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The map label for this gene is sucC

Identifier: 119945910

GI number: 119945910

Start: 2734243

End: 2735409

Strand: Reverse

Name: sucC

Synonym: Ping_2250

Alternate gene names: 119945910

Gene position: 2735409-2734243 (Counterclockwise)

Preceding gene: 119945911

Following gene: 119945909

Centisome position: 59.99

GC content: 42.07

Gene sequence:

>1167_bases
ATGAATTTGCATGAATATCAGGCAAAACAGTTGTTCAGAGAATATGGATTACCTGTACCACAAGGTATCGCATGCGATAC
CGCTGAGGAAGCAGTAAGTGCAGCCTCTCAAATTGGTGGAGACAAATGGGTTATCAAGTGTCAGGTACATGCAGGTGGCC
GTGGTAAAGCCGGTGGTGTTGAGTTAGTTAGCACTAAAGATGGTTTACGTGAGTTTGCACATAAATGGTTAGGTAAGAAC
TTAGTTACTTTCCAAACCGATGCAAACGGTCAACCGGTTAATAAGTTATTAGTAGAAAGCTGTAGTGATATTGCTAATGA
GCTTTACTTAGGTGCGGTTATTGACCGTGCTTCACAACGTGTTACTTTTATGGCATCGACAGAAGGTGGTGTAGAAATTG
AGAAAGTAGCAGAAGAGACGCCTGAGCTTATTCATACCGCAATGATTGATCCATTAGTGGGCGCACAAGCGTACCAAGGT
CGTGAACTTGCCTTTAAATTAGGTCTTTCTGGTAAACAGATTGGTCAATTTACAAAAATCTTTCTGGGTCTTGCGACTCT
TTTTGAAGAGAAAGATTTATCGTTATTAGAAATCAATCCACTGGTTGTGACTGCACAAGACGATCTTATCTGTTTAGACG
GTAAAATTTCTATCGATTCTAACGCAATGTACCGTCAAAAAGCGTTACATGCGATAAACGATACAACGCAAGATGATGAA
CGTGAAATGCATGCTGCACAATGGGAACTTAACTATGTTGCTCTTGATGGTAGCATCGGCTGTATGGTAAACGGTGCCGG
CCTTGCAATGGGAACAATGGATATCGTGCATTTACACGGTGGTAATCCGGCTAACTTCCTGGACGTAGGCGGCGGTGCAA
CCAAAGAACGTGTTACCGAAGCTTTCAAAATCATTCTTTCTGACGATAATGTTAAAGCTGTTTTAGTAAACATCTTTGGC
GGTATTGTACGTTGTGATTTAATTGCTGACGGTGTCATTGGCGCAGTAGCTGAAGTTGGTGTAACAGTGCCTGTTATCGT
GCGTTTAGAAGGCAACAATGCTGATTTAGGTCGTAAAATTCTTGCAGAATCTGGTCTTAATATTATCGCAGCTGCATCAT
TAACAGATGCTGCTGAGCAAGCGGTTAAAGCGGTAGGTGGCAAATAA

Upstream 100 bases:

>100_bases
ATTTAGTCAATATAACCGGCGCTAACGTAAGTAACATTACTTCGAGTTATGACCTGATTAATAGGGTCATTAAGTTAAAC
CAAATAAATGGATAAGAATC

Downstream 100 bases:

>100_bases
TGAGCATTTTAATTAATAAAGACACTAAAGTAATTTGCCAGGGTTTCACTGGCGGACAAGGTACTTTCCACTCTGAGCAA
GCGCTTGAATACGGCACACA

Product: succinyl-CoA synthetase, beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKQLFREYGLPVPQGIACDTAEEAVSAASQIGGDKWVIKCQVHAGGRGKAGGVELVSTKDGLREFAHKWLGKN
LVTFQTDANGQPVNKLLVESCSDIANELYLGAVIDRASQRVTFMASTEGGVEIEKVAEETPELIHTAMIDPLVGAQAYQG
RELAFKLGLSGKQIGQFTKIFLGLATLFEEKDLSLLEINPLVVTAQDDLICLDGKISIDSNAMYRQKALHAINDTTQDDE
REMHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVHLHGGNPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFG
GIVRCDLIADGVIGAVAEVGVTVPVIVRLEGNNADLGRKILAESGLNIIAAASLTDAAEQAVKAVGGK

Sequences:

>Translated_388_residues
MNLHEYQAKQLFREYGLPVPQGIACDTAEEAVSAASQIGGDKWVIKCQVHAGGRGKAGGVELVSTKDGLREFAHKWLGKN
LVTFQTDANGQPVNKLLVESCSDIANELYLGAVIDRASQRVTFMASTEGGVEIEKVAEETPELIHTAMIDPLVGAQAYQG
RELAFKLGLSGKQIGQFTKIFLGLATLFEEKDLSLLEINPLVVTAQDDLICLDGKISIDSNAMYRQKALHAINDTTQDDE
REMHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVHLHGGNPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFG
GIVRCDLIADGVIGAVAEVGVTVPVIVRLEGNNADLGRKILAESGLNIIAAASLTDAAEQAVKAVGGK
>Mature_388_residues
MNLHEYQAKQLFREYGLPVPQGIACDTAEEAVSAASQIGGDKWVIKCQVHAGGRGKAGGVELVSTKDGLREFAHKWLGKN
LVTFQTDANGQPVNKLLVESCSDIANELYLGAVIDRASQRVTFMASTEGGVEIEKVAEETPELIHTAMIDPLVGAQAYQG
RELAFKLGLSGKQIGQFTKIFLGLATLFEEKDLSLLEINPLVVTAQDDLICLDGKISIDSNAMYRQKALHAINDTTQDDE
REMHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVHLHGGNPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFG
GIVRCDLIADGVIGAVAEVGVTVPVIVRLEGNNADLGRKILAESGLNIIAAASLTDAAEQAVKAVGGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=44.3589743589744, Blast_Score=331, Evalue=8e-91,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=42.2976501305483, Blast_Score=306, Evalue=3e-83,
Organism=Homo sapiens, GI294862256, Length=358, Percent_Identity=42.1787709497207, Blast_Score=289, Evalue=2e-78,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=75.7731958762887, Blast_Score=590, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=45.3846153846154, Blast_Score=320, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=43.1472081218274, Blast_Score=315, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=40.4580152671756, Blast_Score=313, Evalue=2e-86,
Organism=Drosophila melanogaster, GI161078106, Length=389, Percent_Identity=43.7017994858612, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24645208, Length=389, Percent_Identity=43.7017994858612, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI281361397, Length=390, Percent_Identity=43.5897435897436, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI281361395, Length=390, Percent_Identity=43.5897435897436, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=41.2658227848101, Blast_Score=299, Evalue=2e-81,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_PSYIN (A1SWX6)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_943590.1
- ProteinModelPortal:   A1SWX6
- SMR:   A1SWX6
- STRING:   A1SWX6
- GeneID:   4623460
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2250
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- PhylomeDB:   A1SWX6
- BioCyc:   PING357804:PING_2250-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41210; Mature: 41210

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFREYGLPVPQGIACDTAEEAVSAASQIGGDKWVIKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
ELVSTKDGLREFAHKWLGKNLVTFQTDANGQPVNKLLVESCSDIANELYLGAVIDRASQR
EEEECHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VTFMASTEGGVEIEKVAEETPELIHTAMIDPLVGAQAYQGRELAFKLGLSGKQIGQFTKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHH
FLGLATLFEEKDLSLLEINPLVVTAQDDLICLDGKISIDSNAMYRQKALHAINDTTQDDE
HHHHHHHHCCCCCCEEEECCEEEEECCCEEEECCEEEECCCHHHHHHHHHHHCCCCCCHH
REMHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVHLHGGNPANFLDVGGGATKERVTE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEEECCCCCCEEECCCCCCHHHHHH
AFKIILSDDNVKAVLVNIFGGIVRCDLIADGVIGAVAEVGVTVPVIVRLEGNNADLGRKI
HHEEEECCCCCEEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHH
LAESGLNIIAAASLTDAAEQAVKAVGGK
HHHCCCCEEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKQLFREYGLPVPQGIACDTAEEAVSAASQIGGDKWVIKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
ELVSTKDGLREFAHKWLGKNLVTFQTDANGQPVNKLLVESCSDIANELYLGAVIDRASQR
EEEECHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VTFMASTEGGVEIEKVAEETPELIHTAMIDPLVGAQAYQGRELAFKLGLSGKQIGQFTKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHH
FLGLATLFEEKDLSLLEINPLVVTAQDDLICLDGKISIDSNAMYRQKALHAINDTTQDDE
HHHHHHHHCCCCCCEEEECCEEEEECCCEEEECCEEEECCCHHHHHHHHHHHCCCCCCHH
REMHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVHLHGGNPANFLDVGGGATKERVTE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEEECCCCCCEEECCCCCCHHHHHH
AFKIILSDDNVKAVLVNIFGGIVRCDLIADGVIGAVAEVGVTVPVIVRLEGNNADLGRKI
HHEEEECCCCCEEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHH
LAESGLNIIAAASLTDAAEQAVKAVGGK
HHHCCCCEEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA