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The map label for this gene is alr2 [H]

Identifier: 119945753

GI number: 119945753

Start: 2534042

End: 2535169

Strand: Direct

Name: alr2 [H]

Synonym: Ping_2084

Alternate gene names: 119945753

Gene position: 2534042-2535169 (Clockwise)

Preceding gene: 119945752

Following gene: 119945754

Centisome position: 55.58

GC content: 44.24

Gene sequence:

>1128_bases
GTGAATTATAAAAACACGCATTTAACCAGAGCAATTATACATCTCGACCACCTGACTCATAATATGAAGGTGCTGCAAAA
AAAGGCCGGTAAGCGGCCACTTTTCCCCGCTATTAAGGCTAATGCCTACGGTCATGATGCAGAGATTATTGCAAAACATC
TGATCAGTCTTGGCTACACCACCTTATGCACCGCGCATCTAAGTGAGGCTGCAGAGCTTGTCGAAAAAGGGGTTAACGCT
ACATTTATCATCCTGTCACCCACGCTTGCTGAAAACAGCGACTATCTCCTTGACTATGATTTTCAACCGATAGTTTCTAG
CCAGGTGCAATTACAAGCGCTTGCCCAAGCAGCAAGAAGAAGAGATAAACAAATAACCATACACGTCAAAGTAGATACCG
GAATGGGCCGCATGGGTGTCAGACCCGACCAGCTACTGATGTTTCTTGATGAGTGTAAAGCCCAACCTGAAATTATTATT
GGAGGAGTCTGCAGCCATTTCCCCCGCGCTGATGAAAACAATTTATCTTTTTCAAAAACACAGATCAATACTTTCACTGC
GCTAAAGAAAGAAACCAAAGCGTATAATATTCCTCTCTATCATATTGCCAACAGTGCAGCCCTGTTTGCGTTAGAAGAAG
CACACCTTGATGCAATTCGTCCAGGTATATCAATCTATGGTCTAAAGCCATCTGTCTCTATGGTTGTCCCGGAGTTAAAC
GATCTTAAGCCGATAATGTCTCTTGTAAGCCGGATAACGCTGCTCAAGGAAGTCGTTCAAGATACCGGAATCAGTTATGG
CCACCTGCACTACACCGATAAACCCTCTCTTATCGCCACTATTCCCATTGGATATGGTGATGGTTTGAGCAGGTCGCTGA
GCAACAGAATTGAAGTTTTAATTGGTAACGAGCGATGCAGGCAGATTGGGAATATCTGTATGGATCAGTGCATGATTGAT
GTGACGCAACTTCGGGGTAAAGTCTCAATAGGGGACGAGGTTGTTATTATCGGAACTCAGGGCAGTGAAACCATAACAGC
CGATGATCTCGCAAAAAAACAGCACACAGTAAATTATGAGATAGTCACTGCGATCTCCAGTCGAGTGCCAAGAATAGTCG
CTCAATGA

Upstream 100 bases:

>100_bases
TTAATGCGGGTCATCGGGCTCGCATTTTTTTTACCCTATAGAAAAAAGATAGGGTAGCCAAAATTTTTTTATTATGATCT
AAATGGGAGCGACCAGCACT

Downstream 100 bases:

>100_bases
CCTGCATGAGTTATCTCTTATCTCATCGTAGTGTAATAATATACATATAATTAGGCTAAATTTTCAGACGTAAGATAATA
CCAAAAGAAGTTAAATTGTG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNYKNTHLTRAIIHLDHLTHNMKVLQKKAGKRPLFPAIKANAYGHDAEIIAKHLISLGYTTLCTAHLSEAAELVEKGVNA
TFIILSPTLAENSDYLLDYDFQPIVSSQVQLQALAQAARRRDKQITIHVKVDTGMGRMGVRPDQLLMFLDECKAQPEIII
GGVCSHFPRADENNLSFSKTQINTFTALKKETKAYNIPLYHIANSAALFALEEAHLDAIRPGISIYGLKPSVSMVVPELN
DLKPIMSLVSRITLLKEVVQDTGISYGHLHYTDKPSLIATIPIGYGDGLSRSLSNRIEVLIGNERCRQIGNICMDQCMID
VTQLRGKVSIGDEVVIIGTQGSETITADDLAKKQHTVNYEIVTAISSRVPRIVAQ

Sequences:

>Translated_375_residues
MNYKNTHLTRAIIHLDHLTHNMKVLQKKAGKRPLFPAIKANAYGHDAEIIAKHLISLGYTTLCTAHLSEAAELVEKGVNA
TFIILSPTLAENSDYLLDYDFQPIVSSQVQLQALAQAARRRDKQITIHVKVDTGMGRMGVRPDQLLMFLDECKAQPEIII
GGVCSHFPRADENNLSFSKTQINTFTALKKETKAYNIPLYHIANSAALFALEEAHLDAIRPGISIYGLKPSVSMVVPELN
DLKPIMSLVSRITLLKEVVQDTGISYGHLHYTDKPSLIATIPIGYGDGLSRSLSNRIEVLIGNERCRQIGNICMDQCMID
VTQLRGKVSIGDEVVIIGTQGSETITADDLAKKQHTVNYEIVTAISSRVPRIVAQ
>Mature_375_residues
MNYKNTHLTRAIIHLDHLTHNMKVLQKKAGKRPLFPAIKANAYGHDAEIIAKHLISLGYTTLCTAHLSEAAELVEKGVNA
TFIILSPTLAENSDYLLDYDFQPIVSSQVQLQALAQAARRRDKQITIHVKVDTGMGRMGVRPDQLLMFLDECKAQPEIII
GGVCSHFPRADENNLSFSKTQINTFTALKKETKAYNIPLYHIANSAALFALEEAHLDAIRPGISIYGLKPSVSMVVPELN
DLKPIMSLVSRITLLKEVVQDTGISYGHLHYTDKPSLIATIPIGYGDGLSRSLSNRIEVLIGNERCRQIGNICMDQCMID
VTQLRGKVSIGDEVVIIGTQGSETITADDLAKKQHTVNYEIVTAISSRVPRIVAQ

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=367, Percent_Identity=28.8828337874659, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=28.7262872628726, Blast_Score=138, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41389; Mature: 41389

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKNTHLTRAIIHLDHLTHNMKVLQKKAGKRPLFPAIKANAYGHDAEIIAKHLISLGYT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCHH
TLCTAHLSEAAELVEKGVNATFIILSPTLAENSDYLLDYDFQPIVSSQVQLQALAQAARR
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHC
RDKQITIHVKVDTGMGRMGVRPDQLLMFLDECKAQPEIIIGGVCSHFPRADENNLSFSKT
CCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCCEEHH
QINTFTALKKETKAYNIPLYHIANSAALFALEEAHLDAIRPGISIYGLKPSVSMVVPELN
HHHHHHHHHHHCCEECCEEEEECCCEEEEEEHHHHHHHHCCCCEEEECCCCCEEECCCCC
DLKPIMSLVSRITLLKEVVQDTGISYGHLHYTDKPSLIATIPIGYGDGLSRSLSNRIEVL
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHCCEEEE
IGNERCRQIGNICMDQCMIDVTQLRGKVSIGDEVVIIGTQGSETITADDLAKKQHTVNYE
ECCHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCEEEHHHHHHHHHCCCHH
IVTAISSRVPRIVAQ
HHHHHHHHCCHHHCC
>Mature Secondary Structure
MNYKNTHLTRAIIHLDHLTHNMKVLQKKAGKRPLFPAIKANAYGHDAEIIAKHLISLGYT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCHH
TLCTAHLSEAAELVEKGVNATFIILSPTLAENSDYLLDYDFQPIVSSQVQLQALAQAARR
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHC
RDKQITIHVKVDTGMGRMGVRPDQLLMFLDECKAQPEIIIGGVCSHFPRADENNLSFSKT
CCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCCEEHH
QINTFTALKKETKAYNIPLYHIANSAALFALEEAHLDAIRPGISIYGLKPSVSMVVPELN
HHHHHHHHHHHCCEECCEEEEECCCEEEEEEHHHHHHHHCCCCEEEECCCCCEEECCCCC
DLKPIMSLVSRITLLKEVVQDTGISYGHLHYTDKPSLIATIPIGYGDGLSRSLSNRIEVL
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHCCEEEE
IGNERCRQIGNICMDQCMIDVTQLRGKVSIGDEVVIIGTQGSETITADDLAKKQHTVNYE
ECCHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCEEEHHHHHHHHHCCCHH
IVTAISSRVPRIVAQ
HHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]