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The map label for this gene is yfbQ [H]

Identifier: 119945211

GI number: 119945211

Start: 1823709

End: 1824923

Strand: Reverse

Name: yfbQ [H]

Synonym: Ping_1475

Alternate gene names: 119945211

Gene position: 1824923-1823709 (Counterclockwise)

Preceding gene: 119945216

Following gene: 119945208

Centisome position: 40.02

GC content: 41.89

Gene sequence:

>1215_bases
ATGTATACCATTCAAAAGTCCACTAAATTAGATAATGTCTGTTATGACATTCGCGGACCCGTCCTTAAACAAGCGCATAA
ATTGGAGGAAGAAGGACAGCGTATTTTAAAACTAAATATCGGTAATCCTGCCCAATTTGGCTTTGATGCACCTGAAGAAG
TGATGATGGATGTGATAAAAAACCTGCCGCAAAGTCAGGGGTATTGTGACAGCAAAGGCCTTTTTTCCGCCCGTAAATCG
GTTATGCAGCATTATCAGGCGAAAGGTTTACTGTCACTTGATACCCATGATATTTATATTGGCAACGGAGTCAGTGAATT
AATTGTAATGGCGATGCAGGGTTTATTAAATAATGGTGATGAGCTATTGGTACCTGCACCGGATTACCCGCTATGGACAG
CCGCAACAAATTTATCCGGCGGGAAAGCGGTCCATTATATTTGTGATGAACAGTCAGATTGGTTTCCCGATATCGAGGAT
ATTAAATCTAAAATAACCGTCAAAACCAAAGGGATTGTTATTATCAATCCCAATAATCCCACCGGCGCGGTTTACAGCAG
GGAGTTATTAGAGCAGATTATAGAGCTTGCCCGTATCCACAATTTAATTGTCTTTTCCGACGAAATCTATTCGAAAATAA
TTTACGATGATGCGGTGCATATTCCACTCGCAACCCTCGCTGACGATATTTTAATTGTGACCTTTGATGGACTATCTAAA
GCCTATCGGGTTTGCGGTTTTCGCGTCGGTTGGATGATGATAAGCGGCGCAAAAAAGCAAGCGCGTGATTATATTAATGG
ATTAGAGATGCTCGCCAGTATGCGTTTATGCGCCAATGTGCCGATGCAGCATGCTATCCAAACTTCCCTTGGCGGGTATC
AAAGTATTAATGAGTTAACCGTCCCAGGCGGACGTTTATATGAACAAACTCAAAGTGCATGGAAGTTAATTAATGATATT
CCCGGGTTAAGCTGTACTAAACCTAAGGGCGCTTTATACCTTTTCCCTAAACTGGATCAAAAGAAATTTAACATTAAAGA
CGATCAGCGGTTTGCCATGGATCTGTTGATGGAAGAAAAAATATTAATTGTACAGGGGACGGGCTTTAACTGGCACTCAC
CGGATCACTTCCGTATTGTTTGTTTGCCGCGTGTTGATGAACTCAGTACTGCTATCTCGAAAATAGGCCGTTTTCTGCAA
AGTTATCGCCAGTAG

Upstream 100 bases:

>100_bases
TCTTTGTTATTTGCTTCACAGCGTCTTCAATATCAGGTACGTTTGACAGTAAAAAATAACTTTTCTTTACTTACCAAAAT
TTATGCATTAAGAGGTGCTC

Downstream 100 bases:

>100_bases
AGTTAAAATGAATCAATAAAGTCTAAAATGGTGACAAACAGTCGCTATTTTAGATTTTATTCAATAATTTATATCTGCTA
ATTGTCCTTATCTTTATACA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MYTIQKSTKLDNVCYDIRGPVLKQAHKLEEEGQRILKLNIGNPAQFGFDAPEEVMMDVIKNLPQSQGYCDSKGLFSARKS
VMQHYQAKGLLSLDTHDIYIGNGVSELIVMAMQGLLNNGDELLVPAPDYPLWTAATNLSGGKAVHYICDEQSDWFPDIED
IKSKITVKTKGIVIINPNNPTGAVYSRELLEQIIELARIHNLIVFSDEIYSKIIYDDAVHIPLATLADDILIVTFDGLSK
AYRVCGFRVGWMMISGAKKQARDYINGLEMLASMRLCANVPMQHAIQTSLGGYQSINELTVPGGRLYEQTQSAWKLINDI
PGLSCTKPKGALYLFPKLDQKKFNIKDDQRFAMDLLMEEKILIVQGTGFNWHSPDHFRIVCLPRVDELSTAISKIGRFLQ
SYRQ

Sequences:

>Translated_404_residues
MYTIQKSTKLDNVCYDIRGPVLKQAHKLEEEGQRILKLNIGNPAQFGFDAPEEVMMDVIKNLPQSQGYCDSKGLFSARKS
VMQHYQAKGLLSLDTHDIYIGNGVSELIVMAMQGLLNNGDELLVPAPDYPLWTAATNLSGGKAVHYICDEQSDWFPDIED
IKSKITVKTKGIVIINPNNPTGAVYSRELLEQIIELARIHNLIVFSDEIYSKIIYDDAVHIPLATLADDILIVTFDGLSK
AYRVCGFRVGWMMISGAKKQARDYINGLEMLASMRLCANVPMQHAIQTSLGGYQSINELTVPGGRLYEQTQSAWKLINDI
PGLSCTKPKGALYLFPKLDQKKFNIKDDQRFAMDLLMEEKILIVQGTGFNWHSPDHFRIVCLPRVDELSTAISKIGRFLQ
SYRQ
>Mature_404_residues
MYTIQKSTKLDNVCYDIRGPVLKQAHKLEEEGQRILKLNIGNPAQFGFDAPEEVMMDVIKNLPQSQGYCDSKGLFSARKS
VMQHYQAKGLLSLDTHDIYIGNGVSELIVMAMQGLLNNGDELLVPAPDYPLWTAATNLSGGKAVHYICDEQSDWFPDIED
IKSKITVKTKGIVIINPNNPTGAVYSRELLEQIIELARIHNLIVFSDEIYSKIIYDDAVHIPLATLADDILIVTFDGLSK
AYRVCGFRVGWMMISGAKKQARDYINGLEMLASMRLCANVPMQHAIQTSLGGYQSINELTVPGGRLYEQTQSAWKLINDI
PGLSCTKPKGALYLFPKLDQKKFNIKDDQRFAMDLLMEEKILIVQGTGFNWHSPDHFRIVCLPRVDELSTAISKIGRFLQ
SYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=27.8645833333333, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI19263340, Length=462, Percent_Identity=25.974025974026, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=27.445652173913, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI4885351, Length=451, Percent_Identity=24.390243902439, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI95147551, Length=157, Percent_Identity=29.9363057324841, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI169881279, Length=157, Percent_Identity=29.9363057324841, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI56713254, Length=165, Percent_Identity=28.4848484848485, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI56713256, Length=165, Percent_Identity=28.4848484848485, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI169881281, Length=143, Percent_Identity=28.6713286713287, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI187936925, Length=376, Percent_Identity=22.6063829787234, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14211921, Length=376, Percent_Identity=22.6063829787234, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=70.5445544554455, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=385, Percent_Identity=24.9350649350649, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1786816, Length=255, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787909, Length=293, Percent_Identity=23.2081911262799, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=27.7777777777778, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71981209, Length=460, Percent_Identity=25.8695652173913, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=163, Percent_Identity=32.5153374233129, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=163, Percent_Identity=32.5153374233129, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=25.938566552901, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=166, Percent_Identity=31.3253012048193, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=450, Percent_Identity=25.1111111111111, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=436, Percent_Identity=26.605504587156, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322401, Length=351, Percent_Identity=24.7863247863248, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=25.5263157894737, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24641770, Length=493, Percent_Identity=25.3549695740365, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24641760, Length=493, Percent_Identity=25.3549695740365, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24641768, Length=493, Percent_Identity=25.3549695740365, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24641766, Length=493, Percent_Identity=25.3549695740365, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24641764, Length=493, Percent_Identity=25.3549695740365, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI45551451, Length=493, Percent_Identity=25.3549695740365, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI28573069, Length=164, Percent_Identity=29.8780487804878, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646114, Length=164, Percent_Identity=29.8780487804878, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573067, Length=164, Percent_Identity=29.8780487804878, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573065, Length=164, Percent_Identity=29.8780487804878, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45380; Mature: 45380

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTIQKSTKLDNVCYDIRGPVLKQAHKLEEEGQRILKLNIGNPAQFGFDAPEEVMMDVIK
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPQSQGYCDSKGLFSARKSVMQHYQAKGLLSLDTHDIYIGNGVSELIVMAMQGLLNNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHHHCCCC
ELLVPAPDYPLWTAATNLSGGKAVHYICDEQSDWFPDIEDIKSKITVKTKGIVIINPNNP
EEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHCEEEEEECCEEEECCCCC
TGAVYSRELLEQIIELARIHNLIVFSDEIYSKIIYDDAVHIPLATLADDILIVTFDGLSK
CCHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCHHH
AYRVCGFRVGWMMISGAKKQARDYINGLEMLASMRLCANVPMQHAIQTSLGGYQSINELT
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEE
VPGGRLYEQTQSAWKLINDIPGLSCTKPKGALYLFPKLDQKKFNIKDDQRFAMDLLMEEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCC
ILIVQGTGFNWHSPDHFRIVCLPRVDELSTAISKIGRFLQSYRQ
EEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYTIQKSTKLDNVCYDIRGPVLKQAHKLEEEGQRILKLNIGNPAQFGFDAPEEVMMDVIK
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPQSQGYCDSKGLFSARKSVMQHYQAKGLLSLDTHDIYIGNGVSELIVMAMQGLLNNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHHHCCCC
ELLVPAPDYPLWTAATNLSGGKAVHYICDEQSDWFPDIEDIKSKITVKTKGIVIINPNNP
EEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHCEEEEEECCEEEECCCCC
TGAVYSRELLEQIIELARIHNLIVFSDEIYSKIIYDDAVHIPLATLADDILIVTFDGLSK
CCHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCHHH
AYRVCGFRVGWMMISGAKKQARDYINGLEMLASMRLCANVPMQHAIQTSLGGYQSINELT
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEE
VPGGRLYEQTQSAWKLINDIPGLSCTKPKGALYLFPKLDQKKFNIKDDQRFAMDLLMEEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCC
ILIVQGTGFNWHSPDHFRIVCLPRVDELSTAISKIGRFLQSYRQ
EEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]