Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 119945237

GI number: 119945237

Start: 1851055

End: 1852332

Strand: Reverse

Name: csd [H]

Synonym: Ping_1505

Alternate gene names: 119945237

Gene position: 1852332-1851055 (Counterclockwise)

Preceding gene: 119945238

Following gene: 119945236

Centisome position: 40.62

GC content: 44.37

Gene sequence:

>1278_bases
ATGTCCTTAGTCGACCGACCAGCAGAGCATGGCAGTTTGCCATTAAACAAGGTTGATTGGCCGGCAATTCGGCGTGATTT
TCCTCTGTTAGCACAAAAACCGTATAATAAACCCTTAGCTTATCTCGATAATGCCGCAACGACGCAAAAACCCAATAGTG
TGATTGATAGTATCGCGCACTTTTATCGTTTTGATAATGCCAATGTTCATCGTGGTATTTATCAATTAAGTGAGCGGGCT
ACTGCCACTTTTGAGGCAGCAAGGGATAAAATACAGTGTTTTTTAAATGCCAGGTTGCGAGAGGAAATTATTTTCGTCCG
CGGTGCGACTGAGGCTATTAATCTGGTCGCACAGAGTTATGCCCGGCCCCGCTTCAAATCAGGAGATGAGATCTTGATCA
GTGCGATAGAGCATCATTCCAATATAGTTCCCTGGCAAATGGTCTGCAAACAAACCGGCGCACAGCTAAAGGTTATACCA
ATCAATGATAACGGGGAGATTATGCTGGATAGTTATCAGGCATTATTAAGTGAAAAAACTAAAATAGTGGCAATCACCCA
TCTCTCCAATGCTTTGGGGAGTATTGCACCGGTGCAGCGAATGATAACCATGGCGCATGCTAGAGGAATACCGGTATTAC
TTGATGGTGCTCAAGCAGCCCCTCATCTCAGGATCAATCTGCAGGCTTTAGATTGTGAATTCTACACCTTTTCCAGTCAC
AAAATTTACGGCCCTACCGGAGTCGGCGTGTTATATGGCAAAAAAAGCTACCTTGATGCAATGGAGCCCTATCAGGGAGG
TGGGGAAATGATCAGTCGAGTCAGTTTTGAGAGCAGTGACTATAACGGCTTACCTTACAAATTTGAGGCAGGTACACCTA
ATATTGCGGGTGTGGTAGGTCTGGCTGCTGCCCTCGATTACATCAACACGATAGGTCTTGACAATATTTGCCAACGCGAA
CAACAGTTATTAGATTATGCCACCAAAGCATTAGAGCAAACAGCCGGGTTACGTATTATTGGCCAAGCAAAACACAAGGC
CAGTATTATCTCTTTTGTGCTTGATAGCGCGCATCCTCATGATATAAGTACAATTCTTGATCAGCAGGGAGTCGCAATTC
GAGCAGGTCATCACTGTGCGATGCCGGTGATGACCCGTTTTAATGTCCCGGCAACCGCACGCGCTTCCTTTTCTTTCTAC
AATAATGAAAGTGATATAGAACAATTAGTGCAAAGTTTGCGGCTGGTAAACAAAATTTTTACCATAAAAAATGGGTGA

Upstream 100 bases:

>100_bases
ACTTTATTCAGCTGTCCATCAGTGCACAACTTAAGCAGTTGGTGGGTAATGATGCCGGCAACTTAGCGCTGTTTCCCCCA
ATGGAAAATGGTGAGATGTT

Downstream 100 bases:

>100_bases
ATAAGATGAATGATGAACTACGCGCATTGTATCAGGAAGTGATCATTGACCATGGCCGCCGTCCGAGAAATTCCAAAAAG
CTTGAGCATCCGAGTTGCAC

Product: cysteine desulfurases, SufS subfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSLVDRPAEHGSLPLNKVDWPAIRRDFPLLAQKPYNKPLAYLDNAATTQKPNSVIDSIAHFYRFDNANVHRGIYQLSERA
TATFEAARDKIQCFLNARLREEIIFVRGATEAINLVAQSYARPRFKSGDEILISAIEHHSNIVPWQMVCKQTGAQLKVIP
INDNGEIMLDSYQALLSEKTKIVAITHLSNALGSIAPVQRMITMAHARGIPVLLDGAQAAPHLRINLQALDCEFYTFSSH
KIYGPTGVGVLYGKKSYLDAMEPYQGGGEMISRVSFESSDYNGLPYKFEAGTPNIAGVVGLAAALDYINTIGLDNICQRE
QQLLDYATKALEQTAGLRIIGQAKHKASIISFVLDSAHPHDISTILDQQGVAIRAGHHCAMPVMTRFNVPATARASFSFY
NNESDIEQLVQSLRLVNKIFTIKNG

Sequences:

>Translated_425_residues
MSLVDRPAEHGSLPLNKVDWPAIRRDFPLLAQKPYNKPLAYLDNAATTQKPNSVIDSIAHFYRFDNANVHRGIYQLSERA
TATFEAARDKIQCFLNARLREEIIFVRGATEAINLVAQSYARPRFKSGDEILISAIEHHSNIVPWQMVCKQTGAQLKVIP
INDNGEIMLDSYQALLSEKTKIVAITHLSNALGSIAPVQRMITMAHARGIPVLLDGAQAAPHLRINLQALDCEFYTFSSH
KIYGPTGVGVLYGKKSYLDAMEPYQGGGEMISRVSFESSDYNGLPYKFEAGTPNIAGVVGLAAALDYINTIGLDNICQRE
QQLLDYATKALEQTAGLRIIGQAKHKASIISFVLDSAHPHDISTILDQQGVAIRAGHHCAMPVMTRFNVPATARASFSFY
NNESDIEQLVQSLRLVNKIFTIKNG
>Mature_424_residues
SLVDRPAEHGSLPLNKVDWPAIRRDFPLLAQKPYNKPLAYLDNAATTQKPNSVIDSIAHFYRFDNANVHRGIYQLSERAT
ATFEAARDKIQCFLNARLREEIIFVRGATEAINLVAQSYARPRFKSGDEILISAIEHHSNIVPWQMVCKQTGAQLKVIPI
NDNGEIMLDSYQALLSEKTKIVAITHLSNALGSIAPVQRMITMAHARGIPVLLDGAQAAPHLRINLQALDCEFYTFSSHK
IYGPTGVGVLYGKKSYLDAMEPYQGGGEMISRVSFESSDYNGLPYKFEAGTPNIAGVVGLAAALDYINTIGLDNICQREQ
QLLDYATKALEQTAGLRIIGQAKHKASIISFVLDSAHPHDISTILDQQGVAIRAGHHCAMPVMTRFNVPATARASFSFYN
NESDIEQLVQSLRLVNKIFTIKNG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=300, Percent_Identity=26.3333333333333, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI156713448, Length=331, Percent_Identity=24.773413897281, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787970, Length=399, Percent_Identity=48.6215538847118, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1789175, Length=373, Percent_Identity=43.1635388739946, Blast_Score=338, Evalue=4e-94,
Organism=Escherichia coli, GI48994898, Length=233, Percent_Identity=30.9012875536481, Blast_Score=101, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI25143064, Length=228, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193211090, Length=379, Percent_Identity=28.7598944591029, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319831, Length=228, Percent_Identity=28.5087719298246, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI20129463, Length=361, Percent_Identity=25.7617728531856, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 46936; Mature: 46805

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVDRPAEHGSLPLNKVDWPAIRRDFPLLAQKPYNKPLAYLDNAATTQKPNSVIDSIAH
CCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHH
FYRFDNANVHRGIYQLSERATATFEAARDKIQCFLNARLREEIIFVRGATEAINLVAQSY
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHH
ARPRFKSGDEILISAIEHHSNIVPWQMVCKQTGAQLKVIPINDNGEIMLDSYQALLSEKT
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEECCCCCEEEHHHHHHHCCCC
KIVAITHLSNALGSIAPVQRMITMAHARGIPVLLDGAQAAPHLRINLQALDCEFYTFSSH
EEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEEEEEEEECCC
KIYGPTGVGVLYGKKSYLDAMEPYQGGGEMISRVSFESSDYNGLPYKFEAGTPNIAGVVG
EEECCCCCEEEECCHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHH
LAAALDYINTIGLDNICQREQQLLDYATKALEQTAGLRIIGQAKHKASIISFVLDSAHPH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCC
DISTILDQQGVAIRAGHHCAMPVMTRFNVPATARASFSFYNNESDIEQLVQSLRLVNKIF
HHHHHHCCCCCEEECCCCCCCCHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
TIKNG
HCCCC
>Mature Secondary Structure 
SLVDRPAEHGSLPLNKVDWPAIRRDFPLLAQKPYNKPLAYLDNAATTQKPNSVIDSIAH
CCCCCCCCCCCCCCCCCCCHHHHCCCCHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHH
FYRFDNANVHRGIYQLSERATATFEAARDKIQCFLNARLREEIIFVRGATEAINLVAQSY
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHH
ARPRFKSGDEILISAIEHHSNIVPWQMVCKQTGAQLKVIPINDNGEIMLDSYQALLSEKT
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEECCCCCEEEHHHHHHHCCCC
KIVAITHLSNALGSIAPVQRMITMAHARGIPVLLDGAQAAPHLRINLQALDCEFYTFSSH
EEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEEEEEEEECCC
KIYGPTGVGVLYGKKSYLDAMEPYQGGGEMISRVSFESSDYNGLPYKFEAGTPNIAGVVG
EEECCCCCEEEECCHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHH
LAAALDYINTIGLDNICQREQQLLDYATKALEQTAGLRIIGQAKHKASIISFVLDSAHPH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCC
DISTILDQQGVAIRAGHHCAMPVMTRFNVPATARASFSFYNNESDIEQLVQSLRLVNKIF
HHHHHHCCCCCEEECCCCCCCCHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
TIKNG
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]