Click here to switch to the map view.

The map label for this gene is pdxJ [H]

Identifier: 119944415

GI number: 119944415

Start: 827867

End: 828601

Strand: Direct

Name: pdxJ [H]

Synonym: Ping_0643

Alternate gene names: 119944415

Gene position: 827867-828601 (Clockwise)

Preceding gene: 119944414

Following gene: 119944416

Centisome position: 18.16

GC content: 46.53

Gene sequence:

>735_bases
ATGAGTCAAATTTTACTTGGCGTTAATATCGATCATATCGCAACATTACGTAACGCTCGTGGTACTTGTTATCCTGAGCC
TGCTCATTTAGCGGCTATTGCCGAGTGTGCCGGTGCCGATGGTATCACTATTCATCTGCGTGAAGATCGTCGCCATATTA
ATGATCGGGATGTCGCAGTACTTGCACAAACGCTGCAAACGCGGATGAACTTGGAAATGGCGGTAACCGATGAGATGGTC
GATATTGCGCTAAAAACAAAACCCGCCTTTGTGTGCCTGGTACCTGAAAAACGCGAAGAGCTAACCACTGAAGGTGGCTT
AAATGTGGTTGCTTCATTTTCTAAAATTGCCTCTGCCGTGAGCCGGTTAAATGCGGCCGCTATTCAGGTATCATTATTTA
TTGATCCTGAAAACGCGCAAATTGATGCTGCGATTAAAACCGGTGCCGCTTATATTGAGCTGCATACGGGGAAATATGCT
GATGCGCCGTCTGAAGATATTCAACAGTTTGAGTTAATGCGCGTCGCAAAAGCGGCAACTTATGCAAGCCAAGCGGGTAT
CAAAGTGAATGCCGGGCATGGTCTTAATTACCATAATGTGAAACCTATCGCAGCATTGCCTGAAATTATCGAGCTTAATA
TCGGGCATGCGATTGTGGCCCGTGCGCTTGTTGATGGTTTTGGACCTGCAGTTGCAGAAATGAAGCGTCTGATGGTTGAA
GGCCGTAACGGCTAA

Upstream 100 bases:

>100_bases
ACGATTTTGCCGGCAAGCATTAGCTAATCTCTTAGGTGGCAAACCATTACATAGTCGGGCACTCTTTACGGCTAAATAAA
CAATAAAGGATAATTTGTAA

Downstream 100 bases:

>100_bases
ATAATACCAAATCCATTAATTTTCTGTTCATTTATGCTGGTTAAAACACATACTAGCTAGACATAAAACTACGTTTTAGT
CTTTGTGCTTGATTTTATAA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSQILLGVNIDHIATLRNARGTCYPEPAHLAAIAECAGADGITIHLREDRRHINDRDVAVLAQTLQTRMNLEMAVTDEMV
DIALKTKPAFVCLVPEKREELTTEGGLNVVASFSKIASAVSRLNAAAIQVSLFIDPENAQIDAAIKTGAAYIELHTGKYA
DAPSEDIQQFELMRVAKAATYASQAGIKVNAGHGLNYHNVKPIAALPEIIELNIGHAIVARALVDGFGPAVAEMKRLMVE
GRNG

Sequences:

>Translated_244_residues
MSQILLGVNIDHIATLRNARGTCYPEPAHLAAIAECAGADGITIHLREDRRHINDRDVAVLAQTLQTRMNLEMAVTDEMV
DIALKTKPAFVCLVPEKREELTTEGGLNVVASFSKIASAVSRLNAAAIQVSLFIDPENAQIDAAIKTGAAYIELHTGKYA
DAPSEDIQQFELMRVAKAATYASQAGIKVNAGHGLNYHNVKPIAALPEIIELNIGHAIVARALVDGFGPAVAEMKRLMVE
GRNG
>Mature_243_residues
SQILLGVNIDHIATLRNARGTCYPEPAHLAAIAECAGADGITIHLREDRRHINDRDVAVLAQTLQTRMNLEMAVTDEMVD
IALKTKPAFVCLVPEKREELTTEGGLNVVASFSKIASAVSRLNAAAIQVSLFIDPENAQIDAAIKTGAAYIELHTGKYAD
APSEDIQQFELMRVAKAATYASQAGIKVNAGHGLNYHNVKPIAALPEIIELNIGHAIVARALVDGFGPAVAEMKRLMVEG
RNG

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=242, Percent_Identity=66.9421487603306, Blast_Score=328, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 26183; Mature: 26052

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQILLGVNIDHIATLRNARGTCYPEPAHLAAIAECAGADGITIHLREDRRHINDRDVAV
CCEEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHH
LAQTLQTRMNLEMAVTDEMVDIALKTKPAFVCLVPEKREELTTEGGLNVVASFSKIASAV
HHHHHHHHCCEEEEEHHHHHEEEEECCCEEEEECCCHHHHHCCCCCHHHHHHHHHHHHHH
SRLNAAAIQVSLFIDPENAQIDAAIKTGAAYIELHTGKYADAPSEDIQQFELMRVAKAAT
HHCCCEEEEEEEEECCCCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
YASQAGIKVNAGHGLNYHNVKPIAALPEIIELNIGHAIVARALVDGFGPAVAEMKRLMVE
HHHHCCEEEECCCCCCCCCCCCHHHCCHHHEECCCHHHHHHHHHHCCCHHHHHHHHHHHC
GRNG
CCCC
>Mature Secondary Structure 
SQILLGVNIDHIATLRNARGTCYPEPAHLAAIAECAGADGITIHLREDRRHINDRDVAV
CEEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHH
LAQTLQTRMNLEMAVTDEMVDIALKTKPAFVCLVPEKREELTTEGGLNVVASFSKIASAV
HHHHHHHHCCEEEEEHHHHHEEEEECCCEEEEECCCHHHHHCCCCCHHHHHHHHHHHHHH
SRLNAAAIQVSLFIDPENAQIDAAIKTGAAYIELHTGKYADAPSEDIQQFELMRVAKAAT
HHCCCEEEEEEEEECCCCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
YASQAGIKVNAGHGLNYHNVKPIAALPEIIELNIGHAIVARALVDGFGPAVAEMKRLMVE
HHHHCCEEEECCCCCCCCCCCCHHHCCHHHEECCCHHHHHHHHHHCCCHHHHHHHHHHHC
GRNG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA