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The map label for this gene is phoR [H]

Identifier: 119945891

GI number: 119945891

Start: 2714062

End: 2715384

Strand: Reverse

Name: phoR [H]

Synonym: Ping_2231

Alternate gene names: 119945891

Gene position: 2715384-2714062 (Counterclockwise)

Preceding gene: 119945892

Following gene: 119945890

Centisome position: 59.55

GC content: 39.08

Gene sequence:

>1323_bases
TTGAAAGCTTTTACCGCAAAACATCAAATTATCGCATTGTCTGTTTTTTATGCCCCAATTATTATTTTAGGTATTGTTTT
TAATTGTTTAAAAGACTTATTACTGGTTTCCTTGTTTGCCCATATTGTGTGGCATTATTATTACCTGAAAAAATTAAATA
ACTGGTTATGGTTTGATAAAAGCACCATCCTGCCCAAGGGTAAATTAGACTGGCAACATGCATTTAATGGCCTTCATAAT
ATGCAGCAAAGGCATCGCAAACGTCGTAATGATTTGGCCGGTATCATTCGCCGTTTTAGTGAAGGTTCAGAAGCGCTTTC
AGATGGGGTGATAGTTTATGCGAAAAGCGGGGGTATTGTTTGGTCCAATCGTTTGGCACAATTTCAACTGGGTTTTAAGC
GAACCGATAATTCGGGTTTTTCTCGTAAAGAAGTTTCAGGAGAACATATTACCTCCCTAGTACCTGATCCTGAATTTTTG
GCATTTTTAAAACGTGATGATTCTTCTGAATTATTAGAGTTACCTTCTCCTATTCACGCAGATAAATTACTTGAATTTAG
TGTTATGCCCTACGCAAAACACAAACGTTTATTGATTGTTCGAGACGTGACCAGTTATCGAGAGATGGACGAAATGCGTC
GTCGTTTTGTGGCCAACGTCTCTCATGAATTGCGCACCCCGTTAACGGTATTACAAGGTTACATTGAAATATTGGATATG
CAGCTGGTGGACAGTCCGCAACAATCAAAAACGCTGACTATTTTAGACCAGCAGACAAAACGAATGTGTGCGTTGGTAGA
GCAGATAATGATTTTGTCTAAAATAGAAGGTGCAGGCAGTGTTGATTTAAATACCGTGGTTAATGTTCCTTTTTTGCTTA
AGCAGATTGAAAATGAAGCGATTGAATTAGGAAAAAATAAATCTTTAACCATTAAATTTGAAATAGATCCGAACTTGCAT
TTGCTGGGTGATGAGATGCAGTTACGCAGTGTGATGGCAAATTTAATCTATAACGCCATTAACTATACACCTGAGCATGG
TTCAGTTAAGGTGCGATGGCGTCTTTCCTGTAAAACCGGTGGCCATTTTTCTGTGGTTGATGATGGAGAAGGCATTGCTG
AAGAGCATCTTCATCGTCTTACGGAGCGCTTCTATCGTGTTGAAGGTTCGCGTTCTAGAGATACCGGCGGTTCCGGTTTG
GGTCTCTCTATTGTCAAACATACCCTGAGTCATTACGGCTGTGAATTAAAGGTACAAAGTACAATAGGGGTGGGCAGTCA
ATTTTCTTTTATTATCCCAACACGTTATCTGATAGAAAAATAA

Upstream 100 bases:

>100_bases
AAGGGCCTAAACTATCCACGGCTCACCGTGCTGATTTTGATCATCGAAACGTTTTTAATCACTTGATAAATCAGTAATTT
ATATTAATAGAGTTATTACT

Downstream 100 bases:

>100_bases
AACAGACTATCGTTATCAAACAAGACAGAATGAAGCATAAATAACGTTATACTTTTTAAAAATAAAAATTTAATCTACTG
GAGTGCCTATGAATAATCAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKAFTAKHQIIALSVFYAPIIILGIVFNCLKDLLLVSLFAHIVWHYYYLKKLNNWLWFDKSTILPKGKLDWQHAFNGLHN
MQQRHRKRRNDLAGIIRRFSEGSEALSDGVIVYAKSGGIVWSNRLAQFQLGFKRTDNSGFSRKEVSGEHITSLVPDPEFL
AFLKRDDSSELLELPSPIHADKLLEFSVMPYAKHKRLLIVRDVTSYREMDEMRRRFVANVSHELRTPLTVLQGYIEILDM
QLVDSPQQSKTLTILDQQTKRMCALVEQIMILSKIEGAGSVDLNTVVNVPFLLKQIENEAIELGKNKSLTIKFEIDPNLH
LLGDEMQLRSVMANLIYNAINYTPEHGSVKVRWRLSCKTGGHFSVVDDGEGIAEEHLHRLTERFYRVEGSRSRDTGGSGL
GLSIVKHTLSHYGCELKVQSTIGVGSQFSFIIPTRYLIEK

Sequences:

>Translated_440_residues
MKAFTAKHQIIALSVFYAPIIILGIVFNCLKDLLLVSLFAHIVWHYYYLKKLNNWLWFDKSTILPKGKLDWQHAFNGLHN
MQQRHRKRRNDLAGIIRRFSEGSEALSDGVIVYAKSGGIVWSNRLAQFQLGFKRTDNSGFSRKEVSGEHITSLVPDPEFL
AFLKRDDSSELLELPSPIHADKLLEFSVMPYAKHKRLLIVRDVTSYREMDEMRRRFVANVSHELRTPLTVLQGYIEILDM
QLVDSPQQSKTLTILDQQTKRMCALVEQIMILSKIEGAGSVDLNTVVNVPFLLKQIENEAIELGKNKSLTIKFEIDPNLH
LLGDEMQLRSVMANLIYNAINYTPEHGSVKVRWRLSCKTGGHFSVVDDGEGIAEEHLHRLTERFYRVEGSRSRDTGGSGL
GLSIVKHTLSHYGCELKVQSTIGVGSQFSFIIPTRYLIEK
>Mature_440_residues
MKAFTAKHQIIALSVFYAPIIILGIVFNCLKDLLLVSLFAHIVWHYYYLKKLNNWLWFDKSTILPKGKLDWQHAFNGLHN
MQQRHRKRRNDLAGIIRRFSEGSEALSDGVIVYAKSGGIVWSNRLAQFQLGFKRTDNSGFSRKEVSGEHITSLVPDPEFL
AFLKRDDSSELLELPSPIHADKLLEFSVMPYAKHKRLLIVRDVTSYREMDEMRRRFVANVSHELRTPLTVLQGYIEILDM
QLVDSPQQSKTLTILDQQTKRMCALVEQIMILSKIEGAGSVDLNTVVNVPFLLKQIENEAIELGKNKSLTIKFEIDPNLH
LLGDEMQLRSVMANLIYNAINYTPEHGSVKVRWRLSCKTGGHFSVVDDGEGIAEEHLHRLTERFYRVEGSRSRDTGGSGL
GLSIVKHTLSHYGCELKVQSTIGVGSQFSFIIPTRYLIEK

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=419, Percent_Identity=45.5847255369928, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1788393, Length=217, Percent_Identity=34.1013824884793, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=30.0847457627119, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=28.0172413793103, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=30.1801801801802, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=25.9911894273128, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI48994928, Length=267, Percent_Identity=28.4644194756554, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788549, Length=398, Percent_Identity=24.8743718592965, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=30.9417040358744, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082128, Length=242, Percent_Identity=26.0330578512397, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789403, Length=207, Percent_Identity=29.4685990338164, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=25.5813953488372, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=29.957805907173, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=213, Percent_Identity=28.6384976525822, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787894, Length=221, Percent_Identity=28.0542986425339, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788279, Length=202, Percent_Identity=28.2178217821782, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790551, Length=207, Percent_Identity=28.9855072463768, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50210; Mature: 50210

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFTAKHQIIALSVFYAPIIILGIVFNCLKDLLLVSLFAHIVWHYYYLKKLNNWLWFDK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
STILPKGKLDWQHAFNGLHNMQQRHRKRRNDLAGIIRRFSEGSEALSDGVIVYAKSGGIV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEECCCEE
WSNRLAQFQLGFKRTDNSGFSRKEVSGEHITSLVPDPEFLAFLKRDDSSELLELPSPIHA
ECCCHHHHEECEEECCCCCCCCHHCCCHHHHHCCCCHHHHHHHHCCCCHHHHHCCCCCCH
DKLLEFSVMPYAKHKRLLIVRDVTSYREMDEMRRRFVANVSHELRTPLTVLQGYIEILDM
HHHHHEECCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QLVDSPQQSKTLTILDQQTKRMCALVEQIMILSKIEGAGSVDLNTVVNVPFLLKQIENEA
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
IELGKNKSLTIKFEIDPNLHLLGDEMQLRSVMANLIYNAINYTPEHGSVKVRWRLSCKTG
HHCCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
GHFSVVDDGEGIAEEHLHRLTERFYRVEGSRSRDTGGSGLGLSIVKHTLSHYGCELKVQS
CEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEC
TIGVGSQFSFIIPTRYLIEK
CCCCCCCEEEECCCHHHHCC
>Mature Secondary Structure
MKAFTAKHQIIALSVFYAPIIILGIVFNCLKDLLLVSLFAHIVWHYYYLKKLNNWLWFDK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
STILPKGKLDWQHAFNGLHNMQQRHRKRRNDLAGIIRRFSEGSEALSDGVIVYAKSGGIV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEECCCEE
WSNRLAQFQLGFKRTDNSGFSRKEVSGEHITSLVPDPEFLAFLKRDDSSELLELPSPIHA
ECCCHHHHEECEEECCCCCCCCHHCCCHHHHHCCCCHHHHHHHHCCCCHHHHHCCCCCCH
DKLLEFSVMPYAKHKRLLIVRDVTSYREMDEMRRRFVANVSHELRTPLTVLQGYIEILDM
HHHHHEECCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QLVDSPQQSKTLTILDQQTKRMCALVEQIMILSKIEGAGSVDLNTVVNVPFLLKQIENEA
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
IELGKNKSLTIKFEIDPNLHLLGDEMQLRSVMANLIYNAINYTPEHGSVKVRWRLSCKTG
HHCCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
GHFSVVDDGEGIAEEHLHRLTERFYRVEGSRSRDTGGSGLGLSIVKHTLSHYGCELKVQS
CEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEC
TIGVGSQFSFIIPTRYLIEK
CCCCCCCEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3550103; 9278503; 2187152; 8391104 [H]