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The map label for this gene is siaT [H]

Identifier: 119944311

GI number: 119944311

Start: 688039

End: 689412

Strand: Reverse

Name: siaT [H]

Synonym: Ping_0538

Alternate gene names: 119944311

Gene position: 689412-688039 (Counterclockwise)

Preceding gene: 119944312

Following gene: 119944310

Centisome position: 15.12

GC content: 46.07

Gene sequence:

>1374_bases
ATGGCGATGTTAACCCTTTTTCTAATGGTGATTGTATTCATGACGGTCGGTGTGCCTATTGCGGTTTCACTGGGTCTGTC
GAGTATGATCTTTTTATTAATACATTCTGATGCGTCGCTCGCGTCAGTCGCACAAACACTGTTTAACGCGTTTGCCGGAC
ATTATACTTTATTGGCCATCCCTTTCTTTGTATTAGCCTCCAGTTTTATGGCAACGGGTGGCGTCGCTAAGCGGATTATA
CGTTTTGCGATCGCAATAGTGGGCTCACTGCGTGGTGGTCTGGCAATGGCCTCGGTGGTTGCCTGTATGATGTTTGCTGC
CCTGTCGGGATCGTCTCCGGCAACCGTTGTTGCAATTGGTGGGATCGTTATTGCCGGAATGGTCAAAAATGGTTACAGCA
AAGATTTTGCAGCAGGTGTTATCTGTAATGCCGGCACCTTAGGGATTTTGATTCCGCCCTCGATCGTGATGGTGGTTTAT
GCGGCGGCGACGGATGTGTCTGTCGGGCGAATGTTCTTAGGTGGCGTTATACCCGGTTTGCTCGCGGGTTTAATGCTGAT
GATTGCTATCTATATTTATGCGCGGATTAAGAATATTCCGGCTCAGCCTTTTGTTGGCTGGAAAGAGGTTTTTGATTCGG
CTAAAGAGGCGGGTTGGGGATTACTGCTGATTGTTATTATTCTTGGCGGGATTTATGGCGGTATCTTTACACCGACCGAG
GCCGCGGCTGTAGCGGCAGTTTATGCCTTTTTTATCTCTAATTTTATCTATAAAGATATGGGGCCTTTATCCGATAAAGA
GCCTGAGGAGAAACGGGCTAAAGCATACTGGCGTAAAGCGTCACATGTATTTTTTCATGAAGATACCCGTAAAACCCTCT
ATGAAGCGGGCAAATTAACGATTATGTTAATGTTTATTGTTGCCAATGCTCTGATTTTAAAGCATGTTCTAACTGAAGAG
CAGATCCCGCAAATGATCACCGCATCAATGCTCGATGCCGGTCTAGGCCCTATCACTTTCCTTATTGTGGTTAATATCAT
CTTATTAATCGGTGGCCAATTTATGGAGCCCTCCGGCCTGCTTATTATCGTTGCGCCTTTGGTCTTTCCAATTGCAACAT
CATTGGGCATTGATCCTATTCACCTTGGTATTATGATGGTGGTGAATATGGAGATAGGCATGATAACCCCACCCGTAGGA
CTGAATCTGTTTGTGACCGCTGGTGTTGCACAGATGTCGGTGATGAAGGTAGTGAAAGCCTCGTTGCCGCTAGTGTGTGT
TATGTTCGTCTTCTTGATGATAGTCACTTATGTACCCTGGGTTTCAACCTGGTTACCCACCCTGATGATGGGACCTGAGA
TTATTACTCACTAA

Upstream 100 bases:

>100_bases
CCTGGCTGGTTGCCACCAACAAAATAGATAAGATGATTGCAAGTCATGAAGCCGAAGAAGATTTAGATTCGTTACACAAT
TCAGAGAAAGGAGAATAATT

Downstream 100 bases:

>100_bases
CAGCAAATCTATTAAATATGTGGTCATGCATTGGACACGAAAAATTAATCTGCAATGCTGATCACATCATTAATTTTTTG
GTATAACTTCAAGACGTAAA

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MAMLTLFLMVIVFMTVGVPIAVSLGLSSMIFLLIHSDASLASVAQTLFNAFAGHYTLLAIPFFVLASSFMATGGVAKRII
RFAIAIVGSLRGGLAMASVVACMMFAALSGSSPATVVAIGGIVIAGMVKNGYSKDFAAGVICNAGTLGILIPPSIVMVVY
AAATDVSVGRMFLGGVIPGLLAGLMLMIAIYIYARIKNIPAQPFVGWKEVFDSAKEAGWGLLLIVIILGGIYGGIFTPTE
AAAVAAVYAFFISNFIYKDMGPLSDKEPEEKRAKAYWRKASHVFFHEDTRKTLYEAGKLTIMLMFIVANALILKHVLTEE
QIPQMITASMLDAGLGPITFLIVVNIILLIGGQFMEPSGLLIIVAPLVFPIATSLGIDPIHLGIMMVVNMEIGMITPPVG
LNLFVTAGVAQMSVMKVVKASLPLVCVMFVFLMIVTYVPWVSTWLPTLMMGPEIITH

Sequences:

>Translated_457_residues
MAMLTLFLMVIVFMTVGVPIAVSLGLSSMIFLLIHSDASLASVAQTLFNAFAGHYTLLAIPFFVLASSFMATGGVAKRII
RFAIAIVGSLRGGLAMASVVACMMFAALSGSSPATVVAIGGIVIAGMVKNGYSKDFAAGVICNAGTLGILIPPSIVMVVY
AAATDVSVGRMFLGGVIPGLLAGLMLMIAIYIYARIKNIPAQPFVGWKEVFDSAKEAGWGLLLIVIILGGIYGGIFTPTE
AAAVAAVYAFFISNFIYKDMGPLSDKEPEEKRAKAYWRKASHVFFHEDTRKTLYEAGKLTIMLMFIVANALILKHVLTEE
QIPQMITASMLDAGLGPITFLIVVNIILLIGGQFMEPSGLLIIVAPLVFPIATSLGIDPIHLGIMMVVNMEIGMITPPVG
LNLFVTAGVAQMSVMKVVKASLPLVCVMFVFLMIVTYVPWVSTWLPTLMMGPEIITH
>Mature_456_residues
AMLTLFLMVIVFMTVGVPIAVSLGLSSMIFLLIHSDASLASVAQTLFNAFAGHYTLLAIPFFVLASSFMATGGVAKRIIR
FAIAIVGSLRGGLAMASVVACMMFAALSGSSPATVVAIGGIVIAGMVKNGYSKDFAAGVICNAGTLGILIPPSIVMVVYA
AATDVSVGRMFLGGVIPGLLAGLMLMIAIYIYARIKNIPAQPFVGWKEVFDSAKEAGWGLLLIVIILGGIYGGIFTPTEA
AAVAAVYAFFISNFIYKDMGPLSDKEPEEKRAKAYWRKASHVFFHEDTRKTLYEAGKLTIMLMFIVANALILKHVLTEEQ
IPQMITASMLDAGLGPITFLIVVNIILLIGGQFMEPSGLLIIVAPLVFPIATSLGIDPIHLGIMMVVNMEIGMITPPVGL
NLFVTAGVAQMSVMKVVKASLPLVCVMFVFLMIVTYVPWVSTWLPTLMMGPEIITH

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=426, Percent_Identity=34.7417840375587, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 48667; Mature: 48536

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
>Mature Secondary Structure 
AMLTLFLMVIVFMTVGVPIAVSLGLSSMIFLLIHSDASLASVAQTLFNAFAGHYTLLAI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
PFFVLASSFMATGGVAKRIIRFAIAIVGSLRGGLAMASVVACMMFAALSGSSPATVVAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHH
GIVIAGMVKNGYSKDFAAGVICNAGTLGILIPPSIVMVVYAAATDVSVGRMFLGGVIPGL
HHHHHHHHHCCCCCHHHHHEEECCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LAGLMLMIAIYIYARIKNIPAQPFVGWKEVFDSAKEAGWGLLLIVIILGGIYGGIFTPTE
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHH
AAAVAAVYAFFISNFIYKDMGPLSDKEPEEKRAKAYWRKASHVFFHEDTRKTLYEAGKLT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEEECHHHHHHHHCCHHH
IMLMFIVANALILKHVLTEEQIPQMITASMLDAGLGPITFLIVVNIILLIGGQFMEPSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
LIIVAPLVFPIATSLGIDPIHLGIMMVVNMEIGMITPPVGLNLFVTAGVAQMSVMKVVKA
EEEHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
SLPLVCVMFVFLMIVTYVPWVSTWLPTLMMGPEIITH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]