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The map label for this gene is sucD [H]

Identifier: 119945909

GI number: 119945909

Start: 2733371

End: 2734243

Strand: Reverse

Name: sucD [H]

Synonym: Ping_2249

Alternate gene names: 119945909

Gene position: 2734243-2733371 (Counterclockwise)

Preceding gene: 119945910

Following gene: 119945908

Centisome position: 59.97

GC content: 42.15

Gene sequence:

>873_bases
ATGAGCATTTTAATTAATAAAGACACTAAAGTAATTTGCCAGGGTTTCACTGGCGGACAAGGTACTTTCCACTCTGAGCA
AGCGCTTGAATACGGCACACAAATGGTCGGTGGTGTTTCACCGGGTAAAGGTGGTCAAACGCATTTAGGTCTTCCTGTAT
TTAATACGGTACGCGAAGCAGTTGAAAAAACAGGTGCGACAGCATCGGTTATCTATGTACCAGCTCCATTTTGTAAAGAT
GCCATATTAGAAGCGATTGACGCGGGTATTAAACTGATTGTTACCATTACTGAAGGTATTCCAACACTGGATTTAGTTAG
CGTTAAAGTTAAACTTGATCAAGCTGGTGTTGTTATGATTGGTCCTAACTGTCCTGGTGTTATCACTCCTGACGAATGTA
AGATTGGCATTATGCCTGGTCACATTCATCTAAAAGGTAAAGTAGGTATTGTTTCTCGCTCTGGGACATTAACTTACGAA
GCAGTTAAACAAACAACTGATGAAGGTTTTGGACAGTCTACTTGTGTGGGTATCGGTGGCGATCCTATCCCAGGTTCAAG
CTTTATTGATATCCTGAAACTTTTCCAGGAAGATCCTGAAACTGAAGCTATTGTTATGATTGGTGAGATTGGTGGTACTG
CGGAAGAAGAAGCCGCTGCATTTATCAAAGCAAATGTGACTAAACCTGTCGTATCTTATATTGCCGGTGTTACTGCACCT
GCAGGTAAGCGTATGGGACATGCCGGTGCAATCATTGCCGGTGGTAAAGGGACTGCCGATGATAAGTTTAAAGCACTTGA
AGATGCTGGTGTTAAAACCACTAAATCACTTGCTCAGATTGGTCAAGCATTACGTGAAGTAACAGGTTGGTAA

Upstream 100 bases:

>100_bases
TAGGTCGTAAAATTCTTGCAGAATCTGGTCTTAATATTATCGCAGCTGCATCATTAACAGATGCTGCTGAGCAAGCGGTT
AAAGCGGTAGGTGGCAAATA

Downstream 100 bases:

>100_bases
TTACCCGCTGATATTTTTAGATATTTTTGTATCAATAGTCTCAAAACCTCGTTATTTAACGGGGTTTTTTTATTTCAAAA
ATAAATATATTTCGTGGTTA

Product: succinyl-CoA synthetase, alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSILINKDTKVICQGFTGGQGTFHSEQALEYGTQMVGGVSPGKGGQTHLGLPVFNTVREAVEKTGATASVIYVPAPFCKD
AILEAIDAGIKLIVTITEGIPTLDLVSVKVKLDQAGVVMIGPNCPGVITPDECKIGIMPGHIHLKGKVGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGSSFIDILKLFQEDPETEAIVMIGEIGGTAEEEAAAFIKANVTKPVVSYIAGVTAP
AGKRMGHAGAIIAGGKGTADDKFKALEDAGVKTTKSLAQIGQALREVTGW

Sequences:

>Translated_290_residues
MSILINKDTKVICQGFTGGQGTFHSEQALEYGTQMVGGVSPGKGGQTHLGLPVFNTVREAVEKTGATASVIYVPAPFCKD
AILEAIDAGIKLIVTITEGIPTLDLVSVKVKLDQAGVVMIGPNCPGVITPDECKIGIMPGHIHLKGKVGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGSSFIDILKLFQEDPETEAIVMIGEIGGTAEEEAAAFIKANVTKPVVSYIAGVTAP
AGKRMGHAGAIIAGGKGTADDKFKALEDAGVKTTKSLAQIGQALREVTGW
>Mature_289_residues
SILINKDTKVICQGFTGGQGTFHSEQALEYGTQMVGGVSPGKGGQTHLGLPVFNTVREAVEKTGATASVIYVPAPFCKDA
ILEAIDAGIKLIVTITEGIPTLDLVSVKVKLDQAGVVMIGPNCPGVITPDECKIGIMPGHIHLKGKVGIVSRSGTLTYEA
VKQTTDEGFGQSTCVGIGGDPIPGSSFIDILKLFQEDPETEAIVMIGEIGGTAEEEAAAFIKANVTKPVVSYIAGVTAPA
GKRMGHAGAIIAGGKGTADDKFKALEDAGVKTTKSLAQIGQALREVTGW

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=284, Percent_Identity=68.3098591549296, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI38569423, Length=260, Percent_Identity=34.2307692307692, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI38569421, Length=260, Percent_Identity=34.2307692307692, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1786949, Length=287, Percent_Identity=85.0174216027875, Blast_Score=492, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=64.5833333333333, Blast_Score=348, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17553126, Length=290, Percent_Identity=63.7931034482759, Blast_Score=343, Evalue=5e-95,
Organism=Caenorhabditis elegans, GI17557344, Length=256, Percent_Identity=30.078125, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17551266, Length=256, Percent_Identity=29.296875, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=54.1095890410959, Blast_Score=287, Evalue=1e-78,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=60, Blast_Score=339, Evalue=1e-93,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=61.8055555555556, Blast_Score=323, Evalue=8e-89,
Organism=Drosophila melanogaster, GI281363477, Length=259, Percent_Identity=30.8880308880309, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363475, Length=259, Percent_Identity=30.8880308880309, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363473, Length=259, Percent_Identity=30.8880308880309, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29920; Mature: 29789

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVICQGFTGGQGTFHSEQALEYGTQMVGGVSPGKGGQTHLGLPVFNTVREA
CEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
VEKTGATASVIYVPAPFCKDAILEAIDAGIKLIVTITEGIPTLDLVSVKVKLDQAGVVMI
HHHCCCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEEEECCCCEEEE
GPNCPGVITPDECKIGIMPGHIHLKGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCCCCCCCCEEEEECCEEEEEEEEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGSSFIDILKLFQEDPETEAIVMIGEIGGTAEEEAAAFIKANVTKPVVSYIAGVTAP
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCC
AGKRMGHAGAIIAGGKGTADDKFKALEDAGVKTTKSLAQIGQALREVTGW
CCCCCCCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILINKDTKVICQGFTGGQGTFHSEQALEYGTQMVGGVSPGKGGQTHLGLPVFNTVREA
EEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
VEKTGATASVIYVPAPFCKDAILEAIDAGIKLIVTITEGIPTLDLVSVKVKLDQAGVVMI
HHHCCCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEEEECCCCEEEE
GPNCPGVITPDECKIGIMPGHIHLKGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCCCCCCCCEEEEECCEEEEEEEEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGSSFIDILKLFQEDPETEAIVMIGEIGGTAEEEAAAFIKANVTKPVVSYIAGVTAP
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCC
AGKRMGHAGAIIAGGKGTADDKFKALEDAGVKTTKSLAQIGQALREVTGW
CCCCCCCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]