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The map label for this gene is purN [H]

Identifier: 119944826

GI number: 119944826

Start: 1342232

End: 1342894

Strand: Reverse

Name: purN [H]

Synonym: Ping_1068

Alternate gene names: 119944826

Gene position: 1342894-1342232 (Counterclockwise)

Preceding gene: 119944827

Following gene: 119944823

Centisome position: 29.45

GC content: 39.67

Gene sequence:

>663_bases
ATGGCAACTGTAGCAACTAAAAAAATTGTCGTTCTGCTCTCTGGTAACGGTAGTAACCTGCAAAATATTATTGACAAGCT
TCATAATACAACGCTTAACAATCAACATATCGAAATTGTTGCTGTGTTAAGCAACAAAGCCGATGCCTATGGTTTACAGC
GCGCTCAGAATGCGGGTATTAAGCATAAGGCGATTATCAGTAAGGGGATTAGTTCACGCGAGCAATATGATGCTTTATTA
AGCCAAGAAATTGATCAATATCAACCCGACTTGATTGTTATGGCGGGTTTTATGCGCATATTGTCAGCGCAATTTATTGA
TAAATATCCAGGCAAGATGCTCAATATTCACCCCTCTTTATTACCTAAGTATCAGGGTACAAATACGCATCAAAGAGCGA
TAGATGCAGGTGACTCAGAGCATGGAGTAAGCGTTCATTTTGTGACAGAAGAATTAGATTCTGGCGCAACGGTGATACAA
GCTAAAGTGCCTATTTTCAGTGAAGATAGCGCTGAAAAGCTGGCCGAGCGAGTATTAACTCAAGAACACTTAATCTACCC
TTTAGCCATACAATGGTTTTTATCCGGTCGTTTAAGTATGGTAAATAGTCATGCACTATTAGATGGTTTGATCTTGCCTG
CTAATGGTTATGCTGCTGATTAA

Upstream 100 bases:

>100_bases
AGTTGAAATATTAACTGCTCAAGGTGAAAATGCCTGGGTACTTGGTCATATCGAAGACGCCGCAGCAGATGAAGCACAAG
TCGAGATTAACTAAACAATT

Downstream 100 bases:

>100_bases
TTTTATATATAAGCAAACTACTTGAAGATCCGGACTCCTGCACCTTAAAGTAGTTGGGTATAATACAAGCTCAGAAAACC
GAAGTTAATCTTCGGTTTTT

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MATVATKKIVVLLSGNGSNLQNIIDKLHNTTLNNQHIEIVAVLSNKADAYGLQRAQNAGIKHKAIISKGISSREQYDALL
SQEIDQYQPDLIVMAGFMRILSAQFIDKYPGKMLNIHPSLLPKYQGTNTHQRAIDAGDSEHGVSVHFVTEELDSGATVIQ
AKVPIFSEDSAEKLAERVLTQEHLIYPLAIQWFLSGRLSMVNSHALLDGLILPANGYAAD

Sequences:

>Translated_220_residues
MATVATKKIVVLLSGNGSNLQNIIDKLHNTTLNNQHIEIVAVLSNKADAYGLQRAQNAGIKHKAIISKGISSREQYDALL
SQEIDQYQPDLIVMAGFMRILSAQFIDKYPGKMLNIHPSLLPKYQGTNTHQRAIDAGDSEHGVSVHFVTEELDSGATVIQ
AKVPIFSEDSAEKLAERVLTQEHLIYPLAIQWFLSGRLSMVNSHALLDGLILPANGYAAD
>Mature_219_residues
ATVATKKIVVLLSGNGSNLQNIIDKLHNTTLNNQHIEIVAVLSNKADAYGLQRAQNAGIKHKAIISKGISSREQYDALLS
QEIDQYQPDLIVMAGFMRILSAQFIDKYPGKMLNIHPSLLPKYQGTNTHQRAIDAGDSEHGVSVHFVTEELDSGATVIQA
KVPIFSEDSAEKLAERVLTQEHLIYPLAIQWFLSGRLSMVNSHALLDGLILPANGYAAD

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=193, Percent_Identity=41.9689119170984, Blast_Score=167, Evalue=6e-42,
Organism=Homo sapiens, GI209869995, Length=193, Percent_Identity=41.9689119170984, Blast_Score=167, Evalue=6e-42,
Organism=Homo sapiens, GI209869993, Length=193, Percent_Identity=41.9689119170984, Blast_Score=167, Evalue=6e-42,
Organism=Escherichia coli, GI1788846, Length=212, Percent_Identity=57.0754716981132, Blast_Score=251, Evalue=4e-68,
Organism=Escherichia coli, GI1787483, Length=201, Percent_Identity=26.865671641791, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567511, Length=183, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320616, Length=199, Percent_Identity=33.6683417085427, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582400, Length=190, Percent_Identity=44.7368421052632, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 24097; Mature: 23966

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVATKKIVVLLSGNGSNLQNIIDKLHNTTLNNQHIEIVAVLSNKADAYGLQRAQNAGI
CCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCC
KHKAIISKGISSREQYDALLSQEIDQYQPDLIVMAGFMRILSAQFIDKYPGKMLNIHPSL
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHH
LPKYQGTNTHQRAIDAGDSEHGVSVHFVTEELDSGATVIQAKVPIFSEDSAEKLAERVLT
CCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
QEHLIYPLAIQWFLSGRLSMVNSHALLDGLILPANGYAAD
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCEEECCCCCCCC
>Mature Secondary Structure 
ATVATKKIVVLLSGNGSNLQNIIDKLHNTTLNNQHIEIVAVLSNKADAYGLQRAQNAGI
CCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCC
KHKAIISKGISSREQYDALLSQEIDQYQPDLIVMAGFMRILSAQFIDKYPGKMLNIHPSL
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHH
LPKYQGTNTHQRAIDAGDSEHGVSVHFVTEELDSGATVIQAKVPIFSEDSAEKLAERVLT
CCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
QEHLIYPLAIQWFLSGRLSMVNSHALLDGLILPANGYAAD
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]