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The map label for this gene is pdxH

Identifier: 119945216

GI number: 119945216

Start: 1830906

End: 1831559

Strand: Reverse

Name: pdxH

Synonym: Ping_1481

Alternate gene names: 119945216

Gene position: 1831559-1830906 (Counterclockwise)

Preceding gene: 119945219

Following gene: 119945211

Centisome position: 40.17

GC content: 42.35

Gene sequence:

>654_bases
ATGTCATTTATCAGTAAAATTCGTTGTGCTTTCACCCTAGGTCAAGGTGTATTAATCGAAAATGAAGCATTAAAAGAAAC
CAATGACCCCATTTTATTTTTTAATAACTGGTTAAAAAAAGCGCAAGATACCGGTATTATCCTGCCTGAATCTATGTCCA
TTTCAACTTGTACGCCGGAAGGACGCCCCTCTTCCCGCATGGTATTATTAAAAGAAGTCGATTCTAAAGGTTTTGTTTTT
TTCACCAATTATGATAGTCGTAAAGCCCATGATCTCGAGGCCAACCCATTTGCAGCACTCTTATTTCACTGGAATATACT
GCAACGTCAAGTACGTATTGAGGGGAGAGTTGAGCGGATCAGCACTGCGCAATCAAATGCCTATTTTCAAAGTCGTGGCC
GGGGCAGCCGCATTGGTGCCTGGGCCTCACATCAAAGCCAGGAGCTTAATGATCGGCAGACCTTAGTAGAAAGAGTAAAA
TATTTTGAAGAAAAATTTGCCGGAAAAGAAATTCCATTACCCGAATTTTGGGGGGGCTATCGGGTTATCCCTGAAAGCAT
CGAGTTTTGGCAGGGCAAAGCGGATCGTTTGCATGACAGATTTGTCTATCAACCGACGGAAAAAAACTGGACAGTGAAAC
GCCTAAACCCTTAA

Upstream 100 bases:

>100_bases
TAGCATAGGTTGAATTATTCGACAAAATTTGTAACAAATTATACACTCAGGAGGCAGCTTGGGTATACCCTTTAAATTTC
AATTTAAATAAGAAGATATT

Downstream 100 bases:

>100_bases
ACCTAAAGCCGACAGCTAACAGCCGACAGCCGACAGCCGACAGATTTTCCCATATCTGCCGCATTATTTTAAAATAATAC
GCGCATTGGTCGCTTGAATA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSFISKIRCAFTLGQGVLIENEALKETNDPILFFNNWLKKAQDTGIILPESMSISTCTPEGRPSSRMVLLKEVDSKGFVF
FTNYDSRKAHDLEANPFAALLFHWNILQRQVRIEGRVERISTAQSNAYFQSRGRGSRIGAWASHQSQELNDRQTLVERVK
YFEEKFAGKEIPLPEFWGGYRVIPESIEFWQGKADRLHDRFVYQPTEKNWTVKRLNP

Sequences:

>Translated_217_residues
MSFISKIRCAFTLGQGVLIENEALKETNDPILFFNNWLKKAQDTGIILPESMSISTCTPEGRPSSRMVLLKEVDSKGFVF
FTNYDSRKAHDLEANPFAALLFHWNILQRQVRIEGRVERISTAQSNAYFQSRGRGSRIGAWASHQSQELNDRQTLVERVK
YFEEKFAGKEIPLPEFWGGYRVIPESIEFWQGKADRLHDRFVYQPTEKNWTVKRLNP
>Mature_216_residues
SFISKIRCAFTLGQGVLIENEALKETNDPILFFNNWLKKAQDTGIILPESMSISTCTPEGRPSSRMVLLKEVDSKGFVFF
TNYDSRKAHDLEANPFAALLFHWNILQRQVRIEGRVERISTAQSNAYFQSRGRGSRIGAWASHQSQELNDRQTLVERVKY
FEEKFAGKEIPLPEFWGGYRVIPESIEFWQGKADRLHDRFVYQPTEKNWTVKRLNP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family

Homologues:

Organism=Homo sapiens, GI8922498, Length=218, Percent_Identity=41.2844036697248, Blast_Score=175, Evalue=2e-44,
Organism=Escherichia coli, GI1787926, Length=189, Percent_Identity=47.6190476190476, Blast_Score=190, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17553712, Length=197, Percent_Identity=43.1472081218274, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319509, Length=197, Percent_Identity=48.2233502538071, Blast_Score=185, Evalue=6e-48,
Organism=Drosophila melanogaster, GI45551845, Length=232, Percent_Identity=41.8103448275862, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24644901, Length=232, Percent_Identity=41.8103448275862, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24644903, Length=196, Percent_Identity=31.6326530612245, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXH_PSYIN (A1SUY2)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942896.1
- ProteinModelPortal:   A1SUY2
- SMR:   A1SUY2
- STRING:   A1SUY2
- GeneID:   4625821
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1481
- eggNOG:   COG0259
- HOGENOM:   HBG327559
- OMA:   FTFFTNY
- PhylomeDB:   A1SUY2
- ProtClustDB:   CLSK768225
- BioCyc:   PING357804:PING_1481-MONOMER
- HAMAP:   MF_01629
- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002
- Gene3D:   G3DSA:2.30.110.10
- PANTHER:   PTHR10851
- PIRSF:   PIRSF000190
- TIGRFAMs:   TIGR00558

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase; SSF50475 FMN_binding

EC number: =1.4.3.5

Molecular weight: Translated: 25178; Mature: 25047

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: BINDING 66-66 BINDING 69-69 BINDING 71-71 BINDING 88-88 BINDING 128-128 BINDING 132-132 BINDING 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFISKIRCAFTLGQGVLIENEALKETNDPILFFNNWLKKAQDTGIILPESMSISTCTPE
CCHHHHHHHEEEECCCEEEECHHHHCCCCCEEEECHHHHHHCCCCEECCCCCCEEECCCC
GRPSSRMVLLKEVDSKGFVFFTNYDSRKAHDLEANPFAALLFHWNILQRQVRIEGRVERI
CCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
STAQSNAYFQSRGRGSRIGAWASHQSQELNDRQTLVERVKYFEEKFAGKEIPLPEFWGGY
HHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
RVIPESIEFWQGKADRLHDRFVYQPTEKNWTVKRLNP
EECCCHHHHHCCCHHHHHHHEEECCCCCCEEEEECCC
>Mature Secondary Structure 
SFISKIRCAFTLGQGVLIENEALKETNDPILFFNNWLKKAQDTGIILPESMSISTCTPE
CHHHHHHHEEEECCCEEEECHHHHCCCCCEEEECHHHHHHCCCCEECCCCCCEEECCCC
GRPSSRMVLLKEVDSKGFVFFTNYDSRKAHDLEANPFAALLFHWNILQRQVRIEGRVERI
CCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
STAQSNAYFQSRGRGSRIGAWASHQSQELNDRQTLVERVKYFEEKFAGKEIPLPEFWGGY
HHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
RVIPESIEFWQGKADRLHDRFVYQPTEKNWTVKRLNP
EECCCHHHHHCCCHHHHHHHEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA