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The map label for this gene is dhaAF [H]

Identifier: 119945682

GI number: 119945682

Start: 2429632

End: 2430513

Strand: Direct

Name: dhaAF [H]

Synonym: Ping_1998

Alternate gene names: 119945682

Gene position: 2429632-2430513 (Clockwise)

Preceding gene: 119945681

Following gene: 119945683

Centisome position: 53.29

GC content: 40.59

Gene sequence:

>882_bases
ATGAATCTAGATACTTTATTTCCTTTTAAACGCAATTATTTAGATCGTAATGGTCAGCAGTACCATTACCTAAATGAAGG
TTCAGGTGAGCCGGTTGTGATGGTACACGGTAACCCGAGTTGGTCTTTTTATTACCGCAACTTAGTCAAATCATTAAGCC
GCAATTACCAATGTGTTGTACCTGATCATATTGGTTGCGGATTATCCGATAAACCCGCGGATAAAGATTATCAATACACA
CTCAAAAATCGCATCGATGATTTAGAGGCATTATTGGATTCGCTTAACATCAATGAAAATATTACCTTGGTTGTCCATGA
TTGGGGCGGCATGATAGGCATGGGTTACGCGGCGCGACATCCAGAACGTATTAAACGTTTAGTTATTTTAAATACCGCGG
CTTTTCATCTGCCCAGCACTAAATCGTTTCCTGTTCCATTATTGATTGGTCGAAATACCTACATTGGAACCGTTTTAATA
CGCGGATTAAATGCCTTTTCAGCGATAGCATCCTATGTGGGCGTAAAACGCAAACCCATGGAAAAAGCGGTTCGACAAGC
TTATGTCGCACCCTTTAATTCATGGAAAAACCGCATTTCCACGCTCAGATTCGTACAAGATATCCCGCTTTTACCGCATC
ATAAAAATTACCAGTTAGTCTCGGATATCAGCGACAGCTTGATTCACTTTCAGAAAATACCCACCATCATCTGCTGGGGA
ATGAAAGATTTTGTGTTCGATAAACATTTCCTGAATACCTGGAAAGAAAAAATGCCCCATGCTGTGGTTCATGAGTTTGA
CGATTGTGGTCATTATATTCTGGAAGATGCCAGTGAACAGGTGATCCCGCTTATTGAAACATTTATGGCAGAAAACCCTT
AA

Upstream 100 bases:

>100_bases
ATAGCGCATGATCAGGGATTTCTGGTTAAAGGCGATAAAGTGAGCTTTTTGGGCATAGGCAGCGGACTGAACTGCATGAT
GTTAGGACTTGAGTGGTAAT

Downstream 100 bases:

>100_bases
CTTATGTCCGATCATCAATACTGCAACTTTTGCCGTCATTTAATCGATGCGGCAACGGCTTTCCCTGACTCCCTAGCAGT
TGCGGTTCAAAAAAAACGAT

Product: alpha/beta hydrolase fold

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNLDTLFPFKRNYLDRNGQQYHYLNEGSGEPVVMVHGNPSWSFYYRNLVKSLSRNYQCVVPDHIGCGLSDKPADKDYQYT
LKNRIDDLEALLDSLNINENITLVVHDWGGMIGMGYAARHPERIKRLVILNTAAFHLPSTKSFPVPLLIGRNTYIGTVLI
RGLNAFSAIASYVGVKRKPMEKAVRQAYVAPFNSWKNRISTLRFVQDIPLLPHHKNYQLVSDISDSLIHFQKIPTIICWG
MKDFVFDKHFLNTWKEKMPHAVVHEFDDCGHYILEDASEQVIPLIETFMAENP

Sequences:

>Translated_293_residues
MNLDTLFPFKRNYLDRNGQQYHYLNEGSGEPVVMVHGNPSWSFYYRNLVKSLSRNYQCVVPDHIGCGLSDKPADKDYQYT
LKNRIDDLEALLDSLNINENITLVVHDWGGMIGMGYAARHPERIKRLVILNTAAFHLPSTKSFPVPLLIGRNTYIGTVLI
RGLNAFSAIASYVGVKRKPMEKAVRQAYVAPFNSWKNRISTLRFVQDIPLLPHHKNYQLVSDISDSLIHFQKIPTIICWG
MKDFVFDKHFLNTWKEKMPHAVVHEFDDCGHYILEDASEQVIPLIETFMAENP
>Mature_293_residues
MNLDTLFPFKRNYLDRNGQQYHYLNEGSGEPVVMVHGNPSWSFYYRNLVKSLSRNYQCVVPDHIGCGLSDKPADKDYQYT
LKNRIDDLEALLDSLNINENITLVVHDWGGMIGMGYAARHPERIKRLVILNTAAFHLPSTKSFPVPLLIGRNTYIGTVLI
RGLNAFSAIASYVGVKRKPMEKAVRQAYVAPFNSWKNRISTLRFVQDIPLLPHHKNYQLVSDISDSLIHFQKIPTIICWG
MKDFVFDKHFLNTWKEKMPHAVVHEFDDCGHYILEDASEQVIPLIETFMAENP

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Has a broad substrate specificity, which includes mono- and di- chlorinated

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=308, Percent_Identity=23.7012987012987, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554012, Length=121, Percent_Identity=30.5785123966942, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562298, Length=295, Percent_Identity=23.728813559322, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 33696; Mature: 33696

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDTLFPFKRNYLDRNGQQYHYLNEGSGEPVVMVHGNPSWSFYYRNLVKSLSRNYQCVV
CCCCCCCCHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEE
PDHIGCGLSDKPADKDYQYTLKNRIDDLEALLDSLNINENITLVVHDWGGMIGMGYAARH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEECCHHHCC
PERIKRLVILNTAAFHLPSTKSFPVPLLIGRNTYIGTVLIRGLNAFSAIASYVGVKRKPM
HHHHHHHHEEEHHHEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
EKAVRQAYVAPFNSWKNRISTLRFVQDIPLLPHHKNYQLVSDISDSLIHFQKIPTIICWG
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEC
MKDFVFDKHFLNTWKEKMPHAVVHEFDDCGHYILEDASEQVIPLIETFMAENP
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLDTLFPFKRNYLDRNGQQYHYLNEGSGEPVVMVHGNPSWSFYYRNLVKSLSRNYQCVV
CCCCCCCCHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEE
PDHIGCGLSDKPADKDYQYTLKNRIDDLEALLDSLNINENITLVVHDWGGMIGMGYAARH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEECCHHHCC
PERIKRLVILNTAAFHLPSTKSFPVPLLIGRNTYIGTVLIRGLNAFSAIASYVGVKRKPM
HHHHHHHHEEEHHHEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
EKAVRQAYVAPFNSWKNRISTLRFVQDIPLLPHHKNYQLVSDISDSLIHFQKIPTIICWG
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEC
MKDFVFDKHFLNTWKEKMPHAVVHEFDDCGHYILEDASEQVIPLIETFMAENP
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094681; 10735862 [H]