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The map label for this gene is csd [H]

Identifier: 119944416

GI number: 119944416

Start: 828844

End: 830106

Strand: Direct

Name: csd [H]

Synonym: Ping_0644

Alternate gene names: 119944416

Gene position: 828844-830106 (Clockwise)

Preceding gene: 119944415

Following gene: 119944417

Centisome position: 18.18

GC content: 40.3

Gene sequence:

>1263_bases
TTGTTTTTTGTTACGGAATTAAAAGGTGAAATAATTTTGTCAAACTCTTCTTTTTGCGTTTATCAAATACGTCAGCATTT
TCCGATTCTAGATCAAATGATTAATGAACATCCTTTGATCTATTTAGATAACGCGGCGACGACCCAAAAACCCCAAGCTA
TGGTGGATGCCATTGCTGCATATTATTTGCGTGATAACGCCAATGTACACCGCGGCAGCCATCATCTGAGCCTTCGCGCG
ACGGCCGCATTTGAGGGCGTTAGAGAGACCGTAAAAACATTTATTAATGCCAAAAACACAAAAGAAATCATCTGGACAAA
AGGCACAACGGAAGGCATTAATTTATTAGCCAATGTATTATCTAAAGGCTTGAAAGCCGGTGATGAAGTCATTATCAGTG
CATTGGAGCACCATGCAAATATTGTGCCCTGGCAAATGCTGGTAGAATCACTGGGTATCGTTTTAAAAATCATTCCATTG
ACCCTGCAGCAGGATTTAGATTTAAAGAGTTACCAGAAACTATTAAGTGCAAAAACCAAAATTGTATCGGTCACCCATAT
CTCCAATGCATTAGGCGTTATTAATCCTATTAAAGAGATAATAAAACTGGCTCATCAGGTTGGCGCTCAGGTTATTATTG
ATGGTGCCCAGGCAGTTGGGCATTTAATCGTTGATGTAAAGGATCTTGACTGTGATTATTACGTTTTTTCCGGCCATAAA
TTATTTTCCCCAACAGGAGTAGGTGTTTTATACGGCAAACAGCACCTTTTAGAAGCCCTACCTCCCTGGCAGGGTGGCGG
AGAGATGATTAAAACGGTGAGTTTTGAAAAAAGTACTTTTAACCAATTACCTTTTAAGTTTGAAGCGGGTACGCCTAATA
TTGCCGGTATAATAGGGATGGGTGCAGCCATTGATTTTATCCGTGTTTTTAACCGCCAGGATTTGATTGATCATGAACAG
TCATTATTAACTTTCACGGAAAAAGCGTTATTAGAGCTCCCTGCTATCACTGTTTTTTATGAAGGCGGAGTTAAGTCTGG
TGCGCTCAGTTTTGCGGTTAAAGGTGAACACCCAAGTGATATTGCGATGTTATTAGATGCGCAGGGTATTGCTGTGCGCA
GTGGAATGCATTGTGCTATGCCCCTAATGGCGGAACTTAATTGCAAAGGCACCGTAAGAGTCTCATTTTCAATTTATAAT
ACCCATGAGGAAGCTGAGCGTTTTATTGAAGCGCTGAAAAAAATATTGGAAATGTTAGAGTAA

Upstream 100 bases:

>100_bases
GTTTTCCCGGCGCCTAAATAGATCACTTAATTAGTGGAATTGGTATACAACAATTAGCTGAATATTATGCAGTACTTGTA
CTGAGGGTATCATCGCGGTA

Downstream 100 bases:

>100_bases
GTTTTTATCGGTTAGCCGACTTCAAGCCCTTTGCCGTACTGATTGATGCGGCTTATTTTTTATTCCTTGCCCCTTTTGTA
TGCTGTACCGCTTCTTCAAA

Product: cysteine desulfurases, SufS subfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MFFVTELKGEIILSNSSFCVYQIRQHFPILDQMINEHPLIYLDNAATTQKPQAMVDAIAAYYLRDNANVHRGSHHLSLRA
TAAFEGVRETVKTFINAKNTKEIIWTKGTTEGINLLANVLSKGLKAGDEVIISALEHHANIVPWQMLVESLGIVLKIIPL
TLQQDLDLKSYQKLLSAKTKIVSVTHISNALGVINPIKEIIKLAHQVGAQVIIDGAQAVGHLIVDVKDLDCDYYVFSGHK
LFSPTGVGVLYGKQHLLEALPPWQGGGEMIKTVSFEKSTFNQLPFKFEAGTPNIAGIIGMGAAIDFIRVFNRQDLIDHEQ
SLLTFTEKALLELPAITVFYEGGVKSGALSFAVKGEHPSDIAMLLDAQGIAVRSGMHCAMPLMAELNCKGTVRVSFSIYN
THEEAERFIEALKKILEMLE

Sequences:

>Translated_420_residues
MFFVTELKGEIILSNSSFCVYQIRQHFPILDQMINEHPLIYLDNAATTQKPQAMVDAIAAYYLRDNANVHRGSHHLSLRA
TAAFEGVRETVKTFINAKNTKEIIWTKGTTEGINLLANVLSKGLKAGDEVIISALEHHANIVPWQMLVESLGIVLKIIPL
TLQQDLDLKSYQKLLSAKTKIVSVTHISNALGVINPIKEIIKLAHQVGAQVIIDGAQAVGHLIVDVKDLDCDYYVFSGHK
LFSPTGVGVLYGKQHLLEALPPWQGGGEMIKTVSFEKSTFNQLPFKFEAGTPNIAGIIGMGAAIDFIRVFNRQDLIDHEQ
SLLTFTEKALLELPAITVFYEGGVKSGALSFAVKGEHPSDIAMLLDAQGIAVRSGMHCAMPLMAELNCKGTVRVSFSIYN
THEEAERFIEALKKILEMLE
>Mature_420_residues
MFFVTELKGEIILSNSSFCVYQIRQHFPILDQMINEHPLIYLDNAATTQKPQAMVDAIAAYYLRDNANVHRGSHHLSLRA
TAAFEGVRETVKTFINAKNTKEIIWTKGTTEGINLLANVLSKGLKAGDEVIISALEHHANIVPWQMLVESLGIVLKIIPL
TLQQDLDLKSYQKLLSAKTKIVSVTHISNALGVINPIKEIIKLAHQVGAQVIIDGAQAVGHLIVDVKDLDCDYYVFSGHK
LFSPTGVGVLYGKQHLLEALPPWQGGGEMIKTVSFEKSTFNQLPFKFEAGTPNIAGIIGMGAAIDFIRVFNRQDLIDHEQ
SLLTFTEKALLELPAITVFYEGGVKSGALSFAVKGEHPSDIAMLLDAQGIAVRSGMHCAMPLMAELNCKGTVRVSFSIYN
THEEAERFIEALKKILEMLE

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=404, Percent_Identity=26.2376237623762, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI156713448, Length=303, Percent_Identity=27.3927392739274, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1787970, Length=404, Percent_Identity=47.7722772277228, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1789175, Length=403, Percent_Identity=41.6873449131514, Blast_Score=334, Evalue=7e-93,
Organism=Escherichia coli, GI48994898, Length=397, Percent_Identity=25.6926952141058, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25143064, Length=217, Percent_Identity=31.3364055299539, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI193211090, Length=379, Percent_Identity=23.7467018469657, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=228, Percent_Identity=30.2631578947368, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI20129463, Length=433, Percent_Identity=26.7898383371824, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022471
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 46287; Mature: 46287

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFVTELKGEIILSNSSFCVYQIRQHFPILDQMINEHPLIYLDNAATTQKPQAMVDAIAA
CEEEEEECCEEEEECCCEEEEEHHHCCCHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHH
YYLRDNANVHRGSHHLSLRATAAFEGVRETVKTFINAKNTKEIIWTKGTTEGINLLANVL
HHHHCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHH
SKGLKAGDEVIISALEHHANIVPWQMLVESLGIVLKIIPLTLQQDLDLKSYQKLLSAKTK
HHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IVSVTHISNALGVINPIKEIIKLAHQVGAQVIIDGAQAVGHLIVDVKDLDCDYYVFSGHK
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCEEEEEEEECCCCEEEEECCE
LFSPTGVGVLYGKQHLLEALPPWQGGGEMIKTVSFEKSTFNQLPFKFEAGTPNIAGIIGM
EECCCCCEEECCHHHHHHHCCCCCCCCHHEEEEEECHHHHHCCCEEEECCCCCCHHHHHH
GAAIDFIRVFNRQDLIDHEQSLLTFTEKALLELPAITVFYEGGVKSGALSFAVKGEHPSD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCCCCCC
IAMLLDAQGIAVRSGMHCAMPLMAELNCKGTVRVSFSIYNTHEEAERFIEALKKILEMLE
EEEEEECCCEEEECCCCHHCCHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFFVTELKGEIILSNSSFCVYQIRQHFPILDQMINEHPLIYLDNAATTQKPQAMVDAIAA
CEEEEEECCEEEEECCCEEEEEHHHCCCHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHH
YYLRDNANVHRGSHHLSLRATAAFEGVRETVKTFINAKNTKEIIWTKGTTEGINLLANVL
HHHHCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHH
SKGLKAGDEVIISALEHHANIVPWQMLVESLGIVLKIIPLTLQQDLDLKSYQKLLSAKTK
HHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IVSVTHISNALGVINPIKEIIKLAHQVGAQVIIDGAQAVGHLIVDVKDLDCDYYVFSGHK
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCEEEEEEEECCCCEEEEECCE
LFSPTGVGVLYGKQHLLEALPPWQGGGEMIKTVSFEKSTFNQLPFKFEAGTPNIAGIIGM
EECCCCCEEECCHHHHHHHCCCCCCCCHHEEEEEECHHHHHCCCEEEECCCCCCHHHHHH
GAAIDFIRVFNRQDLIDHEQSLLTFTEKALLELPAITVFYEGGVKSGALSFAVKGEHPSD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCCCCCC
IAMLLDAQGIAVRSGMHCAMPLMAELNCKGTVRVSFSIYNTHEEAERFIEALKKILEMLE
EEEEEECCCEEEECCCCHHCCHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]