACCAACCTCAAGTCACCAGCGTTATTAGCGGCGCAAGCAGCGCGCAGCAAGTTCAGCTGAATG
CCAGCGTTGCCGGCATGGCACCTTTATCAAAATCCTTACACGAGTCATTATCCGACTTCTATTACTCGCAGGTCAGAGAA
CATGTTCGTGGTGATATTTAA

Upstream 100 bases:

>100_bases
CGATTTATTACAATAGTGATTAGCATCGAATGCGATTAGATTAGTGTTAATGTTTTGAAGTTATTTCTTGGTCGTCAATA
ATTGATAATAGGTGGCAATA

Downstream 100 bases:

>100_bases
CCGCTACTTTTATTAGCTAAACGCTCAAATCAGCGTAAAACGCTTGTAAAACAGGCAATTAAGGTAAATTATAAAGGATG
TTTAATCGTTCTAAAATCGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEQRKLGKSGLSGSVIGLGCWQLGGDFGPAGVENSEQILSAADSAGITFWDTADVYGGGESEKKIGAWQHAHPKPRTIVT
KLGRDGSLYPDKYTAENMQRSIEESLARLQVNCLDLVQLHCIPPAVLQGDAVWQALEDFRSQGLIRHYGASVENIKEGLM
CLDKPGLTSLQIIFNIFRQDAVEKLLPQAAAADVGIIARLPLASGLLSGKFTLDTEFSKSDHRNFNKDGAFFNVGETFSG
LPYPKAIELVNKLKGLLPADIPLAQLALRWLVDQPQVTSVISGASSAQQVQLNASVAGMAPLSKSLHESLSDFYYSQVRE
HVRGDI

Sequences:

>Translated_326_residues
MEQRKLGKSGLSGSVIGLGCWQLGGDFGPAGVENSEQILSAADSAGITFWDTADVYGGGESEKKIGAWQHAHPKPRTIVT
KLGRDGSLYPDKYTAENMQRSIEESLARLQVNCLDLVQLHCIPPAVLQGDAVWQALEDFRSQGLIRHYGASVENIKEGLM
CLDKPGLTSLQIIFNIFRQDAVEKLLPQAAAADVGIIARLPLASGLLSGKFTLDTEFSKSDHRNFNKDGAFFNVGETFSG
LPYPKAIELVNKLKGLLPADIPLAQLALRWLVDQPQVTSVISGASSAQQVQLNASVAGMAPLSKSLHESLSDFYYSQVRE
HVRGDI
>Mature_326_residues
MEQRKLGKSGLSGSVIGLGCWQLGGDFGPAGVENSEQILSAADSAGITFWDTADVYGGGESEKKIGAWQHAHPKPRTIVT
KLGRDGSLYPDKYTAENMQRSIEESLARLQVNCLDLVQLHCIPPAVLQGDAVWQALEDFRSQGLIRHYGASVENIKEGLM
CLDKPGLTSLQIIFNIFRQDAVEKLLPQAAAADVGIIARLPLASGLLSGKFTLDTEFSKSDHRNFNKDGAFFNVGETFSG
LPYPKAIELVNKLKGLLPADIPLAQLALRWLVDQPQVTSVISGASSAQQVQLNASVAGMAPLSKSLHESLSDFYYSQVRE
HVRGDI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=328, Percent_Identity=29.2682926829268, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4504825, Length=325, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI27436964, Length=322, Percent_Identity=26.3975155279503, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI27436971, Length=311, Percent_Identity=27.3311897106109, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI27436966, Length=322, Percent_Identity=26.3975155279503, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI27436962, Length=322, Percent_Identity=26.3975155279503, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1788070, Length=346, Percent_Identity=27.1676300578035, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081735, Length=317, Percent_Identity=26.813880126183, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789375, Length=351, Percent_Identity=28.2051282051282, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=28.9592760180996, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35290; Mature: 35290

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRKLGKSGLSGSVIGLGCWQLGGDFGPAGVENSEQILSAADSAGITFWDTADVYGGGE
CCCHHCCCCCCCCCEEEEEHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCC
SEKKIGAWQHAHPKPRTIVTKLGRDGSLYPDKYTAENMQRSIEESLARLQVNCLDLVQLH
CCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CIPPAVLQGDAVWQALEDFRSQGLIRHYGASVENIKEGLMCLDKPGLTSLQIIFNIFRQD
CCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AVEKLLPQAAAADVGIIARLPLASGLLSGKFTLDTEFSKSDHRNFNKDGAFFNVGETFSG
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCHHCCCCCCCCCEEECCCCCCC
LPYPKAIELVNKLKGLLPADIPLAQLALRWLVDQPQVTSVISGASSAQQVQLNASVAGMA
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECCCHHCCH
PLSKSLHESLSDFYYSQVREHVRGDI
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEQRKLGKSGLSGSVIGLGCWQLGGDFGPAGVENSEQILSAADSAGITFWDTADVYGGGE
CCCHHCCCCCCCCCEEEEEHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCC
SEKKIGAWQHAHPKPRTIVTKLGRDGSLYPDKYTAENMQRSIEESLARLQVNCLDLVQLH
CCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CIPPAVLQGDAVWQALEDFRSQGLIRHYGASVENIKEGLMCLDKPGLTSLQIIFNIFRQD
CCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AVEKLLPQAAAADVGIIARLPLASGLLSGKFTLDTEFSKSDHRNFNKDGAFFNVGETFSG
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCHHCCCCCCCCCEEECCCCCCC
LPYPKAIELVNKLKGLLPADIPLAQLALRWLVDQPQVTSVISGASSAQQVQLNASVAGMA
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECCCHHCCH
PLSKSLHESLSDFYYSQVREHVRGDI
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]