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The map label for this gene is murQ

Identifier: 119944823

GI number: 119944823

Start: 1340012

End: 1340911

Strand: Reverse

Name: murQ

Synonym: Ping_1065

Alternate gene names: 119944823

Gene position: 1340911-1340012 (Counterclockwise)

Preceding gene: 119944826

Following gene: 119944818

Centisome position: 29.41

GC content: 44.11

Gene sequence:

>900_bases
ATGTCAGCACCTCCAGAAAATTTAATGACCGAGAGCCGCAATCCCGCAAGCAGTCACATTGATACGCTATCGACCCTTGA
AATGCTTAAAGTGATGAATGCAGAAGACAAAAAAGTTGCATTGGCGGTGGAATTGGCGCTTCCTTCGATTACCCAAGCGG
TTGATTTAATTAGTGCAGCTTTTCATAAAAAGGGACGACTAATTTATTGTGGTGCGGGCACCTCGGGCCGTTTGGGTATA
CTAGATGCCAGTGAATGCCCACCAACTTTTGGAACACCGGCGAAGCAGGTAATGGCTTTAATTGCGGGCGGTCATCGGGC
GATATTAAAAGCTGTAGAAAACGCAGAAGATAATCTGCAAGCGGGTCAGTCTGATTTACAAAATATCAACTTTAATGAAA
ACGATATTTTAGTGGGCATAGCAGCCAGTGGCTCTACCCCCTATGTTATCGGCGCGATGCGCTATGCAAAATCGATTAAT
GCCCAGGTAATCGCTATTAACTGTAACCCCAACAGTCTGATGTCCAAGGAGTGTGATGTTAATATCTGTGCCGTAGTCGG
CCCTGAAGTGCTGACGGGTTCATCACGTTTAAAAGCCGGTACAGCTCAAAAATTAATTTTAAACATGCTTACCACCGGTG
CGATGATCCGTACCGGTAAAGTCTTTGGTAATTTAATGGTGGATGTTCAAGCGACAAACGCTAAGCTTGTCGAACGGCAA
AAAATGATCGTGATTGCAGCAACCGATTGCCTGCGGGAGGAAGCTGAAAAGGCCTTGCTGCAATGTAATGGCCACTGTAA
AACAGCCATTGTAATGATCTTAACCAATACAAATACCGCTCAGGCTAAATCATTATTAGCTAAAAATAACGGTTATATCC
GTCAATCGATCGTTAAATAA

Upstream 100 bases:

>100_bases
AGAAGATTTGTATATTATATCGAAAGACTGAATTGAAGGATAATAACTTTGTTTATCTGAATCAAAAAATTCACCTACTT
ATTAATTAAAGAGCATAAAA

Downstream 100 bases:

>100_bases
AGGGGTTTTAACCCCCACTATCAAAGGATTAGTATATCTTGAATTGAAGGGCTTATTTATCTTCGTAAATATTATCATAA
ACATAATTTGTAGCTTCAAT

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSAPPENLMTESRNPASSHIDTLSTLEMLKVMNAEDKKVALAVELALPSITQAVDLISAAFHKKGRLIYCGAGTSGRLGI
LDASECPPTFGTPAKQVMALIAGGHRAILKAVENAEDNLQAGQSDLQNINFNENDILVGIAASGSTPYVIGAMRYAKSIN
AQVIAINCNPNSLMSKECDVNICAVVGPEVLTGSSRLKAGTAQKLILNMLTTGAMIRTGKVFGNLMVDVQATNAKLVERQ
KMIVIAATDCLREEAEKALLQCNGHCKTAIVMILTNTNTAQAKSLLAKNNGYIRQSIVK

Sequences:

>Translated_299_residues
MSAPPENLMTESRNPASSHIDTLSTLEMLKVMNAEDKKVALAVELALPSITQAVDLISAAFHKKGRLIYCGAGTSGRLGI
LDASECPPTFGTPAKQVMALIAGGHRAILKAVENAEDNLQAGQSDLQNINFNENDILVGIAASGSTPYVIGAMRYAKSIN
AQVIAINCNPNSLMSKECDVNICAVVGPEVLTGSSRLKAGTAQKLILNMLTTGAMIRTGKVFGNLMVDVQATNAKLVERQ
KMIVIAATDCLREEAEKALLQCNGHCKTAIVMILTNTNTAQAKSLLAKNNGYIRQSIVK
>Mature_298_residues
SAPPENLMTESRNPASSHIDTLSTLEMLKVMNAEDKKVALAVELALPSITQAVDLISAAFHKKGRLIYCGAGTSGRLGIL
DASECPPTFGTPAKQVMALIAGGHRAILKAVENAEDNLQAGQSDLQNINFNENDILVGIAASGSTPYVIGAMRYAKSINA
QVIAINCNPNSLMSKECDVNICAVVGPEVLTGSSRLKAGTAQKLILNMLTTGAMIRTGKVFGNLMVDVQATNAKLVERQK
MIVIAATDCLREEAEKALLQCNGHCKTAIVMILTNTNTAQAKSLLAKNNGYIRQSIVK

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=294, Percent_Identity=57.1428571428571, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_PSYIN (A1STT9)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942503.1
- ProteinModelPortal:   A1STT9
- SMR:   A1STT9
- STRING:   A1STT9
- GeneID:   4625993
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1065
- eggNOG:   COG2103
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- PhylomeDB:   A1STT9
- ProtClustDB:   PRK05441
- BioCyc:   PING357804:PING_1065-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 31709; Mature: 31578

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 85-85 ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPPENLMTESRNPASSHIDTLSTLEMLKVMNAEDKKVALAVELALPSITQAVDLISAA
CCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
FHKKGRLIYCGAGTSGRLGILDASECPPTFGTPAKQVMALIAGGHRAILKAVENAEDNLQ
HHCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHH
AGQSDLQNINFNENDILVGIAASGSTPYVIGAMRYAKSINAQVIAINCNPNSLMSKECDV
CCHHHHHCCCCCCCCEEEEEECCCCCCEEEHHHHHHHCCCCEEEEEECCCCHHCCCCCCC
NICAVVGPEVLTGSSRLKAGTAQKLILNMLTTGAMIRTGKVFGNLMVDVQATNAKLVERQ
EEEEEECCHHHCCCCHHCCCHHHHHHHHHHHCCHHEEECCEEEEEEEEEEECCHHHHCCC
KMIVIAATDCLREEAEKALLQCNGHCKTAIVMILTNTNTAQAKSLLAKNNGYIRQSIVK
EEEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
SAPPENLMTESRNPASSHIDTLSTLEMLKVMNAEDKKVALAVELALPSITQAVDLISAA
CCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
FHKKGRLIYCGAGTSGRLGILDASECPPTFGTPAKQVMALIAGGHRAILKAVENAEDNLQ
HHCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHH
AGQSDLQNINFNENDILVGIAASGSTPYVIGAMRYAKSINAQVIAINCNPNSLMSKECDV
CCHHHHHCCCCCCCCEEEEEECCCCCCEEEHHHHHHHCCCCEEEEEECCCCHHCCCCCCC
NICAVVGPEVLTGSSRLKAGTAQKLILNMLTTGAMIRTGKVFGNLMVDVQATNAKLVERQ
EEEEEECCHHHCCCCHHCCCHHHHHHHHHHHCCHHEEECCEEEEEEEEEEECCHHHHCCC
KMIVIAATDCLREEAEKALLQCNGHCKTAIVMILTNTNTAQAKSLLAKNNGYIRQSIVK
EEEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA